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(TERT-BUTYLDIMETHYLSILYLOXY)ACETALDEHYDE

(TERT-BUTYLDIMETHYLSILYLOXY)ACETALDEHYDE structure

CAS No.: 102191-92-4

Chemical Name:: (TERT-BUTYLDIMETHYLSILYLOXY)ACETALDEHYDE

Synonyms: 2-(tert-butyldimethylsilyloxy)acetaldehyde;DK447;oxy)acetaL;DKFELEX0096;T-BUTYLDIMETHYLSILOXYACETALDEHYDE;T-BUTYLDIMETHYLSILYLOXYACETALDEHYDE;t-BUTYLDIMETHYLSILOXYACETALDEHYDE,90%;DIMETHYL-TERT-BUTYLSILYLOXYACETALDEHYDE;(TERT-BUTYLDIMETHYLSILYLOXY)ACETALDEHYDE;2-(Tert-Butyldimethylsiloxy)acetaldehyde

CBNumber:: CB6436993

Molecular Formula:: C8H18O2Si

Molecular Weight:: 174.31

MDL Number:: MFCD01321229

MOL File:: 102191-92-4.mol

MSDS File:: SDS

Last updated:2026-01-13 11:24:59

Product description	Number	Pack Size	Price
(tert-Butyldimethylsilyloxy)acetaldehyde 90%	449458	1g	$95.9
(tert-Butyldimethylsilyloxy)acetaldehyde 90%	449458	5g	$375
2-[(tert-Butyldimethylsilyl)oxy]acetaldehyde min. 95.0 %	B6269	1G	$89
2-[(tert-Butyldimethylsilyl)oxy]acetaldehyde min. 95.0 %	B6269	5G	$270
(tert-Butyldimethylsilyloxy)acetaldehyde	B942745	500mg	$55
More product size

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(TERT-BUTYLDIMETHYLSILYLOXY)ACETALDEHYDE Properties

Melting point	165-167 ºC
Boiling point	165-167 °C(lit.)
Density	0.915 g/mL at 25 °C(lit.)
refractive index	n20/D 1.432(lit.)
Flash point	140 °F
storage temp.	2-8°C
form	Powder
color	White to light beige to grey
Specific Gravity	0.915
Hydrolytic Sensitivity	8: reacts rapidly with moisture, water, protic solvents
InChI	InChI=1S/C8H18O2Si/c1-8(2,3)11(4,5)10-7-6-9/h6H,7H2,1-5H3
InChIKey	MEBFFOKESLAUSJ-UHFFFAOYSA-N
SMILES	C(=O)CO[Si](C(C)(C)C)(C)C
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS02,GHS07
Signal word	Warning
Hazard statements	H226-H315-H319-H335
Precautionary statements	P210-P233-P240-P241-P303+P361+P353-P305+P351+P338
target organs	Respiratory system
PPE	Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
RIDADR	UN 1989 3/PG 3
WGK Germany	3
TSCA	No
HazardClass	3
HS Code	29319090
Storage Class	3 - Flammable liquids
Hazard Classifications	Eye Irrit. 2 Flam. Liq. 3 Skin Irrit. 2 STOT SE 3
Limited Quantities	5.0 L (1.3 gallons) (liquid)
Excepted Quantities	Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)

(TERT-BUTYLDIMETHYLSILYLOXY)ACETALDEHYDE price More Price(23)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	449458	(tert-Butyldimethylsilyloxy)acetaldehyde 90%	102191-92-4	1g	$95.9	2025-07-31	Buy
Sigma-Aldrich	449458	(tert-Butyldimethylsilyloxy)acetaldehyde 90%	102191-92-4	5g	$375	2025-07-31	Buy
TCI Chemical	B6269	2-[(tert-Butyldimethylsilyl)oxy]acetaldehyde min. 95.0 %	102191-92-4	1G	$89	2025-07-31	Buy
TCI Chemical	B6269	2-[(tert-Butyldimethylsilyl)oxy]acetaldehyde min. 95.0 %	102191-92-4	5G	$270	2025-07-31	Buy
TRC	B942745	(tert-Butyldimethylsilyloxy)acetaldehyde	102191-92-4	500mg	$55	2021-12-16	Buy

Product number	Packaging	Price	Buy
449458	1g	$95.9	Buy
449458	5g	$375	Buy
B6269	1G	$89	Buy
B6269	5G	$270	Buy
B942745	500mg	$55	Buy

(TERT-BUTYLDIMETHYLSILYLOXY)ACETALDEHYDE Chemical Properties,Uses,Production

Chemical Properties

Clear colorless to straw colored liquid

Uses

Employed in the construction of the key tetrahydropyran subunit in a recent synthesis of the marine natural product (–)-dactylodide.

