2-(4-TRIFLUOROMETHYL-PHENYL)-ETHYLAMINE
- CAS No.
- 775-00-8
- Chemical Name:
- 2-(4-TRIFLUOROMETHYL-PHENYL)-ETHYLAMINE
- Synonyms
- RARECHEM AL BW 0217;4-Trifluoromethylphenethylamine; p-(Trifluoromethyl)phenethylamine;2-(4-TRIFLUOROMETHYL-PHENYL)-ETHYLAMINE;2-[4-(TRIFLUOROMETHYL)PHENYL]ETHANAMINE;Benzeneethanamine, 4-(trifluoromethyl)-;2-[4-(trifluoroMethyl)phenyl]ethan-1-aMine;2-[4-(trifluoromethyl)phenyl]ethanamine(SALTDATA: FREE)
- CBNumber:
- CB6435749
- Molecular Formula:
- C9H10F3N
- Molecular Weight:
- 189.18
- MDL Number:
- MFCD01529875
- MOL File:
- 775-00-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 2-(4-Trifluoromethylphenyl)ethylamine >98.0%(GC)(T) | T3278 | 1g | $66 |
| 2-(4-Trifluoromethylphenyl)ethylamine >98.0%(GC)(T) | T3278 | 5g | $222 |
| 2-(4-TRIFLUOROMETHYL-PHENYL)-ETHYLAMINE 97% | 66806 | 1G | $37 |
| 2-(4-TRIFLUOROMETHYL-PHENYL)-ETHYLAMINE 97% | 66806 | 5G | $72 |
| 2-(4-Trifluoromethyl-phenyl)ethylamine ≥99%(GC) | 19917 | 250MG | $42.46 |
| More product size | |||
| Boiling point | 210℃ |
|---|---|
| Density | 1.186 |
| refractive index | 1.4620 to 1.4660 |
| Flash point | 86℃ |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| pka | 9.49±0.10(Predicted) |
| form | clear liquid |
| color | Colorless to Light yellow to Light orange |
| Water Solubility | Slightly soluble in water. |
| InChI | InChI=1S/C9H10F3N/c10-9(11,12)8-3-1-7(2-4-8)5-6-13/h1-4H,5-6,13H2 |
| InChIKey | HMFOBPNVAAAACP-UHFFFAOYSA-N |
| SMILES | C1(CCN)=CC=C(C(F)(F)F)C=C1 |
| CAS DataBase Reference | 775-00-8(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H314-H318 | |||||||||
| Precautionary statements | P260h-P301+P330+P331-P303+P361+P353-P305+P351+P338-P405-P501a | |||||||||
| RIDADR | UN 2735 8/PG II | |||||||||
| HazardClass | IRRITANT | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 2921490090 | |||||||||
| Limited Quantities | 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) | |||||||||
| NFPA 704 |
|
2-(4-TRIFLUOROMETHYL-PHENYL)-ETHYLAMINE price More Price(47)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | T3278 | 2-(4-Trifluoromethylphenyl)ethylamine >98.0%(GC)(T) | 775-00-8 | 1g | $66 | 2026-04-30 | Buy |
| TCI Chemical | T3278 | 2-(4-Trifluoromethylphenyl)ethylamine >98.0%(GC)(T) | 775-00-8 | 5g | $222 | 2026-04-30 | Buy |
| AstaTech | 66806 | 2-(4-TRIFLUOROMETHYL-PHENYL)-ETHYLAMINE 97% | 775-00-8 | 1G | $37 | 2026-04-30 | Buy |
| AstaTech | 66806 | 2-(4-TRIFLUOROMETHYL-PHENYL)-ETHYLAMINE 97% | 775-00-8 | 5G | $72 | 2026-04-30 | Buy |
| Chem-Impex | 19917 | 2-(4-Trifluoromethyl-phenyl)ethylamine ≥99%(GC) | 775-00-8 | 250MG | $42.46 | 2026-05-19 | Buy |
2-(4-TRIFLUOROMETHYL-PHENYL)-ETHYLAMINE Chemical Properties,Uses,Production
Chemical Properties
2-(4-Trifluoromethylphenyl)ethylamine is colorless transparent to light yellow liquid at room temperature and pressure, slightly soluble in water, easily soluble in toluene and other organic solvents.
Uses
It is applied as an active pharmaceutical intermediate.
Synthesis
2338-75-2
775-00-8
The general procedure for the synthesis of 2-(4-trifluoromethylphenyl)ethylamine from p-trifluoromethylphenylacetonitrile was as follows: (4-trifluoromethylphenyl)acetonitrile (2 g, 10.81 mmol) was dissolved in methanol-ammonia solution (50 mL), which was subsequently added to a Parr hydrogenation reactor that had been charged with nickel Nguyenay (400 mg). The reaction mixture was stirred overnight under hydrogen pressure of 50 psi. The progress of the reaction was monitored by thin layer chromatography (TLC, the unfolding agent was a chloroform solution containing 10% methanol). Upon completion of the reaction, the mixture was filtered through a bed of diatomaceous earth and the filtrate was concentrated and dried under reduced pressure to afford the target product 2-(4-trifluoromethylphenyl)ethylamine (2 g, 97.89% yield). The product was analyzed by LCMS and the purity was 98.73%, m/z = 190.0 ([M+H]+).
References
[1] Patent: WO2012/35078, 2012, A1. Location in patent: Page/Page column 67
[2] Patent: US2014/45872, 2014, A1. Location in patent: Paragraph 0403
[3] Patent: WO2004/82682, 2004, A1. Location in patent: Page 44-45
[4] Patent: WO2003/93231, 2003, A2. Location in patent: Page/Page column 48
[5] Patent: WO2005/80371, 2005, A1. Location in patent: Page/Page column 49
2-(4-TRIFLUOROMETHYL-PHENYL)-ETHYLAMINE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Fluoropharm Co., Ltd. | +86-0571-85586753 +86-13336034509 | sales@fluoropharm.com | China | 1445 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10403 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10000 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
View Lastest Price from 2-(4-TRIFLUOROMETHYL-PHENYL)-ETHYLAMINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-10 | 2-(4-TRIFLUOROMETHYL-PHENYL)-ETHYLAMINE
775-00-8
|
$1.00 | 1g | 99% | 10000KGS | Career Henan Chemical Co |
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- 2-(4-TRIFLUOROMETHYL-PHENYL)-ETHYLAMINE
775-00-8
- $1.00
- 99%
- Career Henan Chemical Co
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