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ChemicalBook >> CAS DataBase List >>2-CHLORO-4-HYDROXY-BENZOIC ACID METHYL ESTER

2-CHLORO-4-HYDROXY-BENZOIC ACID METHYL ESTER

2-CHLORO-4-HYDROXY-BENZOIC ACID METHYL ESTER Structure
2-CHLORO-4-HYDROXY-BENZOIC ACID METHYL ESTER structure
CAS No.
104253-44-3
Chemical Name:
2-CHLORO-4-HYDROXY-BENZOIC ACID METHYL ESTER
Synonyms
RARECHEM AL BF 0717;METHYL 2-CHLORO-4-HYDROXYBENZOATE;2-CHLORO-4-HYDROXY-BENZOIC ACID METHYL ESTER;Benzoic acid, 2-chloro-4-hydroxy-, methyl ester;2-Chloro-4-hydroxy-benzoic acid methyl ester≥ 99% (GC)
CBNumber:
CB6452966
Molecular Formula:
C8H7ClO3
Molecular Weight:
186.59
MDL Number:
MFCD04117954
MOL File:
104253-44-3.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:41
Product description Number Pack Size Price
Methyl2-Chloro-4-hydroxybenzoate M340458 500mg $175
Methyl 2-chloro-4-hydroxybenzoate 95+% 119052 1g $324
2-Chloro-4-hydroxybenzoic acid methyl ester FC70262 2g $50
2-Chloro-4-hydroxy-benzoic acid methyl ester 98% OR913032 1g $94
2-Chloro-4-hydroxybenzoic acid methyl ester FC70262 5G $100
More product size
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2-CHLORO-4-HYDROXY-BENZOIC ACID METHYL ESTER Properties

Boiling point 298.3±20.0 °C(Predicted)
Density 1.354±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka 7.39±0.18(Predicted)
Appearance Light yellow to brown Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338
HS Code  2918290090

2-CHLORO-4-HYDROXY-BENZOIC ACID METHYL ESTER price More Price(26)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC M340458 Methyl2-Chloro-4-hydroxybenzoate 104253-44-3 500mg $175 2021-12-16 Buy
Matrix Scientific 119052 Methyl 2-chloro-4-hydroxybenzoate 95+% 104253-44-3 1g $324 2021-12-16 Buy
Biosynth Carbosynth FC70262 2-Chloro-4-hydroxybenzoic acid methyl ester 104253-44-3 2g $50 2021-12-16 Buy
Apolloscientific OR913032 2-Chloro-4-hydroxy-benzoic acid methyl ester 98% 104253-44-3 1g $94 2021-12-16 Buy
Biosynth Carbosynth FC70262 2-Chloro-4-hydroxybenzoic acid methyl ester 104253-44-3 5G $100 2021-12-16 Buy
Product number Packaging Price Buy
M340458 500mg $175 Buy
119052 1g $324 Buy
FC70262 2g $50 Buy
OR913032 1g $94 Buy
FC70262 5G $100 Buy

2-CHLORO-4-HYDROXY-BENZOIC ACID METHYL ESTER Chemical Properties,Uses,Production

Chemical Properties

Tan crystalline powder

Synthesis

Methanol

67-56-1

2-Chloro-4-hydroxybenzoic acid

56363-84-9

2-CHLORO-4-HYDROXY-BENZOIC ACID METHYL ESTER

104253-44-3

General procedure for the synthesis of methyl 2-chloro-4-hydroxybenzoate from methanol and 2-chloro-4-hydroxybenzoic acid: sulfoxide chloride (SOCl2, 1.5 mL) was slowly added to a solution of methanol (10 mL) containing 2-chloro-4-hydroxybenzoic acid (5 g, 0.03 mol). The reaction mixture was gradually heated from room temperature to reflux temperature and reacted under reflux conditions for 12 hours. Upon completion of the reaction, the solvent was removed by concentration under reduced pressure to afford the target product methyl 2-chloro-4-hydroxybenzoate (Compound 132A, red solid, 5.4 g, 100% yield). The structure of the product was confirmed by 1H NMR (400 MHz, DMSO-d6): δ 10.71 (s, 1H), 7.84-7.71 (m, 1H), 6.91 (d, J = 2.4 Hz, 1H), 6.82 (dd, J = 2.4, 8.7 Hz, 1H), 3.79 (s, 3H).