Synthesis

102229-10-7

(TERT-BUTYLDIMETHYLSILYLOXY)ACETALDEHYDE

102191-92-4

Oxalyl chloride (13.7 mL, 162.2 mmol) was dissolved in anhydrous dichloromethane (400 mL) under nitrogen protection and cooled to -78°C. Dimethyl sulfoxide (25.1 mL, 353.9 mmol) was added slowly and stirred for 30 minutes. Subsequently, a solution of 2-((tert-butyldimethylsilyl)oxy)ethanol (26.0 g, 147.5 mmol) in anhydrous dichloromethane (100 mL) was added dropwise. After maintaining -78 °C and continuing to stir for 30 min, triethylamine (102.74 mL, 737.0 mmol) was added slowly and dropwise. The reaction mixture was stirred at -78 °C for another 30 min, then gradually warmed up to room temperature and continued stirring for 1 h. The reaction mixture was then stirred at -78 °C for 1 h. The reaction mixture was then gradually warmed up to room temperature. The pH of the reaction mixture was adjusted to 4 with aqueous 2N hydrochloric acid and then extracted with dichloromethane (3 x 400 mL). The organic layers were combined, dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give 2-((tert-butyldimethylsilyl)oxy)acetaldehyde (34.0 g, 100%) as a colorless oil. The product can be used directly in the subsequent reaction without further purification.

References

[1] Organic Letters, 2016, vol. 18, # 18, p. 4534 - 4537
[2] Patent: WO2017/24018, 2017, A1. Location in patent: Paragraph 00132
[3] Patent: US2016/122345, 2016, A1. Location in patent: Paragraph 0115; 0118
[4] Patent: US9481674, 2016, B1. Location in patent: Page/Page column 47; 48
[5] Patent: WO2017/87608, 2017, A1. Location in patent: Paragraph 00125; 00128

(TERT-BUTYLDIMETHYLSILYLOXY)ACETALDEHYDE Preparation Products And Raw materials

Raw materials

4,9-Dioxa-3,10-disiladodec-6-ene, 2,2,3,3,10,10,11,11-octamethyl-, (6Z)- (TERT.-BUTYLDIMETHYLSILYLOXY)ETHANOL 4,9-Dioxa-3,10-disiladodec-6-ene, 2,2,3,3,10,10,11,11-octamethyl- Triethylamine Dimethyl sulfoxide

Dichloromethane Oxalyl chloride

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Preparation Products

(S,E)-N-(2-(tert-butyldimethylsilyloxy)ethylidene)-2-methylpropane-2-sulfinamide (E)-4-[[(1,1-DiMethylethyl)diMethylsilyl]oxy]-2-butenoic Acid Ethyl Ester

(TERT-BUTYLDIMETHYLSILYLOXY)ACETALDEHYDE Suppliers

Global( 174)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	13636	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Zjartschem	+86-571 87238903	jocelynpan@zjarts.com	CHINA	988	58
Win-Win Chemical CO., Limited	0086-577-64498589	sales@win-winchemical.com	CHINA	998	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29795	58
Hubei Co-Formula Material Tech Co., Ltd.	+86-27-84459282	sales@cfmats.com	CHINA	882	58
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	sale04@alfachem.cn	China	11728	58

Supplier	Advantage
Shanghai Daken Advanced Materials Co.,Ltd	58
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
Zjartschem	58
Win-Win Chemical CO., Limited	58
Jinan Carbotang Biotech Co.,Ltd.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Hubei Co-Formula Material Tech Co., Ltd.	58
Zhengzhou Alfa Chemical Co.,Ltd	58

