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ChemicalBook >> CAS DataBase List >>[(6S,8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-17-(2-chloroacetyl)-6-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate

[(6S,8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-17-(2-chloroacetyl)-6-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate

[(6S,8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-17-(2-chloroacetyl)-6-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate Structure
[(6S,8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-17-(2-chloroacetyl)-6-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate structure
CAS No.
66852-61-7
Chemical Name:
[(6S,8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-17-(2-chloroacetyl)-6-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate
Synonyms
HalobetasolPropioteImpurity11;9-Chloro halobetasol propionate;Halobetasol Propionate Impurity D;Halobetasol Propionate Impurity 11;Halobetasol Propionate USP Impurity D;Halobetasol Propionate 9-Chloro Analog;-Chloro-9-desfluoroHalobetasol17-Propionate;9α-Chloro-9-desfluoro Halobetasol 17-Propionate;Pregna-1,4-diene-3,20-dione, 9,21-dichloro-6-fluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)-, (6α,11β,16β)-;[(6S,8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-17-(2-chloroacetyl)-6-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate
CBNumber:
CB64798341
Molecular Formula:
C25H31Cl2FO5
Molecular Weight:
501.42
MDL Number:
MOL File:
66852-61-7.mol
MSDS File:
SDS
Last updated:2026-05-28 04:29:47
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[(6S,8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-17-(2-chloroacetyl)-6-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate Properties

Melting point >150°C
Boiling point 599.6±50.0 °C(Predicted)
Density 1.33±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka 12.70±0.70(Predicted)
color Off-White to Beige
InChIKey DRPFKMAMNGPPDJ-QNGYMBKVNA-N
SMILES O([C@@]1([C@H](C[C@@]2([H])[C@]3([H])C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]12C)C)C(=O)CCl)C(=O)CC |&1:1,2,4,6,9,17,19,21,24,r|
FDA UNII 7P6H3332RL

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P280-P305+P351+P338

[(6S,8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-17-(2-chloroacetyl)-6-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 440581 9α-Chloro-9-desfluoro Halobetasol 17-Propionate 66852-61-7 5mg $566 2026-06-03 Buy
Usbiological 440581 9α-Chloro-9-desfluoro Halobetasol 17-Propionate 66852-61-7 10mg $921 2026-06-03 Buy
TRC C368555 9α-Chloro-9-desfluoroHalobetasol17-Propionate 66852-61-7 5mg $900 2021-12-16 Buy
Product number Packaging Price Buy
440581 5mg $566 Buy
440581 10mg $921 Buy
C368555 5mg $900 Buy

[(6S,8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-17-(2-chloroacetyl)-6-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate Chemical Properties, Uses, Production

Uses

9α-Chloro-9-desfluoro Halobetasol 17-Propionate is an impurity of Halobetasol Propionate (H102300); an anti-inflammatory and dermatologic agent commonly used to treat psoriasis.

[(6S,8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-17-(2-chloroacetyl)-6-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate Preparation Products And Raw materials

Raw materials

Preparation Products

[(6S,8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-17-(2-chloroacetyl)-6-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate Suppliers

Global Suppliers ( 17)
Supplier Tel Email Country ProdList Advantage
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 9920 65
Quality Control Solutions Ltd. 0755-66853366 13670046396 orders@qcsrm.com China 18188 56
BOC Sciences 16314854226 info@bocsci.com United States 9909 65
Jinan blalong chemical co. LTD 2710913286@qq.com 1513643261@qq.com China 14227 58
Shaanxi Dideu Medichem Co. Ltd 029-81154043 17391733319 1086@dideu.com China 9970 58
Meng Cheng Technology (Shanghai) Co., LTD 400-820-6829 sales@mitachieve.com China 8857 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44871 58
LangFangshi Zekang Pharma Tech CO.,Itd. 0316-2883536 19333636468 93618484@qq.com China 2818 58
Shanghai Zerui Biotechnology Co., Ltd. 021-54580889 18321124657 1054713992@qq.com China 10598 58
Henan Vcommend Consultrading Co., Ltd. 13393721940 sales@vcommend.com China 9957 58
Supplier Advantage
BOC Sciences 65
Quality Control Solutions Ltd. 56
BOC Sciences 65
Jinan blalong chemical co. LTD 58
Shaanxi Dideu Medichem Co. Ltd 58
Meng Cheng Technology (Shanghai) Co., LTD 58
Energy Chemical 58
LangFangshi Zekang Pharma Tech CO.,Itd. 58
Shanghai Zerui Biotechnology Co., Ltd. 58
Henan Vcommend Consultrading Co., Ltd. 58
[(6S,8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-17-(2-chloroacetyl)-6-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate Halobetasol Propionate Impurity D 9α-Chloro-9-desfluoro Halobetasol 17-Propionate Halobetasol Propionate 9-Chloro Analog -Chloro-9-desfluoroHalobetasol17-Propionate 9-Chloro halobetasol propionate HalobetasolPropioteImpurity11 Halobetasol Propionate Impurity 11 Pregna-1,4-diene-3,20-dione, 9,21-dichloro-6-fluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)-, (6α,11β,16β)- Halobetasol Propionate USP Impurity D 66852-61-7