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4-Fluoroacetophenone

4-Fluoroacetophenone Structure
4-Fluoroacetophenone structure
CAS No.
403-42-9
Chemical Name:
4-Fluoroacetophenone
Synonyms
1-(4-Fluorophenyl)ethan-1-one;1-(4-FLUOROPHENYL)ETHANONE;4-Fluoracetophenon;P-FLUOROACETOPHENONE;p-Fluoro;AKOS BBS-00003234;4-FLUOROCETOPHENONE;Fluoroacetophenone3;4-FLUOROACETOPHENONE;4-Acetylfluorobenzene
CBNumber:
CB6419110
Molecular Formula:
C8H7FO
Molecular Weight:
138.14
MDL Number:
MFCD00000354
MOL File:
403-42-9.mol
MSDS File:
SDS
Last updated:2026-01-13 11:23:39
Product description Number Pack Size Price
4′-Fluoroacetophenone 99% F3207 25g $56.1
4′-Fluoroacetophenone 99% F3207 100g $97.5
4'-Fluoroacetophenone >98.0%(GC) F0261 25g $41
4'-Fluoroacetophenone >98.0%(GC) F0261 500g $486
4''-Fluoroacetophenone F401793 5g $60
More product size
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4-Fluoroacetophenone Properties

Melting point 4 °C
Boiling point 77-78 °C10 mm Hg(lit.)
Density 1.143 g/mL at 20 °C(lit.)
refractive index n20/D 1.511(lit.)
Flash point 160 °F
storage temp. Sealed in dry,Room Temperature
solubility Chloroform, Ethyl Acetate
form Liquid
Specific Gravity 1.138
color Clear colorless to slightly yellow
BRN 386013
InChI 1S/C8H7FO/c1-6(10)7-2-4-8(9)5-3-7/h2-5H,1H3
InChIKey ZDPAWHACYDRYIW-UHFFFAOYSA-N
SMILES CC(=O)c1ccc(F)cc1
CAS DataBase Reference 403-42-9(CAS DataBase Reference)
FDA UNII TVQ090602V
NIST Chemistry Reference Ethanone, 1-(4-fluorophenyl)-(403-42-9)
EPA Substance Registry System 4'-Fluoroacetophenone (403-42-9)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H227-H315-H319-H335
Precautionary statements  P210e-P261-P280a-P305+P351+P338-P405-P501a
PPE Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-23
WGK Germany  3
TSCA  TSCA listed
HazardClass  IRRITANT
HS Code  29147090
Storage Class 10 - Combustible liquids
NFPA 704
2
2 0

4-Fluoroacetophenone price More Price(46)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich F3207 4′-Fluoroacetophenone 99% 403-42-9 25g $56.1 2025-07-31 Buy
Sigma-Aldrich F3207 4′-Fluoroacetophenone 99% 403-42-9 100g $97.5 2025-07-31 Buy
TCI Chemical F0261 4'-Fluoroacetophenone >98.0%(GC) 403-42-9 25g $41 2025-07-31 Buy
TCI Chemical F0261 4'-Fluoroacetophenone >98.0%(GC) 403-42-9 500g $486 2025-07-31 Buy
TRC F401793 4''-Fluoroacetophenone 403-42-9 5g $60 2021-12-16 Buy
Product number Packaging Price Buy
F3207 25g $56.1 Buy
F3207 100g $97.5 Buy
F0261 25g $41 Buy
F0261 500g $486 Buy
F401793 5g $60 Buy

4-Fluoroacetophenone Chemical Properties,Uses,Production

Chemical Properties

Clear colorless to slightly yellow liquid

Uses

4’Fluoroacetophenone is an intermediate used for the synthetic preparation of various pharmaceutical good and agricultural products.

Uses

4-Fluoroacetophenone can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes.

Uses

4’-Fluoroacetophenone is an intermediate used for the synthetic preparation of various pharmaceutical good and agricultural products.

Reactions

4-Fluoroacetophenone is a versatile aromatic ketone, it can undergo nucleophilic substitution and acylation reactions.

Hazard

4-Fluoroacetophenone is a combustible liquid, it causes skin irritation and serious eye irritation.

