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Dynorphin A (1-13)

Dynorphin A (1-13) Structure
Dynorphin A (1-13) structure
CAS No.
72957-38-1
Chemical Name:
Dynorphin A (1-13)
Synonyms
Dyn(1-13);YGGFLRRIRPKLK;DYNORPHIN 1-13;ynorphin A (1-13);DYNORPHIN A (1-13);sh-Oligopeptide-71;Dynorphin A1-13【pig】;Dynorphin A(1-13)【pig】;Dynorphin A(1-13)【rat】;DYNORPHIN A(HUMAN, 1-13)
CBNumber:
CB6699152
Molecular Formula:
C75H126N24O15
Molecular Weight:
1603.96
MDL Number:
MFCD00076366
MOL File:
72957-38-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-11 19:39:08
Product description Number Pack Size Price
Dynorphin A Porcine Fragment 1-13 ≥97% (HPLC) D7017 1mg $210
Dynorphin A (1-13) PurifiedbyProteinAaffinitychromatography D9902-02C 400ug $899
Dynorphin A (1-13), porcine PD16951 1mg $178.75
Dynorphin A (Human, 1-13) PDY-4080-V 0.5mg $285.85
Dynorphin A (1-13), porcine PD16951 10mg $225.3
More product size
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Dynorphin A (1-13) Properties

Density 1.39±0.1 g/cm3(Predicted)
RTECS JV7436666
storage temp. Inert atmosphere,Store in freezer, under -20°C
pka 3.31±0.10(Predicted)
form Solid
color White to off-white
Water Solubility Water: ≥ 60 mg/mL (37.41 mM)
Sequence H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-OH
Cosmetics Ingredients Functions ANTI-SEBUM
SKIN PROTECTING
InChIKey OVVIBUHLQIYUEU-JASZZEBFNA-N
FDA UNII VFC23V742Z

SAFETY

Risk and Safety Statements

WGK Germany  3
HS Code  2933998090

Dynorphin A (1-13) price More Price(43)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich D7017 Dynorphin A Porcine Fragment 1-13 ≥97% (HPLC) 72957-38-1 1mg $210 2026-04-30 Buy
Usbiological D9902-02C Dynorphin A (1-13) PurifiedbyProteinAaffinitychromatography 400ug $899 2026-06-03 Buy
Biosynth PD16951 Dynorphin A (1-13), porcine 1mg $178.75 2026-06-04 Buy
Biosynth PDY-4080-V Dynorphin A (Human, 1-13) 72957-38-1 0.5mg $285.85 2026-06-04 Buy
Biosynth PD16951 Dynorphin A (1-13), porcine 10mg $225.3 2026-06-04 Buy
Product number Packaging Price Buy
D7017 1mg $210 Buy
D9902-02C 400ug $899 Buy
PD16951 1mg $178.75 Buy
PDY-4080-V 0.5mg $285.85 Buy
PD16951 10mg $225.3 Buy

Dynorphin A (1-13) Chemical Properties,Uses,Production

Description

Dynorphin A(1-13), a tridecapeptide of the endogenous opioid peptides, has modest effects in reducing mild opiate withdrawal in humans. Previous studies revealed that dynorphin also potentiates the analgesic effect of morphine in morphine-tolerant rats and mice. The therapeutic potential of dynorphin A(1-13) is limited due to extensive metabolism by human metabolic enzymes resulting in an in vivo half-life of less than one minute. Chemical modifications of dynorphin A(1-13), such as N-methylation of Tyr1 and amidation of the C-terminus have been shown to be effective in protecting against the proteolytic enzymes in human plasma[1].

Uses

Porcine dynorphin A (1-13) is a potent, endogenous κ opioid receptor agonist and is antinociceptive at physiological concentrations.

Application

Dynorphin A (1-13) has been used as a test compound in the field asymmetric waveform ion mobility spectrometry coupled to mass spectrometry (FAIMS/IMS/MS).

