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12(S)-HPEPE

CAS No.
103239-14-1
Chemical Name:
12(S)-HPEPE
Synonyms
12(S)-HPEPE;HDMYXONNVAOHFR-UOLHMMFFSA-N;12(S)-HpEPE(solution in ethanol);12(S)-hydroperoxy-5(Z),8(Z),10(E),14(Z),17(Z)-EPA;12S-HYDROPEROXY-5Z,8Z,10E,14Z,17Z-EICOSAPENTAENOIC ACID;5,8,10,14,17-Eicosapentaenoic acid, 12-hydroperoxy-, (5Z,8Z,10E,12S,14Z,17Z)-
CBNumber:
CB6687498
Molecular Formula:
C20H30O4
Molecular Weight:
334.45
MDL Number:
MFCD00065835
MOL File:
103239-14-1.mol
MSDS File:
SDS
Last updated:2026-04-21 10:31:43
Product description Number Pack Size Price
12(S)-HpEPE ≥96% 42550 25μg $222
12(S)-HpEPE ≥96% 42550 50μg $399
12(S)-HpEPE ≥96% 42550 100μg $707
12(S)-HpEPE ≥96% 42550 25μg $201
12(S)-HpEPE ≥96% 42550 50μg $362

12(S)-HPEPE Properties

storage temp. Store at -20°C
solubility 0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS02
Signal word  Danger
NFPA 704
3
0 0

12(S)-HPEPE price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 42550 12(S)-HpEPE ≥96% 103239-14-1 25μg $222 2026-04-30 Buy
Cayman Chemical 42550 12(S)-HpEPE ≥96% 103239-14-1 50μg $399 2026-04-30 Buy
Cayman Chemical 42550 12(S)-HpEPE ≥96% 103239-14-1 100μg $707 2026-04-30 Buy
Cayman Chemical 42550 12(S)-HpEPE ≥96% 103239-14-1 25μg $201 2024-03-01 Buy
Cayman Chemical 42550 12(S)-HpEPE ≥96% 103239-14-1 50μg $362 2024-03-01 Buy
Product number Packaging Price Buy
42550 25μg $222 Buy
42550 50μg $399 Buy
42550 100μg $707 Buy
42550 25μg $201 Buy
42550 50μg $362 Buy

12(S)-HPEPE Chemical Properties,Uses,Production

Description

12(S)-HpEPE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 12-lipoxygenase on eicosapentaenoic acid. Although the biological activities of 12(S)-HpEPE have not been well characterized, it is expected to behave similarly to 12(S)-HpETE (Catalog No. 44570).

Uses

12(S)-HPEPE is a lipoxygenase product and an intermediate metabolite that leads to downregulation of PGHS-2 and has potential anti-inflammatory activity. 12(S)-HPEPE reduces interleukin 1h (IL-1h)-induced PGHS-2 expression in human lung microvascular endothelial cells[1].

Definition

ChEBI: 12(S)-HpEPE is a 12-HPEPE in which the hydroperoxy group at positions 12 has S-configuration. It has a role as a human xenobiotic metabolite. It is a conjugate acid of a 12(S)-HpEPE(1-).

References

[1] Ait-Said F, et al. Inhibition by eicosapentaenoic acid of IL-1beta-induced PGHS-2 expression in human microvascular endothelial cells: involvement of lipoxygenase-derived metabolites and p38 MAPK pathway. Biochim Biophys Acta. 2003 Feb 20;1631(1):77-84. DOI:10.1016/s1388-1981(02)00358-x

12(S)-HPEPE Preparation Products And Raw materials

Raw materials

Preparation Products

12(S)-HPEPE Suppliers

Global( 35)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32467 58
Yichang Zhongyitai Trading Co., Ltd. 0717-6449896 13886658719 root@zhongyitai.com China 1978 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6777 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11218 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8140 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24960 58
Shanghai Yiyan Biotechnology Co. , Ltd. 021-69985186 13611928337 3427709316@qq.com China 7982 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11972 58
SHANGHAI ZZBIO CO., LTD. 021-58979353 13391016096 tech@zzbioco.com China 12064 58
Cayman Chemical Company 800-364-9897 sales@caymanchem.com China 6838 58

View Lastest Price from 12(S)-HPEPE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
12(S)-HpEPE pictures 2026-04-20 12(S)-HpEPE
103239-14-1
US $1280.00 / μg 10g TargetMol Chemicals Inc.
  • 12(S)-HpEPE pictures
  • 12(S)-HpEPE
    103239-14-1
  • US $1280.00 / μg
  • TargetMol Chemicals Inc.
12(S)-HPEPE 12S-HYDROPEROXY-5Z,8Z,10E,14Z,17Z-EICOSAPENTAENOIC ACID HDMYXONNVAOHFR-UOLHMMFFSA-N 5,8,10,14,17-Eicosapentaenoic acid, 12-hydroperoxy-, (5Z,8Z,10E,12S,14Z,17Z)- 12(S)-hydroperoxy-5(Z),8(Z),10(E),14(Z),17(Z)-EPA 12(S)-HpEPE(solution in ethanol) 103239-14-1