RHOB antibody
- CAS No.
- Chemical Name:
- RHOB antibody
- Synonyms
- RHOB antibody
- CBNumber:
- CB65692183
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
RHOB antibody price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biorbyt Ltd | orb194901 | RHOB Antibody | 50μl | $260 | 2026-05-06 | Buy | |
| Biorbyt Ltd | orb194901 | RHOB Antibody | 100μl | $360 | 2026-05-06 | Buy | |
| Biorbyt Ltd | orb158286 | Rho B antibody Affinity purified by Protein A | 100μg | $421.6 | 2021-12-16 | Buy | |
| Biorbyt Ltd | orb158286 | Rho B antibody Affinity purified by Protein A | 200μg | $673.2 | 2021-12-16 | Buy |
RHOB antibody Chemical Properties,Uses,Production
Source
Rabbit
Reactivity
Human;Mouse;Rat;Monkey
Background
Rho family small GTPases, including Rho, Rac and cdc42, act as molecular switches, regulating processes such as cell migration, adhesion, proliferation and differentiation. They are activated by guanine nucleotide exchange factors, which catalyze the exchange of bound GDP for GTP, and inhibited by GTPase activating proteins, which catalyze the hydrolysis of GTP to GDP. A third level of regulation is provided by the stoichiometric binding of Rho GDP dissociation inhibitor. RhoA, RhoB and RhoC are highly homologous, but appear to have divergent biological functions. Carboxy-terminal modifications and differences in subcellular localization allow these three proteins to respond to and act on distinct signaling molecules.RhoB functions in the regulation of cell shape, migration and adhesion. RhoB activity has also been shown to play a role in protein trafficking and in CXCR2-mediated chemotaxis. Inhibition of RhoB activity downstream of PKCι influences the degree of invasion and migration by glioblastoma cells, and RhoB expression has a negative affect on tumor growth in ovarian cancer.
References
[1] DerMardirossian, C. and Bokoch, G.M. (2005) Trends Cell Biol 15, 356-63.
[2] Wennerberg, K. and Der, C.J. (2004) J Cell Sci 117, 1301-12.
[3] Wheeler, A.P. and Ridley, A.J. (2004) Exp Cell Res 301, 43-9.
[4] Wheeler, A.P. and Ridley, A.J. (2007) Exp Cell Res 313, 3505-16.
[5] Sandilands, E. et al. (2007) J Cell Sci 120, 2555-64.
[6] Neel, N.F. et al. (2007) J Cell Sci 120, 1559-71.
[7] Baldwin, R.M. et al. (2008) Oncogene 27, 3587-3595.
[8] Couderc, B. et al. (2008) Cancer Gene Ther 15, 456-464.
RHOB antibody Preparation Products And Raw materials
Raw materials
Preparation Products
RHOB antibody Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing Anyan Biological Technology Co., Ltd. | 025-52151215 13915956535 13915956535 | 570945402@qq.com | China | 9733 | 58 |
| Hubei Serenity BioSolutions Co., Ltd. | 027-19371278702 18008634902 | 19384116026@163.com | China | 3008 | 58 |
| Supplier | Advantage |
|---|---|
| Nanjing Anyan Biological Technology Co., Ltd. | 58 |
| Hubei Serenity BioSolutions Co., Ltd. | 58 |
