1H-Benzimidazole-5-carboxylic acid
- CAS No.
- 15788-16-6
- Chemical Name:
- 1H-Benzimidazole-5-carboxylic acid
- Synonyms
- 1H-benzo[d]iMidazole-5-carboxylic acid;1H-Benzo[d]iMidazole-6-carboxylic acid;5-BENZIMIDAZOLECARBOXYLIC ACID;AURORA 9842;AKOS BBS-00000435;BenziMidazole-5-acid;OTAVA-BB BB7014211630;5-CARBOXYBENZIMIDAZOLE;4-caboxylic benzimidazole;5-caboxylic benziMidazole
- CBNumber:
- CB6435996
- Molecular Formula:
- C8H6N2O2
- Molecular Weight:
- 162.15
- MDL Number:
- MFCD00011555
- MOL File:
- 15788-16-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 5-Benzimidazolecarboxylic acid 96% | 296783 | 5g | $64.7 |
| 5-Benzimidazolecarboxylic acid 96% | 296783 | 25g | $283 |
| 5-Benzimidazolecarboxylic Acid >97.0%(T) | B1763 | 5g | $71 |
| 5-Benzimidazolecarboxylic Acid >97.0%(T) | B1763 | 25g | $282 |
| 1H-BENZIMIDAZOLE-5-CARBOXYLICACID 97% | CL3437 | 25G | $32 |
| More product size | |||
| Melting point | >300 °C (lit.) |
|---|---|
| Boiling point | 288.82°C (rough estimate) |
| Density | 1.3264 (rough estimate) |
| refractive index | 1.5770 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
| pka | 3.10±0.30(Predicted) |
| form | Powder |
| color | Green-gray to gray-brown |
| BRN | 5686 |
| InChI | InChI=1S/C8H6N2O2/c11-8(12)5-1-2-6-7(3-5)10-4-9-6/h1-4H,(H,9,10)(H,11,12) |
| InChIKey | COYPLDIXZODDDL-UHFFFAOYSA-N |
| SMILES | C1NC2=CC(C(O)=O)=CC=C2N=1 |
| CAS DataBase Reference | 15788-16-6(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29339900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
1H-Benzimidazole-5-carboxylic acid price More Price(39)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 296783 | 5-Benzimidazolecarboxylic acid 96% | 15788-16-6 | 5g | $64.7 | 2026-04-30 | Buy |
| Sigma-Aldrich | 296783 | 5-Benzimidazolecarboxylic acid 96% | 15788-16-6 | 25g | $283 | 2026-04-30 | Buy |
| TCI Chemical | B1763 | 5-Benzimidazolecarboxylic Acid >97.0%(T) | 15788-16-6 | 5g | $71 | 2026-04-30 | Buy |
| TCI Chemical | B1763 | 5-Benzimidazolecarboxylic Acid >97.0%(T) | 15788-16-6 | 25g | $282 | 2026-04-30 | Buy |
| AstaTech | CL3437 | 1H-BENZIMIDAZOLE-5-CARBOXYLICACID 97% | 15788-16-6 | 25G | $32 | 2026-04-30 | Buy |
1H-Benzimidazole-5-carboxylic acid Chemical Properties,Uses,Production
Chemical Properties
GREEN-GREY TO GREY-BROWN POWDER
Uses
A benzimidazole derivative that exhibits corrosion inhibiting properties against strong acids.
Uses
5-Benzimidazolecarboxylic acid has been used in the preparation of:
- 1H-benzoimidazole-5-carboxylic acid benzotriazol-1-yl ester
- piperidin-1-yl(1-m-tolyl-1H-benzo[d]imidazol-5-yl)methanone
General Description
Drug-specific monoclonal antibodies were produced against the very small drug hapten, 5-benzimidazolecarboxylic acid.
Synthesis
124-38-9
4887-88-1
15788-16-6
To a solution of 5-bromo-1H-benzimidazole (0.87 g, 4.4 mmol, 1.0 eq.) in anhydrous THF (20 mL) was slowly added 2 M isopropylmagnesium chloride (i-PrMgCl) in a solution of THF (2.2 mL, 4.4 mmol, 1.0 eq.) at 0 °C, keeping the reaction temperature not more than 20 °C. After addition, the clarified solution was continued to be stirred at 0 °C for 5 min. Subsequently, 2.5 M hexane solution (3.5 mL, 8.8 mmol, 2.0 eq.) of n-butyllithium (n-BuLi) was added dropwise over 5 min, controlling the temperature below 20 °C. The reaction mixture was stirred at the same temperature for 30 min. Then, dry carbon dioxide (0.20 g, 4.4 mmol, 1.0 eq.) was added to the reaction system and the mixture was slowly warmed to 20 °C over 30 min. Upon completion of the reaction, the reaction was quenched with deionized water (6 mL). After stirring at 20 °C for 10 min, the organic and aqueous phases were separated. The aqueous phase was extracted once with ethyl acetate (10 mL). The organic phases were combined, filtered through a 0.51 cm silica gel pad and eluted with ethyl acetate (10 mL). The filtrate was concentrated and the residue was purified by silica gel column chromatography (eluent: petroleum ether/ethyl acetate = 3:1) to afford 1H-benzimidazole-5-carboxylic acid (0.5 g, 71% yield) as a brown solid. The product was structurally confirmed by 1H-NMR (600 MHz, DMSO-d6) and 13C-NMR (151 MHz, DMSO-d6).
References
[1] Molecules, 2017, vol. 22, # 11,
1H-Benzimidazole-5-carboxylic acid Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29819 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Shanxi Xuanran Import and Export Trade Co., Ltd. | +8617735180244 | mike_yan@xuanranglobal.com | CHINA | 4017 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52705 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19987 | 58 |
| sgtlifesciences pvt ltd | +8617013299288 | dj@sgtlifesciences.com | China | 12373 | 58 |
| GLR Innovations | +91 9891111994 | info@glrgroup.in | India | 4535 | 58 |
View Lastest Price from 1H-Benzimidazole-5-carboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2022-02-09 | 1H-Benzimidazole-5-carboxylic acid
15788-16-6
|
US $0.00 / KG | 1KG | 98.3% | 100 tons | Honest Joy Holdings Limited | |
 |
2019-07-06 | 1H-Benzimidazole-5-carboxylic acid
15788-16-6
|
US $1.00 / KG | 1KG | 98% | 1kg,5kg,100kg | Career Henan Chemical Co |
-
- 1H-Benzimidazole-5-carboxylic acid
15788-16-6
- US $0.00 / KG
- 98.3%
- Honest Joy Holdings Limited
-
- 1H-Benzimidazole-5-carboxylic acid
15788-16-6
- US $1.00 / KG
- 98%
- Career Henan Chemical Co