References

[1] Patent: EP3293177, 2018, A1. Location in patent: Paragraph 0332; 0333
[2] Patent: EP1764360, 2007, A1. Location in patent: Page/Page column 176-177
[3] Patent: WO2017/84629, 2017, A1. Location in patent: Paragraph 00316
[4] Patent: WO2017/84630, 2017, A1. Location in patent: Paragraph 00648
[5] Patent: WO2008/157330, 2008, A1. Location in patent: Page/Page column 87

2-CHLORO-4-HYDROXY-BENZOIC ACID METHYL ESTER synthesis

67-56-1
56363-84-9
104253-44-3
Synthesis of 2-CHLORO-4-HYDROXY-BENZOIC ACID METHYL ESTER from Methanol and 2-Chloro-4-hydroxybenzoic acid

2-CHLORO-4-HYDROXY-BENZOIC ACID METHYL ESTER Preparation Products And Raw materials

Raw materials

4-Amino-2-chlorobenzoic acid 2-CHLORO-4-HYDROXYBENZONITRILE 2-Chloro-4-hydroxybenzoic acid Methanol

Preparation Products

2-CHLORO-4-HYDROXY-BENZOIC ACID METHYL ESTER Suppliers

Global( 93)Suppliers
Supplier Tel Email Country ProdList Advantage
Accela ChemBio Inc. 		+1-858-6993322 info@accelachem.com United States 21193 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		+8613580539051 joe@yuhengpharm.com CHINA 21142 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30227 58
Changzhou Anxuan Chemical Co., Ltd 		+86-0519-89882563 +86-18961279162 andy@anxuanchem.com China 4327 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418684 +8618949823763 sales@tnjchem.com China 25356 58
Aromsyn Co., Ltd. 		+86-0571-85585865 +8613336024896 CB@aromsyn.com China 19183 58
Hebei Chuanghai Biotechnology Co., Ltd 		+8615531151365 mina@chuanghaibio.com China 18126 58
Nanjing Bicbiotechnology Co., Ltd 		+86-2552131256 +86-18251840740 sales@bicbiotech.com China 5994 58
Aladdin Scientific 		tp@aladdinsci.com United States 57505 58
Supplier Advantage
Accela ChemBio Inc. 		58
Alchem Pharmtech,Inc. 		58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		58
Career Henan Chemica Co 		58
Changzhou Anxuan Chemical Co., Ltd 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
Aromsyn Co., Ltd. 		58
Hebei Chuanghai Biotechnology Co., Ltd 		58
Nanjing Bicbiotechnology Co., Ltd 		58
Aladdin Scientific 		58

View Lastest Price from 2-CHLORO-4-HYDROXY-BENZOIC ACID METHYL ESTER manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-CHLORO-4-HYDROXY-BENZOIC ACID METHYL ESTER pictures 2024-10-22 2-CHLORO-4-HYDROXY-BENZOIC ACID METHYL ESTER
104253-44-3
 US $9.20 / KG 1KG 99% Customized Career Henan Chemica Co

2-CHLORO-4-HYDROXY-BENZOIC ACID METHYL ESTER Spectrum

2-CHLORO-4-HYDROXY-BENZOIC ACID METHYL ESTER(104253-44-3)1HNMR2-CHLORO-4-HYDROXY-BENZOIC ACID METHYL ESTER(104253-44-3)1HNMR

104253-44-3(2-CHLORO-4-HYDROXY-BENZOIC ACID METHYL ESTER)Related Search:

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METHYL 2-CHLORO-4-HYDROXYBENZOATE 2-CHLORO-4-HYDROXY-BENZOIC ACID METHYL ESTER RARECHEM AL BF 0717 2-Chloro-4-hydroxy-benzoic acid methyl ester≥ 99% (GC) Benzoic acid, 2-chloro-4-hydroxy-, methyl ester 104253-44-3 Aromatic Esters pharmacetical