3-Methyl-2-nitroaniline
- CAS No.
- 601-87-6
- Chemical Name:
- 3-Methyl-2-nitroaniline
- Synonyms
- 3-Methyl-2-nitrobenzenamine;2-NITRO-M-TOLUIDINE;3-AMINO-2-NITROTOLUENE;3-METHYL-2-NITROANILINE;2-NITRO-3-METHYL ANILINE;3-Methyl-2-nitroaniline 97%;3-Methyl-2-nitro-phenylamine;Benzenamine,3-methyl-2-nitro-;3-Amino-2-nitrotoluene 10 μg/mL in Acetonitrile;3-Amino-2-nitrotoluene, 2-Amino-6-methylnitrobenzene
- CBNumber:
- CB6432197
- Molecular Formula:
- C7H8N2O2
- Molecular Weight:
- 152.15
- MDL Number:
- MFCD00074851
- MOL File:
- 601-87-6.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 3-Amino-2-nitrotoluene | FA152737 | 1g | $150 |
| 3-Methyl-2-nitroaniline 98% | AS33855 | 1g | $22 |
| 3-Methyl-2-nitroaniline 98% | AS33855 | 5g | $33 |
| 3-Methyl-2-nitroaniline 97% | OR16981 | 1g | $25 |
| 3-Methyl-2-nitroaniline 98% | AS33855 | 25g | $92 |
| More product size | |||
| Melting point | 107-108 °C |
|---|---|
| Boiling point | 288.6±20.0 °C(Predicted) |
| Density | 1.269±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | crystalline powder |
| pka | -0.11±0.10(Predicted) |
| color | Orange |
| InChI | InChI=1S/C7H8N2O2/c1-5-3-2-4-6(8)7(5)9(10)11/h2-4H,8H2,1H3 |
| InChIKey | VDCZKCIEXGXCDJ-UHFFFAOYSA-N |
| SMILES | C1(N)=CC=CC(C)=C1[N+]([O-])=O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| HS Code | 2921420090 |
3-Methyl-2-nitroaniline price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FA152737 | 3-Amino-2-nitrotoluene | 601-87-6 | 1g | $150 | 2026-06-04 | Buy |
| Activate Scientific | AS33855 | 3-Methyl-2-nitroaniline 98% | 601-87-6 | 1g | $22 | 2026-06-04 | Buy |
| Activate Scientific | AS33855 | 3-Methyl-2-nitroaniline 98% | 601-87-6 | 5g | $33 | 2026-06-04 | Buy |
| Apolloscientific | OR16981 | 3-Methyl-2-nitroaniline 97% | 601-87-6 | 1g | $25 | 2026-06-04 | Buy |
| Activate Scientific | AS33855 | 3-Methyl-2-nitroaniline 98% | 601-87-6 | 25g | $92 | 2026-06-04 | Buy |
3-Methyl-2-nitroaniline Chemical Properties,Uses,Production
Uses
3-Methyl-2-nitroaniline is used in the purification of 2-Methoxy-5-trifluoromethoxybenzaldehyde. It also an important component in preparing benzimidazoles. It is used in palladium-catalyzed synthesis of quinoxline deriitives.
Synthesis
60310-07-8
601-87-6
General procedure for the synthesis of 3-methyl-2-nitroaniline from 3-methyl-2-nitrobenzamide: NaOH (2.220 g, 55.5 mmol) was dissolved in water (12 mL) at 0°C, followed by the addition of Br2 (0.322 mL, 6.26 mmol). Next, 3-methyl-2-nitrobenzamide (1 g, 5.55 mmol) was added all at once and the mixture was slowly heated in a water bath to 50-55°C (internal temperature), at which point oil droplets were observed to separate. The temperature was continued to be gradually increased to 70°C and maintained at this temperature for 1 hour. Subsequently, a solution of NaOH (0.7 g) dissolved in water (4 mL) was added and the temperature was slowly raised to 80°C and held for another 1 hour. After completion of the reaction, it was cooled to room temperature and extracted with EtOAc (3x50mL). The organic layers were combined, dried and concentrated to give 0.7 g (90% yield) of the target compound 3-methyl-2-nitroaniline.LC-MS analysis showed m/z of 153.1 (M + H)+ and retention time of 1.65 min.
References
[1] Patent: WO2015/92713, 2015, A1. Location in patent: Page/Page column 73; 74
[2] Patent: WO2016/203400, 2016, A1. Location in patent: Page/Page column 49
[3] Patent: WO2016/203401, 2016, A1. Location in patent: Page/Page column 60; 61
[4] Patent: WO2016/202253, 2016, A1. Location in patent: Page/Page column 126; 127
[5] Patent: WO2018/104766, 2018, A1. Location in patent: Page/Page column 60-61
3-Methyl-2-nitroaniline Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49979 | 58 | |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29793 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569262 +86-15003564040 | 1056@dideu.com | China | 3971 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 | contact@fuxinpharm.com | China | 9976 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34563 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14303 | 58 |
View Lastest Price from 3-Methyl-2-nitroaniline manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2022-02-21 | 3-Methyl-2-nitroaniline
601-87-6
|
1KG | 97.1% | 100 tons | Honest Joy Holdings Limited | ||
 |
2019-12-27 | 3-Methyl-2-nitroaniline
601-87-6
|
$1.00 | 1KG | 99% | 200kg | Career Henan Chemical Co |
-
- 3-Methyl-2-nitroaniline
601-87-6
- $0.00
- 97.1%
- Honest Joy Holdings Limited
-
- 3-Methyl-2-nitroaniline
601-87-6
- $1.00
- 99%
- Career Henan Chemical Co
