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H-Lys(Boc)-OH

CAS No.
2418-95-3
Chemical Name:
H-Lys(Boc)-OH
Synonyms
H-LYS(BOC)-OH;LYS(BOC);Lys(Boc)-OH;N6-Boc-L-lysine;(S)-2-AMino-6-((tert-butoxycarbonyl)aMino)hexanoic acid;L-LYSINE(BOC);L-LYS(BOC);Nepsilon L;LYSINE(BOC)-OH;e-BOC-L-lysine.
CBNumber:
CB6485395
Molecular Formula:
C11H22N2O4
Molecular Weight:
246.3
MDL Number:
MFCD00037221
MOL File:
2418-95-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:07
Product description Number Pack Size Price
H-Lys(Boc)-OH ≥95% 359661 5g $667
Nepsilon-(tert-Butoxycarbonyl)-L-lysine >97.0%(T) B1670 1g $37
Nepsilon-(tert-Butoxycarbonyl)-L-lysine >97.0%(T) B1670 5g $105
Nε-Boc-L-lysine B656905 100g $970
Nε-Boc-L-lysine B656905 1g $50
More product size

H-Lys(Boc)-OH Properties

Melting point 250 °C (dec.)(lit.)
alpha 17 º (c=1% in acetic acid)
Boiling point 389.3°C (rough estimate)
Density 1.1313 (rough estimate)
refractive index 18 ° (C=1, AcOH)
storage temp. 2-8°C
solubility Soluble in DMSO
pka 2.53±0.24(Predicted)
form powder to crystal
color White to Almost white
optical activity [α]20/D +18°, c = 1 in acetic acid
Water Solubility Slightly soluble in water.
BRN 2417626
Major Application peptide synthesis
InChI 1S/C11H22N2O4/c1-11(2,3)17-10(16)13-7-5-4-6-8(12)9(14)15/h8H,4-7,12H2,1-3H3,(H,13,16)(H,14,15)/t8-/m0/s1
InChIKey VVQIIIAZJXTLRE-QMMMGPOBSA-N
SMILES CC(C)(C)OC(=O)NCCCC[C@H](N)C(O)=O
CAS DataBase Reference 2418-95-3(CAS DataBase Reference)
UNSPSC Code 12352209
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P280-P301+P312-P362+P364
PPE Eyeshields, Gloves, type N95 (US)
Safety Statements  24/25
WGK Germany  3
HS Code  29241990
Storage Class 11 - Combustible Solids
NFPA 704
1
0 0

H-Lys(Boc)-OH price More Price(39)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 359661 H-Lys(Boc)-OH ≥95% 2418-95-3 5g $667 2026-03-19 Buy
TCI Chemical B1670 Nepsilon-(tert-Butoxycarbonyl)-L-lysine >97.0%(T) 2418-95-3 1g $37 2026-03-19 Buy
TCI Chemical B1670 Nepsilon-(tert-Butoxycarbonyl)-L-lysine >97.0%(T) 2418-95-3 5g $105 2026-03-19 Buy
TRC B656905 Nε-Boc-L-lysine 2418-95-3 100g $970 2021-12-16 Buy
TRC B656905 Nε-Boc-L-lysine 2418-95-3 1g $50 2021-12-16 Buy
Product number Packaging Price Buy
359661 5g $667 Buy
B1670 1g $37 Buy
B1670 5g $105 Buy
B656905 100g $970 Buy
B656905 1g $50 Buy

H-Lys(Boc)-OH Chemical Properties,Uses,Production

Chemical Properties

white crystalline powder

Uses

It is used as therapy to treat recurrent herpes simplex infections.

General Description

H-Lys(Boc)-OH, also known as H-Lys(t-BOC)-OH, is an ε-amino-protected lysine. Its e-amino free lysine could be conjugated to polyurethane surfaces by reaction of the alpha-amino group with the NHS and deprotection. The covalent conjugation was carried out in phosphate-buffered saline (PBS), pH 8.2. Lysine was used to create a plasminogen-binding potentially fibrinolytic surface[1].

References

[1] Chen H , et al. Surfaces having dual fibrinolytic and protein resistant properties by immobilization of lysine on polyurethane through a PEG spacer. Journal of Biomedical Materials Research Part A, 2008; 90A: 940-946.