Synthesis

Synthesis_403-42-9
General procedure: Oximes (1.0 mmol), Amberlyst-15 (0.02 g), FPA53-NO2(0.02 g), and solvent (1.5 mL) were introduced into a 25-cm-high, 90-mL autoclave with a glass tube inside equipped with magnetic stirrer (Scheme 2). Then the autoclave was charged with oxygen to 0.1 MPa. The reaction mixture was stirred at desirable temperature for special time. Progress of the reaction was monitored by thin-layer chromatography (TLC) or gas chromatography (GC). After the reaction, the resin (Amberlyst-15 and FPA53-NO2) was separated from the reaction mixture by filtration and extracted with 3 mL CH3CN (2 1.5 ml). The solvent was removed under reduced pressure. The residue was further purified by column chromatography on silica gel (300 mesh) with hexane/ethyl acetate to give the 4-Fluoroacetophenone.

4-Fluoroacetophenone synthesis

766-98-3
403-42-9
Synthesis of 4-Fluoroacetophenone from 4-Fluorophenylacetylene

4-Fluoroacetophenone Preparation Products And Raw materials

Raw materials

Preparation Products

2-(4-FLUOROPHENYL)-1H-INDOLE-3-CARBALDEHYDE 4'-PIPERAZINOACETOPHENONE 2-(4-FLUOROBENZOYL)-1-BENZOFURAN-5-CARBALDEHYDE ETHYL 2-AMINO-4-(4-FLUOROPHENYL)THIOPHENE-3-CARBOXYLATE 4-(4-Fluorophenyl)pyrimidine-2-thiol
4-Fluorophenylacetylene 4'-Phenoxyacetophenone 1-(4-FLUOROPHENYL)ETHYLAMINE 5-(4-FLUOROPHENYL)-3H-THIENO[2,3-D]PYRIMIDIN-4-ONE 2-Bromo-4'-fluoroacetophenone
ALPHA,ALPHA-DIBROMO-4-FLUOROACETOPHENONE 6-(4-FLUOROPHENYL)INDOLE 4-FLUOROBENZOYLACETONITRILE 3-(4-FLUOROPHENYL)-1H-PYRAZOLE-4-CARBALDEHYDE 5-(4-Fluorophenyl)thiophene-2-carboxylic acid
1-(4-Fluorophenyl)-3-(2-thienyl)-2-propen-1-one/alpha-(2-Thienylidene)-4-fluoroacetophenone 2-(4-FLUOROPHENYL)QUINOLINE

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4-Fluoroacetophenone Suppliers

Global( 657)Suppliers
Supplier Tel Email Country ProdList Advantage
Nanjing Sinoda Biological Technology Co., Ltd
+8613401983379 sales@njmcn.cn CHINA 74 58
Changzhou Ditong Chemical Co.,Ltd
+86-0519-88298848 info@edengenechem.com China 2176 58
Handan Tongyi New Material Technology Co., Ltd
+8617330042575 ty003@handantongyi.com China 351 58
SINO HIGH(CHINA)CO.,LTD.
+86-2558392388 +86-13914336446 chang@sinohighchem.com China 34 58
Shandong Vital Biotechnology Co., Ltd.
+8617860230571 biotechcaroline@gmail.com China 87 58
Ningbo Banco Chemical Technology Co., Ltd.
+86-15827200700 sales@bancochemical.com China 487 58
RongNa Biotechnology Co.,Ltd 		+86-86-13583358881 +8618560316533 Brad@rongnabiotech.com China 3387 58
Hebei Chuanghai Biotechnology Co,.LTD 		+86-13131129325 sales1@chuanghaibio.com China 5242 58
Hebei Chuanghai Biotechnology Co., Ltd 		+8615531151365 mina@chuanghaibio.com China 18126 58
Firsky International Trade (Wuhan) Co., Ltd 		+8615387054039 admin@firsky-cn.com China 427 58
Supplier Advantage
Nanjing Sinoda Biological Technology Co., Ltd
58
Changzhou Ditong Chemical Co.,Ltd
58
Handan Tongyi New Material Technology Co., Ltd
58
SINO HIGH(CHINA)CO.,LTD.
58
Shandong Vital Biotechnology Co., Ltd.
58
Ningbo Banco Chemical Technology Co., Ltd.
58
RongNa Biotechnology Co.,Ltd 		58
Hebei Chuanghai Biotechnology Co,.LTD 		58
Hebei Chuanghai Biotechnology Co., Ltd 		58
Firsky International Trade (Wuhan) Co., Ltd 		58