View Lastest Price from (TERT-BUTYLDIMETHYLSILYLOXY)ACETALDEHYDE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-07-02	(TERT-BUTYLDIMETHYLSILYLOXY)ACETALDEHYDE 102191-92-4	US $0.00 / KG	1KG	98%	1000KG /month	Shanghai Daken Advanced Materials Co.,Ltd
2021-07-02	(tert-Butyldimethylsilyloxy)acetaldehyde 102191-92-4	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd
2019-12-27	(TERT-BUTYLDIMETHYLSILYLOXY)ACETALDEHYDE 102191-92-4	US $1.00 / KG	1KG	99%	200kg	Career Henan Chemical Co

(TERT-BUTYLDIMETHYLSILYLOXY)ACETALDEHYDE
102191-92-4
US $0.00 / KG
98%
Shanghai Daken Advanced Materials Co.,Ltd

(tert-Butyldimethylsilyloxy)acetaldehyde
102191-92-4
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

(TERT-BUTYLDIMETHYLSILYLOXY)ACETALDEHYDE
102191-92-4
US $1.00 / KG
99%
Career Henan Chemical Co

(TERT-BUTYLDIMETHYLSILYLOXY)ACETALDEHYDE Spectrum

(TERT-BUTYLDIMETHYLSILYLOXY)ACETALDEHYDE(102191-92-4)¹HNMR

102191-92-4((TERT-BUTYLDIMETHYLSILYLOXY)ACETALDEHYDE)Related Search:

3-TRIMETHYLSILYLPROPYNAL 2-(ALLYLDIMETHYLSILYL)PYRIDINE 1-(TERT-BUTYLDIMETHYLSILYLOXY)-2-PROPANONE (TERT-BUTYLDIMETHYLSILYLOXY)ACETALDEHYDE (+)-(3R)-3-[(TERT-BUTYL(DIMETHYL)SILYL)OXY]DIHYDROFURAN-2(3H)-ONE

(-)-(3S)-3-([TERT-BUTYL(DIMETHYL)SILYL]OXY)-5-HYDROXYPENTAN-2-ONE ETHYL (S)-(-)-2-(TERT-BUTYLDIMETHYLSILYLOXY)PROPIONATE 2-(TERT-BUTYLDIMETHYLSILYLOXY)CYCLOHEXA& THYMIDINE GLYCOL CEP Ethyl [(tert-Butyldimethylsilyl)oxy]acetate

(-)-(3S)-3-([TERT-BUTYL(DIMETHYL)SILYL]OXY)DIHYDROFURAN-2(3H)-ONE 2-(TERT-BUTYL-DIMETHYL-SILANYLOXY)-PROPIONALDEHYDE AKOS 91264 RARECHEM AL BE 0828 2-(tert-Butyl-dimethylsilanyloxy)-1-(4-fluorophenyl)-ethanone

(6S)-2-BENZYL-6-(TERT-BUTYLDIMETHYLSILYLOXY)CYCLOHEXANONE (S)-3-(TERT-BUTYLDIMETHYLSILYLOXY)PIPERIDIN-2-ONE

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(tert-ButyldiMethylsilyloxy)acetaldehyde (tert-ButyldiMethylsilyloxy)acetaldehyde 90% (tert-Butyldimethylsiloxy)acetaldehyde,90% 2-(tert-butyldimethylsilyloxy)acetaldehyde Acetaldehyde,2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]- (tert-Butyl-dimethyl-silanyloxy)-acetaldehyde 2-(Tert-Butyldimethylsiloxy)acetaldehyde (TERT-BUTYLDIMETHYLSILYLOXY)ACETALDEHYDE T-BUTYLDIMETHYLSILOXYACETALDEHYDE T-BUTYLDIMETHYLSILYLOXYACETALDEHYDE (TERT-BUTYLDIMETHYLSILYLOXY)ACETALDEHYDE,97% DIMETHYL-TERT-BUTYLSILYLOXYACETALDEHYDE t-BUTYLDIMETHYLSILOXYACETALDEHYDE,90% {[Dimethyl(2-methyl-2-propanyl)silyl]oxy}acetaldehyde tert-butyl-(2-methyl-1-oxopropan-2-yl)oxysilicon oxy)acetaL DK447 DKFELEX0096 (tert-Butyldimethylsilyloxy)acetaldehyde 102191-92-4 CH33CSiCH32OCH2CHO Organic Building Blocks C8 Carbonyl Compounds Aldehydes Building Blocks Pyridines ,Halogenated Heterocycles Aldehydes C8 Carbonyl Compounds