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

Fmoc-Lys(Boc)-OH

71989-26-9

H-Lys(Boc)-OH

2418-95-3

Step 1. N-alpha-Fluorenylmethoxycarbonyl-N-epsilon-tert-butoxycarbonyl-L-lysine (5 g, 10.7 mmol) was dissolved in dichloromethane (DCM) at room temperature and piperidine (5.5 ml, 53 mmol) was added with stirring. The reaction mixture was stirred continuously for 16 hours at room temperature. Upon completion of the reaction, the reaction mixture was extracted with water, the aqueous phase was combined and concentrated to afford N(e)-Boc-L-lysine (20-3) in 95% yield.

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View Lastest Price from H-Lys(Boc)-OH manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
H-Lys(Boc)-OH pictures 2026-04-24 H-Lys(Boc)-OH
2418-95-3
US $0.00-0.00 / kg 1kg 98% 1T+ Sichuan HongRi Pharma-Tech Co.,Ltd
Ne-Boc-L-lysine pictures 2023-07-27 Ne-Boc-L-lysine
2418-95-3
US $0.00 / kg 1kg 99% 2T/month Chengdu Baishixing Science and Technology Industry Co.,Ltd
Lys(Boc) pictures 2020-01-06 Lys(Boc)
2418-95-3
US $1.00 / g 1g 98% 100KG Sichuan Jiaying Lai Technology Co.,LTD
  • H-Lys(Boc)-OH pictures
  • H-Lys(Boc)-OH
    2418-95-3
  • US $0.00-0.00 / kg
  • 98%
  • Sichuan HongRi Pharma-Tech Co.,Ltd
  • Ne-Boc-L-lysine pictures
  • Ne-Boc-L-lysine
    2418-95-3
  • US $0.00 / kg
  • 99%
  • Chengdu Baishixing Science and Technology Industry Co.,Ltd
  • Lys(Boc) pictures
  • Lys(Boc)
    2418-95-3
  • US $1.00 / g
  • 98%
  • Sichuan Jiaying Lai Technology Co.,LTD
(S)-2-AMino-6-((tert-butoxycarbonyl)aMino)hexanoic acid L-Lysine,N6-[(1,1-diMethylethoxy)carbonyl]- H-Lys(Boc)-OH >=95% Nε-Boc-L-Lysine≥ 98% (HPLC) Ne-Boc-L-lysine Nε-Boc-L-lysine N-epsilon-tert-Butoxycarbonyl-L-lysine Nepsilon-Boc-L-lysine H-Lys(Boc)-OH N6-Boc-L-lysine N-EPSILON-(TERT-BUTOXYCARBONYL)-L-LYSINE 97% N-epsilon-Boc-L-lysine,99% e-BOC-L-lysine. L-LYS(BOC) N-EPSILON-T-BUTYLOXYCARBONYL-L-LYSINE Ne-Boc-L-lysine BOC-L-LYSINE extrapure Nepsilon-BOC-L-Lysine,97% (2S)-2-Amino-6-(tert-butoxycarbonylamino)hexanoic acid epsilon-tert-butyloxycarbonyl-lysine LYSINE(BOC)-OH H-LYS(BOC)-OH H-L-LYS(BOC)-OH N-ALPHA-T-BOC-L-LYS N-EPSILON-(TERT-BUTOXYCARBONYL)-L-LYSINE N-EPSILON-TERT-BUTYLOXYCARBONYL-L-LYSINE NEPSILON-BOC-L-LYSINE N-EPSILON-T-BUTOXYCARBONYL-L-LYSINE N-EPSILON-T-BOC-L-LYSINE Nepsilon L L-Lysine, N6-[(1,1-dimethylethoxy)carbonyl]- Ne-Boc-L-lysine USP/EP/BP (2S)-2-azaniumyl-6-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoate H-Lys(Boc)-OH 98% Lys(Boc)-OH L-LYSINE(BOC) LYS(BOC) 2418-95-3 2418-95-1 418-95-3 CH33COCONHCH24CHNH2COOH Specialty Synthesis Amino Acid Derivatives Lysine Peptide Synthesis Boc-Amino Acids Protected & Labeled Amino Acids Amino Acids (N-Protected) Lysine [Lys, K] Amino Acids and Derivatives Amino Acids (N-Protected) Biochemistry Boc-Amino Acids Boc-Amino acid series Amino Acids