ChemicalBook >> CAS DataBase List >>PF-05231023
PF-05231023
- CAS No.
- 1037589-69-7
- Chemical Name:
- PF-05231023
- Synonyms
- PF5231023;PF-5231023;PF 5231023;PF-05231023;mal-PEG2-AZD;Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD;Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD, 10 mM in DMSO;PF-05231023; PF05231023; PF 05231023; PF-5231023; PF5231023; PF 5231023;Mal-amido-PEG-2-C2-amido-Ph-C2-CO-AZD,PROTAC Linkers,MalamidoPEG2C2amidoPhC2COAZD,Inhibitor,Mal amido PEG2 C2 amido Ph C2 CO AZD,inhibit;1H-Pyrrole-1-propanamide, 2,5-dihydro-2,5-dioxo-N-[2-[2-[3-oxo-3-[[4-[3-oxo-3-(2-oxo-1-azetidinyl)propyl]phenyl]amino]propoxy]ethoxy]ethyl]-
- CBNumber:
- CB64677804
- Molecular Formula:
- C26H32N4O8
- Molecular Weight:
- 528.55
- MDL Number:
- MFCD31807610
- MOL File:
- 1037589-69-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-07-27 17:00:41
| Product description | Number | Pack Size | Price |
| Maleimide-PEG2-AZD ≥98% | 20129 | 5mg | $107 |
| Maleimide-PEG2-AZD ≥98% | 20129 | 10mg | $193 |
| Maleimide-PEG2-AZD ≥98% | 20129 | 25mg | $318 |
| Maleimide-PEG2-AZD ≥98% | 20129 | 50mg | $528 |
| Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD ≥98% | CS-0063000 | 1mg | $47 |
| Boiling point | 849.9±65.0 °C(Predicted) |
|---|---|
| Density | 1.345±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:4): 0.2 mg/ml |
| form | A solid |
| pka | 14.34±0.70(Predicted) |
| color | White to off-white |
| FDA UNII | DKL4ESK12F |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501 | |||||||||
| NFPA 704 |
|
PF-05231023 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 20129 | Maleimide-PEG2-AZD ≥98% | 1037589-69-7 | 5mg | $107 | 2026-04-30 | Buy |
| Cayman Chemical | 20129 | Maleimide-PEG2-AZD ≥98% | 1037589-69-7 | 10mg | $193 | 2026-04-30 | Buy |
| Cayman Chemical | 20129 | Maleimide-PEG2-AZD ≥98% | 1037589-69-7 | 25mg | $318 | 2026-04-30 | Buy |
| Cayman Chemical | 20129 | Maleimide-PEG2-AZD ≥98% | 1037589-69-7 | 50mg | $528 | 2026-04-30 | Buy |
| ChemScene | CS-0063000 | Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD ≥98% | 1037589-69-7 | 1mg | $47 | 2026-06-04 | Buy |
PF-05231023 Chemical Properties,Uses,Production
Uses
Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD (Mal-PEG2-AZD) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
in vivo
| Animal Model: | Eight week old Zucker rats[3] |
| Dosage: | 3mg/kg and 10mg/kg |
| Administration: | Subcutaneously twice a week for two weeks |
| Result: | There was no change of BW observed, and food intake was not changed in the treated groups compared to control. Caused a significant decrease of glucose excursion during the oral glucose tolerance test (OGTT) compared to control. |
| Animal Model: | 7-to-8-month-old Akita mice with type 1 diabete model[4] |
| Dosage: | 10 mg/kg |
| Administration: | Intraperitoneally injected; twice a week; for four weeks |
| Result: | Administration improved retinal function in diabetic Akita mice. |
IC 50
PEGs
References
[1] Sonoda J, et al. FGF21-receptor agonists: an emerging therapeutic class for obesity-related diseases. Horm Mol Biol Clin Investig. 2017 May 19;30(2). DOI:10.1515/hmbci-2017-0002
PF-05231023 Preparation Products And Raw materials
Raw materials
Preparation Products
PF-05231023 Suppliers
Global( 39)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +8619957148339 | market18@leapchem.com | China | 24569 | 58 |
| WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. | 17702719238 | sales@sun-shinechem.com | China | 1197 | 64 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 18149758185 | sales-cpd@caerulumpharma.com | China | 3492 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 7999 | 62 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Chunchuang (Wuhan) Technology Co., Ltd | 15727060112 | yutianchun2007@126.com | China | 9855 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 27066 | 58 |
View Lastest Price from PF-05231023 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-27 | Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD
1037589-69-7
|
$46.00-137.00 | 99.83% | 10g | TargetMol Chemicals Inc. |
-
- Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD
1037589-69-7
- $46.00-137.00
- 99.83%
- TargetMol Chemicals Inc.
1037589-69-7(PF-05231023)Related Search:
PF-05231023
PF 5231023
PF-05231023; PF05231023; PF 05231023; PF-5231023; PF5231023; PF 5231023
PF5231023
PF-5231023
1H-Pyrrole-1-propanamide, 2,5-dihydro-2,5-dioxo-N-[2-[2-[3-oxo-3-[[4-[3-oxo-3-(2-oxo-1-azetidinyl)propyl]phenyl]amino]propoxy]ethoxy]ethyl]-
Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD
Mal-amido-PEG-2-C2-amido-Ph-C2-CO-AZD,PROTAC Linkers,MalamidoPEG2C2amidoPhC2COAZD,Inhibitor,Mal amido PEG2 C2 amido Ph C2 CO AZD,inhibit
mal-PEG2-AZD
3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-(2-(2-(3-oxo-3-((4-(3-oxo-3-(2-oxoazetidin-1-yl)propyl)phenyl)amino)propoxy)ethoxy)ethyl)propanamide
Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD, 10 mM in DMSO
1037589-69-7
