ChemicalBook >> CAS DataBase List >>2,3,10-trimethoxy-5,8,13,13a-tetrahydro-6H-isoquinolino[3,2-a]isoquinolin-9-yl 3-fluorobenzenesulfonate

2,3,10-trimethoxy-5,8,13,13a-tetrahydro-6H-isoquinolino[3,2-a]isoquinolin-9-yl 3-fluorobenzenesulfonate

2,3,10-trimethoxy-5,8,13,13a-tetrahydro-6H-isoquinolino[3,2-a]isoquinolin-9-yl 3-fluorobenzenesulfonate structure

CAS No.: 1233353-86-0

Chemical Name:: 2,3,10-trimethoxy-5,8,13,13a-tetrahydro-6H-isoquinolino[3,2-a]isoquinolin-9-yl 3-fluorobenzenesulfonate

Synonyms: PCSK9-IN-29;Benzenesulfonic acid, 3-fluoro-, 5,8,13,13a-tetrahydro-2,3,10-trimethoxy-6H-dibenzo[a,g]quinolizin-9-yl ester

CBNumber:: CB65832264

Molecular Formula:: C26H26FNO6S

Molecular Weight:: 499.55

MDL Number:

MOL File:: 1233353-86-0.mol

MSDS File:: SDS

Last updated:2025-04-17 18:22:24

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2,3,10-trimethoxy-5,8,13,13a-tetrahydro-6H-isoquinolino[3,2-a]isoquinolin-9-yl 3-fluorobenzenesulfonate Properties

Boiling point	641.4±55.0 °C(Predicted)
Density	1.40±0.1 g/cm3(Predicted)
pka	6.15±0.20(Predicted)
form	Solid
color	Off-white to light yellow

2,3,10-trimethoxy-5,8,13,13a-tetrahydro-6H-isoquinolino[3,2-a]isoquinolin-9-yl 3-fluorobenzenesulfonate price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-1180879	PCSK9-IN-29 99.44%	1233353-86-0	5mg	$173	2026-06-04	Buy
ChemScene	CS-1180879	PCSK9-IN-29 99.44%	1233353-86-0	10mg	$277	2026-06-04	Buy
ChemScene	CS-1180879	PCSK9-IN-29 99.44%	1233353-86-0	25mg	$555	2026-06-04	Buy
ChemScene	CS-1180879	PCSK9-IN-29 99.44%	1233353-86-0	50mg	$888	2026-06-04	Buy
ChemScene	CS-1180879	PCSK9-IN-29 99.44%	1233353-86-0	100mg	$1408	2026-06-04	Buy

Product number	Packaging	Price	Buy
CS-1180879	5mg	$173	Buy
CS-1180879	10mg	$277	Buy
CS-1180879	25mg	$555	Buy
CS-1180879	50mg	$888	Buy
CS-1180879	100mg	$1408	Buy

2,3,10-trimethoxy-5,8,13,13a-tetrahydro-6H-isoquinolino[3,2-a]isoquinolin-9-yl 3-fluorobenzenesulfonate Chemical Properties, Uses, Production

Uses

PCSK9-IN-29 is a lipid-lowering agent. PCSK9-IN-29 can increase low-density lipoprotein receptor (LDLR) protein expression and decrease PCSK9 protein expression in hepG2 cells. PCSK9-IN-29 can reduce the levels of serum LDL-C, TC, and liver enzyme ALT in crab eating macaques fed a high-fat diet, lower body weight and fat, and increase bone mineral content. PCSK9-IN-29 can be used for research on non-alcoholic fatty liver disease and obesity[1].

References

[1] Liu, Jing Wen, et al. Compounds, compositions and methods for treating NASH, NAFLD and obesity. China, CN115279755A. 2022-11-01.

2,3,10-trimethoxy-5,8,13,13a-tetrahydro-6H-isoquinolino[3,2-a]isoquinolin-9-yl 3-fluorobenzenesulfonate Preparation Products And Raw materials

Raw materials

Preparation Products

2,3,10-trimethoxy-5,8,13,13a-tetrahydro-6H-isoquinolino[3,2-a]isoquinolin-9-yl 3-fluorobenzenesulfonate Suppliers

Global Suppliers ( 3)

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Beckham Medical Technology Co., Ltd	13816613772	huahero21@sina.com	China	2995	55
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131885	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58

Supplier	Advantage
Shanghai Beckham Medical Technology Co., Ltd	55
Amadis Chemical Company Limited	58
TargetMol Chemicals Inc.	58

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Benzenesulfonic acid, 3-fluoro-, 5,8,13,13a-tetrahydro-2,3,10-trimethoxy-6H-dibenzo[a,g]quinolizin-9-yl ester PCSK9-IN-29 1233353-86-0 C26H26FNO6S