Biochem/physiol Actions

Dynorphin A (1-13), a bioactive product of dynorphin A displays interaction with N-methyl- D-aspartate (NMDA) as well as with opioid receptors. It elevates intracellular calcium [Ca2+]i level and contributes to the loss of neurons affecting neuronal viability.

in vivo

Dynorphin A (1-13) exposure (33 μM) causes a significant loss in neuronal viability at 4 h with a visible destruction in neuronal morphology seen at 16 h. Exposure to dynorphin A (1-13) causes acute increases in [Ca2+]i in individual neurons similar to increases seen with acute NMDA treatment. Continuous exposure to dynorphin A (1-13) (100 μM) causes a significant loss of neurons over time[1].

IC 50

κ Opioid Receptor/KOR

References

[1] B BRUGOS; G H. Metabolism of dynorphin A(1-13).[J]. Pharmazie, 2004.

Dynorphin A (1-13) synthesis

79598-29-1
72957-38-1
Synthesis of Dynorphin A (1-13) from L-Lysine, N-[(phenylmethoxy)carbonyl]-L-tyrosylglycylglycyl-L-phenylalanyl-L-leucyl-N5-[imino[[(4-methoxy-2,6-dimethylphenyl)sulfonyl]amino]methyl]-L-ornithyl-N5-[imino[[(4-methoxy-2,6-dimethylphenyl)sulfonyl]amino]methyl]-L-ornithyl-L-isoleucyl-N5-[imino[[(4-methoxy-2,6-dimethylphenyl)sulfonyl]amino]methyl]-L-ornithyl-L-prolyl-N6-[(1,1-dimethylethoxy)carbonyl]-L-lysyl-L-leucyl-N6-[(1,1-dimethylethoxy)carbonyl]-, 1,1-dimethylethyl ester

Dynorphin A (1-13) Preparation Products And Raw materials

Raw materials

L-Lysine, N-[(phenylmethoxy)carbonyl]-L-tyrosylglycylglycyl-L-phenylalanyl-L-leucyl-N5-[imino[[(4-methoxy-2,6-dimethylphenyl)sulfonyl]amino]methyl]-L-ornithyl-N5-[imino[[(4-methoxy-2,6-dimethylphenyl)sulfonyl]amino]methyl]-L-ornithyl-L-isoleucyl-N5-[imino[[(4-methoxy-2,6-dimethylphenyl)sulfonyl]amino]methyl]-L-ornithyl-L-prolyl-N6-[(1,1-dimethylethoxy)carbonyl]-L-lysyl-L-leucyl-N6-[(1,1-dimethylethoxy)carbonyl]-, 1,1-dimethylethyl ester

Preparation Products

Dynorphin A (1-13) Suppliers

Global( 184)Suppliers
Supplier Tel Email Country ProdList Advantage
Chengdu Youngshe Chemical Co., Ltd.
+8618108235634 Cecilia@youngshechem.com China 2345 58
Henan Bao Enluo International TradeCo.，LTD
+86-17331933971 deasea125996@gmail.com China 2472 58
Apextide Co Ltd
+8615300650552 info@apextide.com China 91 58
Wuhan Fortuna Chemical Co., Ltd 		+86-27-59207850 info@fortunachem.com China 5990 58
Zibo Hangyu Biotechnology Development Co., Ltd 		+86-0533-2185556 +8615965530500 nickzhang@hangyubiotech.com China 9945 58
Nantong Guangyuan Chemicl Co,Ltd 		+undefined17712220823 admin@guyunchem.com China 615 58
Hangzhou Hyper Chemicals Limited 		+86-0086-57187702781 +8613675893055 info@hyper-chem.com China 310 58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD 		+86-15225627621 +86-13213167925 jiuyitime@fdachem.com China 16512 58
Adachibio Inc. 		+81-8027837258; +8108027837258 sales@adachibio.com Japan 938 58
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29812 58
Supplier Advantage
Chengdu Youngshe Chemical Co., Ltd.
58
Henan Bao Enluo International TradeCo.，LTD
58
Apextide Co Ltd
58
Wuhan Fortuna Chemical Co., Ltd 		58
Zibo Hangyu Biotechnology Development Co., Ltd 		58
Nantong Guangyuan Chemicl Co,Ltd 		58
Hangzhou Hyper Chemicals Limited 		58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD 		58
Adachibio Inc. 		58
career henan chemical co 		58

