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4-Bromo-1-fluoro-2-nitrobenzene

4-Bromo-1-fluoro-2-nitrobenzene Structure
4-Bromo-1-fluoro-2-nitrobenzene structure
CAS No.
364-73-8
Chemical Name:
4-Bromo-1-fluoro-2-nitrobenzene
Synonyms
5-BROMO-2-FLUORONITROBENZENE;2-fluoro-5-bromonitrobenzene;5-Bromo-2-fL;4-Bromo-1-fluoro-2-n;4-Bromo-2-nitrofluorobenzene;4-BROMO-1-FLUORO-2-NITROBENZENE;5-Bromo-2-fluoronitrobenzene98%;1-BROMO-4-FLUORO-3-NITROBENZENE;5-Bromo-2-fluoronitrobenzene 98%;Benzene, 4-bromo-1-fluoro-2-nitro-
CBNumber:
CB6705914
Molecular Formula:
C6H3BrFNO2
Molecular Weight:
220
MDL Number:
MFCD00129165
MOL File:
364-73-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 03:04:47
Product description Number Pack Size Price
4-Bromo-1-fluoro-2-nitrobenzene 96% 539112 25g $197
4-Bromo-1-fluoro-2-nitrobenzene >96.0%(GC) B2075 1g $24
4-Bromo-1-fluoro-2-nitrobenzene >96.0%(GC) B2075 5g $57
4-Bromo-1-fluoro-2-nitrobenzene ≥99%(GC) 46212 25G $20
4-Bromo-1-fluoro-2-nitrobenzene ≥99%(GC) 46212 100G $40
More product size
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4-Bromo-1-fluoro-2-nitrobenzene Properties

Melting point 18-19 °C (lit.)
Boiling point 240-241 °C (lit.)
Density 1.786 g/mL at 25 °C (lit.)
refractive index n20/D 1.575(lit.)
Flash point >230 °F
storage temp. Inert atmosphere,Room Temperature
solubility Difficult to mix.
form Liquid After Melting
color Clear yellow to brownish
BRN 2329084
InChI InChI=1S/C6H3BrFNO2/c7-4-1-2-5(8)6(3-4)9(10)11/h1-3H
InChIKey UQEANKGXXSENNF-UHFFFAOYSA-N
SMILES C1(F)=CC=C(Br)C=C1[N+]([O-])=O
CAS DataBase Reference 364-73-8(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)Skull and Crossbones (GHS06)
GHS07,GHS06
Signal word  Warning
Hazard statements  H315-H319-H302-H312-H331
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P304+P340-P305+P351+P338-P405-P501a
PPE Eyeshields, Gloves
Hazard Codes  Xn,Xi
Risk Statements  36/37/38-20/21/22
Safety Statements  36/37/39-26
RIDADR  2810
WGK Germany  3
Hazard Note  Irritant
HazardClass  6.1
PackingGroup  Ⅲ
HS Code  29049090
Storage Class 10 - Combustible liquids
NFPA 704
0
2 0

4-Bromo-1-fluoro-2-nitrobenzene price More Price(60)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 539112 4-Bromo-1-fluoro-2-nitrobenzene 96% 364-73-8 25g $197 2026-04-30 Buy
TCI Chemical B2075 4-Bromo-1-fluoro-2-nitrobenzene >96.0%(GC) 364-73-8 1g $24 2026-04-30 Buy
TCI Chemical B2075 4-Bromo-1-fluoro-2-nitrobenzene >96.0%(GC) 364-73-8 5g $57 2026-04-30 Buy
Chem-Impex 46212 4-Bromo-1-fluoro-2-nitrobenzene ≥99%(GC) 364-73-8 25G $20 2026-05-19 Buy
Chem-Impex 46212 4-Bromo-1-fluoro-2-nitrobenzene ≥99%(GC) 364-73-8 100G $40 2026-05-19 Buy
Product number Packaging Price Buy
539112 25g $197 Buy
B2075 1g $24 Buy
B2075 5g $57 Buy
46212 25G $20 Buy
46212 100G $40 Buy

4-Bromo-1-fluoro-2-nitrobenzene Chemical Properties,Uses,Production

Chemical Properties

Clear yellow to brownish liquid after melting

Uses

Used in the synthesis of anti-inflammatory agents.1

Uses

4-Bromo-1-fluoro-2-nitrobenzene is used in the synthesis of anti-inflammatory agents.

General Description

4-Bromo-1-fluoro-2-nitrobenzene undergoes Sonogashira reaction with 2-fluoronitrobenzene to afford predominantly the bromo displacement product.

Synthesis

1-Fluoro-2-nitrobenzene

1493-27-2

4-Bromo-1-fluoro-2-nitrobenzene

364-73-8

General procedure for the synthesis of 4-bromo-1-fluoro-2-nitrobenzene from 1-fluoro-2-nitrobenzene: After completion of the reaction, the reaction mixture was cooled to room temperature and slowly poured into ice water. The product 2-fluoro-5-bromonitrobenzene in the aqueous phase was extracted with 200 mL of ethyl acetate, and the organic phases were combined and concentrated under reduced pressure to give a brown solid crude product. The crude product was purified by recrystallization from petroleum ether and analyzed by gas chromatography (GC) with a purity of 98%, and 227.1 g of the pure product was obtained after drying with a yield of 40.0%.

