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5-Acetamidoindole

5-Acetamidoindole Structure
5-Acetamidoindole structure
CAS No.
7145-71-3
Chemical Name:
5-Acetamidoindole
Synonyms
Nsc74979;5-Acetamidoindole;N-(1H-indol-5-yl)acetaMide;Acetamide, N-1H-indol-5-yl-
CBNumber:
CB6705000
Molecular Formula:
C10H10N2O
Molecular Weight:
174.2
MDL Number:
MFCD01320495
MOL File:
7145-71-3.mol
MSDS File:
SDS
Last updated:2026-09-12 18:54:22
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5-Acetamidoindole Properties

Melting point 117-118 °C(Solv: acetonitrile (75-05-8))
Boiling point 461.2±18.0 °C(Predicted)
Density 1.290±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka 15.59±0.43(Predicted)
Appearance White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2933998090

5-Acetamidoindole price More Price(38)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth HAA14571 N-(1H-Indol-5-yl)acetamide 7145-71-3 1g $1604.8 2026-06-04 Buy
Biosynth HAA14571 N-(1H-Indol-5-yl)acetamide 7145-71-3 10g $5192 2026-06-04 Buy
Apolloscientific OR931441 N-(1H-Indol-5-yl)acetamide 97% 7145-71-3 100mg $33 2026-06-04 Buy
Apolloscientific OR931441 N-(1H-Indol-5-yl)acetamide 97% 7145-71-3 250mg $48 2026-06-04 Buy
Apolloscientific OR931441 N-(1H-Indol-5-yl)acetamide 97% 7145-71-3 1g $86 2026-06-04 Buy
Product number Packaging Price Buy
HAA14571 1g $1604.8 Buy
HAA14571 10g $5192 Buy
OR931441 100mg $33 Buy
OR931441 250mg $48 Buy
OR931441 1g $86 Buy

5-Acetamidoindole Chemical Properties,Uses,Production

Synthesis

5-Aminoindole

5192-03-0

Acetyl chloride

75-36-5

5-ACETAMIDOINDOLE

7145-71-3

General method (10): 5-Aminoindole (1.0 eq.) and triethylamine (3.6 eq.) were dissolved in dichloromethane (10 mL, corresponding to 1.182 mmol of raw material) and acetyl chloride (1.2 eq.) was added slowly. The reaction mixture was stirred at room temperature for 3 hours. After completion of the reaction, the mixture was poured into water and extracted three times with dichloromethane. The organic layers were combined, washed with brine, dried over anhydrous sodium sulfate and concentrated under reduced pressure. Purification by fast silica gel column chromatography using 7:3 hexane/ethyl acetate as eluent afforded 5-acetamidoindole (Intermediate 17A/-(1/-/-indol-5-yl)acetamide, Intermediate 17) as a clear oil (177 mg, 1.016 mmol, 85% yield).1H NMR (400 MHz, CDCl3) δ 8.27 ( bs, 1H), 7.80 (s, 1H), 7.30 (d, J = 8.5 Hz, 2H), 7.20 (dd, J = 8.8, 2.0 Hz, 2H), 6.50 (s, 1H), 2.18 (s, 3H).

References

[1] Patent: WO2016/200339, 2016, A1. Location in patent: Page/Page column 93-94
[2] European Journal of Medicinal Chemistry, 2018, vol. 156, p. 344 - 367

5-Acetamidoindole Preparation Products And Raw materials

Raw materials

5-Aminoindole Acetyl chloride Triethylamine Dichloromethane

Preparation Products

5-Acetamidoindole Suppliers

Global( 45)Suppliers
Supplier Tel Email Country ProdList Advantage
Wuhan TCASChem Technology Co., Ltd. 027-86697669 13986148687 sales@tcaschem.com China 3993 55
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Amatek Scientific Co. Ltd. 0512-56316828 400-867-5858;400-867-5858 info@amateksci.com China 28763 58
Aikon International Limited 025-58859352 15955137747 sales01@aikonchem.com China 16021 58
Cool Pharm, Ltd 021-58581007 18019463053 sales@coolpharm.com China 9999 58
Career Henan Chemica Co +86-0371-86658258 +86-13203830695 laboratory@coreychem.com China 30203 58
Changzhou Kechem Bio-Scientific Co., LTD. 0519-68985668 13685222090 sales@kechem.cn China 26012 58
Shanghai Sunway Pharmaceutical Technology Co.,Ltd. 13611835272 13611835272 mmwang@sunwaypharm.com China 44090 58
Supplier Advantage
Wuhan TCASChem Technology Co., Ltd. 55
Bide Pharmatech Ltd. 60
Shanghai YuanYe Biotechnology Co., Ltd. 60
Amadis Chemical Company Limited 58
Amatek Scientific Co. Ltd. 58
Aikon International Limited 58
Cool Pharm, Ltd 58
Career Henan Chemica Co 58
Changzhou Kechem Bio-Scientific Co., LTD. 58
Shanghai Sunway Pharmaceutical Technology Co.,Ltd. 58

5-Acetamidoindole Spectrum

5-ACETAMIDOINDOLE(7145-71-3)1HNMR

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Nsc74979 N-(1H-indol-5-yl)acetaMide Acetamide, N-1H-indol-5-yl- 5-Acetamidoindole 7145-71-3