View Lastest Price from Dynorphin A (1-13) manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Dynorphin A (1-13) pictures 2026-06-25 Dynorphin A (1-13)
72957-38-1
 1g 98%min 1000g WUHAN FORTUNA CHEMICAL CO., LTD
Dynorphin A (1-13) pictures 2026-05-29 Dynorphin A (1-13)
72957-38-1
 1Gram 99%, USP, EP 100KG Hangzhou Hyper Chemicals Limited
Tridecapeptide-1 pictures 2026-05-28 Tridecapeptide-1
72957-38-1
 $500.00 1kg ≥99.00% 1000000 Chengdu Shengnuo Biopharm Co.,Ltd

72957-38-1(Dynorphin A (1-13))Related Search:

DYNORPHIN B (1-13) H-TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-OH LEU-ENKEPHALIN-ARG dynorphin B (1-29) DYNORPHIN B (1-9)
TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-LYS-LEU-LYS-TRP-ASP-ASN-GLN-NH2 Dynorphin A (1-13) L-LEUCYL-L-ALANINE (D-ARG6)-DYNORPHIN A (1-13),[D-ARG6]-DYNORPHIN A (1-13), PORCINE DYNORPHIN A (2-13), PORCINE,DYNORPHIN A (2-13)
dynorphin amide (1-13), Ala(2)-(5-F-Phe)(4)- [D-ALA2]-DYNORPHIN A (1-13) AMIDE,[DALA2] DYNORPHIN A (1-13), AMIDE, PORCINE [DALA2, DARG6] DYNORPHIN A, (1-13), PORCINE,(D-ALA2,D-ARG6)-DYNORPHIN A (1-13) (ARG11,13)-DYNORPHIN A (1-13)-GLY-NH-(CH2)5-NH2,(ARG11,13)-DYNORPHIN A (1-13)-GLY-5-AMINO-PENTYLAMIDE DYNORPHIN A (1-11) AMIDE
DYNORPHIN A (1-10) AMIDE H-LYS-LEU-NH2 LEU-ENKEPHALIN AMIDE

1of4

TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-LYS-LEU-LYS TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-LYS-LEU-LYS 5ACOH 6H2O TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-LYS-LEU-LYS PORCINE YGGFLRRIRPKLK L-TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-LYS-LEU-LYS DYNORPHIN A PORCINE FRAGMENT 1-13 DYNORPHIN A(HUMAN, 1-13) DYNORPHIN A (HUMAN, 1-13) (PORCINE, RAT, BOVINE) DYNORPHIN A (HUMAN, 1-13) (PORCINE, RAT, BOVINE) 5ACOH 6H2O DYNORPHIN A (1-13) DYNORPHIN A (1-13), PORCINE DYNORPHIN 1-13 H-TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-LYS-LEU-LYS-OH DYNORPHIN A (2-13) SYNTHETIC >97% OPIOID AGONIST DYNORPHIN A (1-13) SYNTHETIC >97% OPIOID AGONIST Dynorphin A (1-13) (human, porcine) Porcine dynorphin A(1-13) H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-OH acetate salt dynorphin A, porcine, fragment 1-13 acetate Dyn(1-13) Dynorphin A(1-13)【pig】 Dynorphin A(1-13)【rat】 Dynorphin A1-13【pig】 Dynorphin (1-17), Dynorphin (1-14) Dynphin A (1-13) Acetate Porcine dynorphin A(1-13),Dynorphin A Porcine Fragment 1-13, BR 1-13-Dynorphin A (swine) Dynorphin A (1-13) USP/EP/BP Dynorphin (1-17), Dynorphin (1-13)(net) 1-13-Dynorphin A acetate salt Dynorphin A (1-13), porcine Acetate sh-Oligopeptide-71 Dynorphin A (porcine 1-13) - acetate salt ynorphin A (1-13) 72957-38-1 C75H126N24O15 Dynorphins Peptides Opioid Peptides BioChemical Biochemicals and Reagents Amino Acids and Peptides Opioid receptor and opioid-like receptor peptide DynorphinsPeptides for Cell Biology Dynorphins Neuropeptides Opioid Peptides