HOP Antibody

CAS No.
Chemical Name:
HOP Antibody
Synonyms
HOP Antibody
CBNumber:
CB65635272
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file

HOP Antibody Chemical Properties, Uses, Production

Source

Rabbit

Reactivity

Human;Mouse;Rat;Monkey

Background

HOP, also known as stress-induced phospho protein 1, is a co-chaperone to the major heat shock proteins, Hsp70 and Hsp90, and appears in early receptor complexes. Through mutual binding to both Hsp70 and Hsp90, Hop functions as an adaptor that can integrate Hsp70 and Hsp90 interactions. HOP is an abundant and highly conserved protein which is composed of three tetratricopeptide repeat domains and two DP repeat domains, whose function has not been fully resolved.

References

[1] Smith, D.F. et al. (1993) Mol Cell Biol 13, 869-76.
[2] Smith, D.F. (1993) Mol Endocrinol 7, 1418-29.
[3] Chen, S. and Smith, D.F. (1998) J Biol Chem 273, 35194-200.
[4] Nelson, G.M. et al. (2003) Cell Stress Chaperones 8, 125-33.
[5] Carrigan, P.E. et al. (2005) J Biol Chem 280, 8906-11.

HOP Antibody Preparation Products And Raw materials

Raw materials

Preparation Products

HOP Antibody