IL-11
- CAS No.
- Chemical Name:
- IL-11
- Synonyms
- AGIF;IL-11;RHIL-11;HUMAN AGIF;HUMAN IL-11;IL-11, HUMAN;INTERLEUKIN 11;REC IL-11 (HUMAN);HUMAN INTERLEUKIN-11;INTERLEUKIN-11, HUMAN
- CBNumber:
- CB6699369
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00212208
- MOL File:
- Mol file
| Product description | Number | Pack Size | Price |
| IL-11 human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), suitable for cell culture | SRP3072 | 10 μg | $356 |
| ANTI-IL11 antibody produced in mouse clone 3C6, purified immunoglobulin, buffered aqueous solution | SAB1411909 | 100 μg | $541 |
| Interleukin-11 human >97% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture | I2406 | 5 μg | $330.5 |
| Interleukin 11 | I8433-03 | 25ug | $340 |
| Interleukin 11 | 155347 | 10ug | $350 |
| storage temp. | −20°C |
|---|---|
| form | lyophilized powder |
| color | off-white to yellow |
| biological source | mouse |
| NCI Dictionary of Cancer Terms | IL-11; interleukin-11; rhIL-11 |
| FDA UNII | O14Q7A13PT |
| UNSPSC Code | 12352203 |
| NACRES | NA.41 |
SAFETY
Risk and Safety Statements
| PPE | Eyeshields, Gloves, type N95 (US) |
|---|---|
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
IL-11 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SRP3072 | IL-11 human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), suitable for cell culture | 10 μg | $356 | 2025-07-31 | Buy | |
| Sigma-Aldrich | SAB1411909 | ANTI-IL11 antibody produced in mouse clone 3C6, purified immunoglobulin, buffered aqueous solution | 100 μg | $541 | 2025-07-31 | Buy | |
| Sigma-Aldrich | I2406 | Interleukin-11 human >97% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture | 5 μg | $330.5 | 2025-07-31 | Buy | |
| Usbiological | I8433-03 | Interleukin 11 | 25ug | $340 | 2021-12-16 | Buy | |
| Usbiological | 155347 | Interleukin 11 | 10ug | $350 | 2021-12-16 | Buy |
IL-11 Chemical Properties,Uses,Production
Uses
Interleukin-11 (IL-11) is synthesized by many mesenchymal origin cells like keratinocytes, synoviocytes, fibroblasts, bone marrow stromal cells, osteoblasts, and chondrocytes.
The gene IL-11 (interleukin 11) is mapped to human chromosome 19q13.4. It is a secreted protein.
Biological Activity
Interleukin 11 (IL11) stimulates tumorigenesis in conjunction with angiogenesis of the primary tumor and of metastatic progenies at distant organs. IL-11 signaling is considered as a rate-limiting step for the tumorigenesis in the mucosa of the gastrointestinal tract. Thus, inhibition of IL-11 signaling can be considered as an emerging therapeutic strategy for various cancers. In addition, this protein also performs a protective role by increasing platelet recovery and inflammatory responses, in sepsis patients with thrombocytopenia. Mutation in the gene increases the risk of susceptibility to Hirschsprung disease and multiple sclerosis (MS).
Description
Interleukin-11 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 179 amino acids and having a molecular mass of 19256.29 Dalton.
The IL-11 is purified by proprietary chromatographic techniques.
Source
Escherichia Coli
Background
IL11 is a member of the gp130 family of cytokines. These cytokines drive the assembly of multisubunit receptor complexes, all of which contain at least one molecule of the transmembrane signaling receptor IL6ST (gp130). IL-11 is shown to stimulate the T-cell-dependent development of immunoglobulin-producing B cells. It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells.
IL-11 Preparation Products And Raw materials
Raw materials
Preparation Products
IL-11 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Kanglang Biotechnology Co., Ltd. | 021-61998208 18217752821 | sales@klbio.cn | China | 9621 | 58 |
| GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42934 | 64 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15402 | 60 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 010-50973130 18101056239 | 3193328036@qq.com | China | 29662 | 68 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 17801761073 | 3193328036@qq.com | China | 6338 | 68 |
| Nanjing Meihao Pharmaceutical Technology Co., Ltd. | meitaochem@126.com | meitaochem@126.com | China | 19103 | 58 |
| Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 | 422450190@qq.com | China | 10308 | 58 |
| Shanghai fantai biology science and technology co., ltd | 15601885736 | 2114786541@qq.com | China | 206 | 58 |
| Abmole Bioscience Inc. | 021-50967598 02150967598 | sales@abmole.cn | China | 4494 | 58 |
