CSTA antibody

CAS No.
Chemical Name:
CSTA antibody
Synonyms
CSTA antibody;Rabbit Polyclonal CSTA Antibody
CBNumber:
CB65619890
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file

CSTA antibody Chemical Properties,Uses,Production

Applications

The antibody has been tested by ELISA, Western blot analysis, Flow cytometry and ICC/IF to assure specificity and reactivity.

Immunogen

Anti-human CSTA mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CSTA protein 1-98 amino acids purified from E. coli.

Background

Cystatin-A is the intracellular inhibitor of cysteine proteinase cathepsin B (CatB) and belongs to family 1 of the cystatin superfamily of inhibitor proteins. CSTA is a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. It has been proposed that extracellular CatB together with other classes of proteinases are all subjected to a cascade-like manner of activation. CatB and its inhibitor Cystatin-A are involved in degradation of extracellular matrix proteins during tissue remodeling. CSTA is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Cystatin-A has been reported to be found in high concentrations in epithelial cells, polymorphonuclear leukocytes and lymphoid tissue. Stefins may be used as prognostic and diagnostic tools for cancer.

CSTA antibody Preparation Products And Raw materials

Raw materials

Preparation Products

CSTA antibody Suppliers

Global( 41)Suppliers
Supplier Tel Email Country ProdList Advantage
Hubei Ipodix Biotechnology Co.,Ltd. 18007124176 19384116026 2706668885@qq.com China 4987 58
Hubei Serenity BioSolutions Co., Ltd. 027-19371278702 18008634902 19384116026@163.com China 3008 58
CSTA antibody Rabbit Polyclonal CSTA Antibody