ChemicalBook >> CAS DataBase List >>2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile

2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile

CAS No.
93413-76-4
Chemical Name:
2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile
Synonyms
VENLAFAXINE CYNO IMPURITY;forVenlafaxine;Venlafaxine Cyano;Effexor Impurity 28;Venlafaxine Impurity 15;Venlafaxine Impurity 28;Venlafaxine Cyano Impurity;Intermediate of Venlafaxine;Venlafaxine Nitrile Impurity;1-[Cyano-(4-Methoxyphenyl)Meth
CBNumber:
CB6476117
Molecular Formula:
C15H19NO2
Molecular Weight:
245.32
MDL Number:
MFCD06658142
MOL File:
93413-76-4.mol
MSDS File:
SDS
Last updated:2026-07-09 20:17:37
Product description Number Pack Size Price
(1-Hydroxycyclohexyl)(4-methoxyphenyl)acetonitrile >98.0%(HPLC)(N) H1303 1g $116
(1-Hydroxycyclohexyl)(4-methoxyphenyl)acetonitrile >98.0%(HPLC)(N) H1303 5g $349
(1-Hydroxycyclohexyl)-(4-methoxyphenyl)acetonitrile FH152714 500mg $900
(1-Hydroxycyclohexyl)-(4-methoxyphenyl)acetonitrile FH152714 5000mg $900
(1-Hydroxycyclohexyl)-(4-methoxyphenyl)acetonitrile FH152714 250mg $900
More product size

2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile Properties

Melting point 121-123°C
Boiling point 410.1±25.0 °C(Predicted)
Density 1.142±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,2-8°C
solubility soluble in Methanol
form powder to crystal
pka 13.80±0.20(Predicted)
color White to Almost white
CAS DataBase Reference 93413-76-4(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319
Precautionary statements  P261-P264-P270-P271-P280-P301+P312+P330-P302+P352+P312+P362+P364-P304+P340+P312-P305+P351+P338+P337+P313-P501
HS Code  2926.90.4850

2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile price More Price(30)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical H1303 (1-Hydroxycyclohexyl)(4-methoxyphenyl)acetonitrile >98.0%(HPLC)(N) 93413-76-4 1g $116 2023-06-20 Buy
TCI Chemical H1303 (1-Hydroxycyclohexyl)(4-methoxyphenyl)acetonitrile >98.0%(HPLC)(N) 93413-76-4 5g $349 2023-06-20 Buy
Biosynth FH152714 (1-Hydroxycyclohexyl)-(4-methoxyphenyl)acetonitrile 93413-76-4 500mg $900 2026-06-04 Buy
Biosynth FH152714 (1-Hydroxycyclohexyl)-(4-methoxyphenyl)acetonitrile 93413-76-4 5000mg $900 2026-06-04 Buy
Biosynth FH152714 (1-Hydroxycyclohexyl)-(4-methoxyphenyl)acetonitrile 93413-76-4 250mg $900 2026-06-04 Buy
Product number Packaging Price Buy
H1303 1g $116 Buy
H1303 5g $349 Buy
FH152714 500mg $900 Buy
FH152714 5000mg $900 Buy
FH152714 250mg $900 Buy

2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile Chemical Properties,Uses,Production

Synthesis

A mixture of p-methoxyphenylacetonitrile 36 (100 g, 0.68 mol), 10% aqueous NaOH solution (100 ml, 0.25 mol) and TBAHSO4 (5 g, 0.014 mol) was stirred at room temperature for 30 minutes. A dark red colour appeared. To this was added cyclohexanone 34 (67 g, 0.680 mol) in small portions at 0 ºC, with vigorous stirring, in such a way that temperature should not rise above 10 ºC. A white solid was formed within 30 minutes to one hour. The solid was crushed and the reaction mixture was further stirred vigorously at room temperature for one more hour. The solid was filtered, washed with water till neutral to pH paper and air-dried. Crystallization from ethyl acetatepetroleum ether (500:350, v/v) gave a bright white solid (161.66 g).