Related articles

View Lastest Price from 4-Fluoroacetophenone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Fluoroacetophenone pictures 2026-02-10 4-Fluoroacetophenone
403-42-9
 US $10.00 / ASSAYS 1ASSAYS 99% 1 ton RongNa Biotechnology Co.,Ltd
4-Fluoroacetophenone pictures 2026-02-10 4-Fluoroacetophenone
403-42-9
 US $3.00 / kg 1kg 99.5% 500mt Jinan Finer Chemical Co., Ltd
4-Fluoroacetophenone pictures 2025-12-01 4-Fluoroacetophenone
403-42-9
 US $0.00 / kg 1kg 99% 10000KGS Shaanxi Dideu New Materials Co. Ltd

4-Fluoroacetophenone Spectrum

4-Fluoroacetophenone(403-42-9)MS4-Fluoroacetophenone(403-42-9)1HNMR4-Fluoroacetophenone(403-42-9)13CNMR4-Fluoroacetophenone(403-42-9)IR14-Fluoroacetophenone(403-42-9)Raman

403-42-9(4-Fluoroacetophenone)Related Search:

4'-Methylacetophenone 4-Nitroacetophenone 4'-(Trifluoromethyl)acetophenone L-PICEIN 2-Bromoacetophenone
Acetophenone 3-Nitroacetophenone 4'-Hydroxyacetophenone 4'-Fluoropropiophenone 1-(4-FLUORO-PHENYL)-BUTAN-1-ONE
4-Dechloro-4-(4-chlorophenyl) Haloperidol Decanoate Haloperidol Lauroate 4-Defluoro-2-fluoro Haloperidol Decanoate 4-[4-(4-Chlorophenyl)-4-hydroxypiperidine]-4-defluorohaloperidol Decanoate Haloperidol Octanoate
4-Dechloro-4-(3-chlorophenyl) Haloperidol Decanoate ODANWSUZWFYXTO-UHFFFAOYSA-N 4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]-4-piperidyl decanoate

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Acetophenone, 4'-fluoro- para-Fluoroacetophenone P-FLUOROACETOPHENONE 4-FLUOROCETOPHENONE 4-FLUOROACETOPHENONE AKOS BBS-00003234 1-(4-Fluorophenyl)ethan-1-one Fluoroacetophenone color less liq Fluoroacetophenone3 4'-Fluoroacetophenone 1-(4-Fluorophenyl)ethan-1-one 1-(4-Fluorophenyl)ethanone 4-Fluoroacetophenone,99% LABOTEST-BB LT01148215 1-(4-FLUOROPHENYL)ETHANONE p-Fluoro 4'-Fluoroacetophenone 99% Ethanone, 1-(4-fluorophenyl)- p-Fluorophenyl methyl ketone 1-(4-fluorophenyl)-ethanon 1-Acetyl-4-fluorobenzene 4-Acetylphenyl fluoride Methyl 4-fluorophenyl ketone 4-Acetylfluorobenzene 4-Fluorophenyl Methyl ketone 4-Fluorophenylethanal Methyl 4-fluorophenyl Of Fluoroacetophenone 1-(4-Fluorophenyl)ethan-1-one, 1-(4-Fluorophenyl)-1-oxoethane The fluorine acetophenone 4'-Fluoroacetophenone> 4'-Fluoroacetophenone, 99%, for synthesis Haloperidol Decanoate EP Impurity L Haloperidol Decanoate Impurity 12（Haloperidol Decanoate EP Impurity L） Lidocaine Pharmaceutical Drugs 4-Fluoracetophenon Bromperidol decanoate EP Impurity L TIANFU-CHEM 4-Fluoroacetophenone 4-Fluoroacetophenone pure, 98% Haloperidol EP Impurity L 4-FLOURO ACETOPHENONE 4'-Fluoroacetophenone Haloperidol Decanoate Impurity L 4'-Fluoroacetophenone, 95% 4′-Fluoroacetophenone, CAS 403-42-9 403-42-9 2200-10-2 C7 to C8 Carbonyl Compounds Building Blocks Organic Building Blocks Ketones Adehydes, Acetals & Ketones Fluorine Compounds C7 to C8 Carbonyl Compounds Ketones Acetophenone series Benzenes Aromatic Acetophenones & Derivatives (substituted)