PDE1C1 (human, recombinant)
- CAS No.
- Chemical Name:
- PDE1C1 (human, recombinant)
- Synonyms
- PDE1C1 (human, recombinant)
- CBNumber:
- CB66198044
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
PDE1C1 (human, recombinant) Chemical Properties, Uses, Production
Description
Phosphodiesterase 1C (PDE1C) is a calcium/calmodulin-dependent PDE that hydrolyzes cAMP and cGMP.1,2 Alternative splicing of PDE1C produces three isoforms that exhibit isoform-specific tissue distribution and domain structure.1 PDE1C isoforms all contain a calcium/calmodulin binding region and a PDE catalytic domain but vary in carboxyterminal length.3 PDE1C1 is a 72 kDa isoform that is primarily expressed in the heart and brain but is also expressed in the lungs, uterus, and testes. PDE1C1 is expressed in MAA human malignant melanoma cells.4 Hippocampal PDE1C1 expression is increased in aged rats.5 Cayman’s PDE1C1 (human, recombinant) protein consists of 871 amino acids and has a calculated molecular weight of 100 kDa.WARNING This product is not for human or veterinary use.