Chemical Properties

White Powder

Uses

An intermediate in the synthesis of N,O-Didesmethylvenlafaxine, a metabolite of Venlafaxine

108-94-1
93413-76-4
Synthesis of 2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile from Cyclohexanone

2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile Preparation Products And Raw materials

Global( 266)Suppliers
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Capot Chemical Co.,Ltd.
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View Lastest Price from 2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile pictures 2026-07-10 2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile
93413-76-4
1kg 98% 1000kgs Shaanxi Dideu New Materials Co. Ltd
2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile pictures 2025-04-04 2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile
93413-76-4
1KG 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
1-[Cyano-(p-methoxyphenyl)methyl]cyclohexanol pictures 2019-07-06 1-[Cyano-(p-methoxyphenyl)methyl]cyclohexanol
93413-76-4
$8.80 1KG 97%-99% 100kg Career Henan Chemical Co
alpha-(1-Hydroxycyclohexyl)-4-methoxybenzeneacetonitrile 1-(Hydroxycyclohexyl)-(4-Methoxyphenly)Acetonitrlle 1-[(1-CYANO)-1-(4-METHOXYPHENYL)METHYL]CYCLODEXANOL 1-[Cyno-(4-Methoxyphenyl)Methyl]Cyclohexanol(Vf1) 1-HydroxyCyclohexyl-4-MethoxyPhenylAcetonitrile(ForVenlafaxineHcl) forVenlafaxine 1-(cyclohexanol)-(4methoxyphenyl)acetonitrile Intermediate of Venlafaxine 1-[Cyano-(4-Methoxyphenyl)Meth 1-(hydroxycyclohexyl)-(4-methoxyphenyl)acetonitrile (intermediate of venlafaxine) 1-hydroxy cyclohexyl-4-methoxy phenyl acetonitrile (intermediate of venlafaxine hcl) 1-[CYANO-(4-METHOXYPHENYL)METHYL]CYCLOHEXANOL[FOR VENLAFAXINE HCL] 4-Methoxy benzyl cyano cyclohexanol 1-(p-Methoxyphenyl-cyano)-methylcyclohexanol α-(1-Hydroxycyclohexyl)-4-Methoxy-benzeneacetonitrile α-(p-Methoxyphenyl)-α-(1-hydroxycyclohexyl)acetonitrile Venlafaxine Hydroxy Nitrile Impurity Venlafaxine Cyano Impurity Venlafaxine hydroxynitrile impurities Venlafaxine Nitrile Impurity Venlafaxine Impurity 3 (Venlafaxine Hydroxy Nitrile Impurity) D,L-VENLAFAXINE, HYDROCHLORIDE int 3-(1-hydroxycyclohexyl)-2-(4-methoxyphenyl)propanenitrile 1-[(1-CYANO)-1-(4-METHOXYPHENYL)METHYL] CYCLOHEXANOL 1-[CYANO-(P-METHOXYPHENYL)METHYL]CYCLOHEXANOL 1-(CYANO-(4-METHOXY PHENYL) METHYL) CYCLOHEXANOL Venlafaxine Impurity 15 (1-Hydroxycyclohexyl)(4-methoxyphenyl)acetonitrile> Benzeneacetonitrile, α-(1-hydroxycyclohexyl)-4-methoxy- 1-(HYDROXYCYCLOHEXY)-(4-METHOXYPHENLY)ACETONITRLLE 1- [Cyano (P- Methoxyphenyl) Methyl] Cyclohexanol: VNF Stage-I Venlafaxine Impurity 28 2-(1-Hydroxycyclohexyl)-2-(4-methoxypheny)acetonitrile 2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile 1-[Cyano-(4-methoxyphenyl)methyl] cyclohexanol (VENLA-I) Venlafaxine Cyano (1-Hydroxycyclohexyl)(4-methoxyphenyl)acetonitrile, ≥ 98.0% Effexor Impurity 28 1-(4-Methoxyphenyl)-4-hydroxycyclohexanecarbonitrile 1-(4-Methoxyphenyl)-2-(1-hydroxycyclohexyl)acetonitrile VENLAFAXINE CYNO IMPURITY 1-Hydroxy-4-methoxyphenylacetonitrile 93413-76-4 C15H19O2N Medicine intermediate Nitriles API intermediates (intermediate of venlafaxine) (intermediate of venlafaxine hcl) Intermediates & Fine Chemicals Pharmaceuticals