References

[1] Journal of the American Chemical Society, 2004, vol. 126, # 48, p. 15770 - 15776
[2] Patent: CN104530107, 2016, B. Location in patent: Paragraph 0026

4-Bromo-1-fluoro-2-nitrobenzene synthesis

1493-27-2
364-73-8
Synthesis of 4-Bromo-1-fluoro-2-nitrobenzene from 1-Fluoro-2-nitrobenzene

4-Bromo-1-fluoro-2-nitrobenzene Preparation Products And Raw materials

Raw materials

1-Fluoro-2-nitrobenzene 1-BROMO-4-FLUORO-2-NITROBENZENE 4-Bromofluorobenzene

Preparation Products

5-BROMO-2-FLUOROANILINE 2-Fluoroaniline 4-bromo-2,6-dinitrophenol 2,8-dibromooxanthrene 4-broMo-N1-Methylbenzene-1,2-diaMine
(4-BROMO-2-NITRO-PHENYL)-ACETIC ACID GNF 5837 Benzenamine, 4-bromo-N-(cyclopropylmethyl)-2-nitro- 4-BROMO-2-NITROPHENYLHYDRAZINE 2-((4-broMo-2-nitrophenyl)aMino)ethanol
4-broMo-2-nitrobenzene-1-sulfonyl chloride

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4-Bromo-1-fluoro-2-nitrobenzene Suppliers

Global( 342)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Dideu Medichem Co. Ltd 		+86-029-81138252 +86-173 9270 1263 1057@dideu.com China 4000 58
Hebei Chuanghai Biotechnology Co,.LTD 		+86-86-13131129325 +8613131129325 sales1@chuanghaibio.com China 5231 58
Frapp's ChemicalNFTZ Co., Ltd. 		+86 (576) 8169-6106 sales@frappschem.com China 880 50
Springchem New Material Technology Co.,Limited 		+86-021-62885108 +8613917661608 info@spring-chem.com China 2068 57
Capot Chemical Co.,Ltd. 		+8613336195806 sales@capot.com China 29640 60
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21588 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29815 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
Wuhan Chemwish Technology Co., Ltd 		027-67849912 sales@chemwish.com CHINA 10821 58
Supplier Advantage
Shaanxi Dideu Medichem Co. Ltd 		58
Hebei Chuanghai Biotechnology Co,.LTD 		58
Frapp's ChemicalNFTZ Co., Ltd. 		50
Springchem New Material Technology Co.,Limited 		57
Capot Chemical Co.,Ltd. 		60
Henan Tianfu Chemical Co.,Ltd. 		55
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
Alchem Pharmtech,Inc. 		58
Wuhan Chemwish Technology Co., Ltd 		58

View Lastest Price from 4-Bromo-1-fluoro-2-nitrobenzene manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Bromo-1-fluoro-2-nitrobenzene pictures 2026-05-28 4-Bromo-1-fluoro-2-nitrobenzene
364-73-8
 $10.00 1KG 95% 10 ton Hebei Chuanghai Biotechnology Co,.LTD
4-Bromo-1-fluoro-2-nitrobenzene pictures 2024-06-11 4-Bromo-1-fluoro-2-nitrobenzene
364-73-8
 $1.00 1kg 98% 20T Shaanxi Dideu Medichem Co. Ltd
4-Bromo-1-fluoro-2-nitrobenzene pictures 2022-02-21 4-Bromo-1-fluoro-2-nitrobenzene
364-73-8
 1KG 97.6% 100 tons Honest Joy Holdings Limited

4-Bromo-1-fluoro-2-nitrobenzene Spectrum

4-Bromo-1-fluoro-2-nitrobenzene(364-73-8)MS4-Bromo-1-fluoro-2-nitrobenzene(364-73-8)1HNMR4-Bromo-1-fluoro-2-nitrobenzene(364-73-8)IR1

364-73-8(4-Bromo-1-fluoro-2-nitrobenzene)Related Search:

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3-Bromo-2-fluoronitrobenzene 4-BROMO-2-FLUORO-6-NITROANISOLE 2-Bromo-1-fluoro-3-nitrobenzene 2-BROMO-1-FLUORO-4-NITROBENZENE,3-Bromo-4-fluoro-1-nitrobenzene 1-BROMO-4-FLUORO-2-NITROBENZENE
1-BROMO-3-FLUORO-4-NITROBENZENE Bromine 2-bromo-4-fluoro-1-nitrobenzene

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4-Bromo-1-fluoro-2-nitrobenzene,98% 4-BroMo-1-fluoro-2-nitrobenzene, 98% 5GR 4-Bromo-1-fluoro-2-n 5-Bromo-2-fL 5-BroMo-2-fluoronitrobenzene, 97+% 5 - broMine - 2 - fluoro nitrobenzene Benzene, 4-bromo-1-fluoro-2-nitro- 4-Bromo-1-fluoro-2-nitrobenzene 96% 4-BROMO-1-FLUORO-2-NITROBENZENE 2-fluoro-5-bromonitrobenzene 5-Bromo-2-fluoronitrobenzene 98% 5-Bromo-2-fluoronitrobenzene98% 1-BROMO-4-FLUORO-3-NITROBENZENE 4-Bromo-1-fluoro-2-nitrobenzene > 4-Bromo-2-nitrofluorobenzene 364-73-8 4-Bromo-1-fluoro-2-nitrobenzene 5-BROMO-2-FLUORONITROBENZENE 364-73-8 364-78-8 64-73-8 BrC6H3FNO2 Building Blocks Nitrogen Compounds Organic Building Blocks Nitro Compounds Aryl Fluorinated Building Blocks Building Blocks Chemical Synthesis Fluorinated Building Blocks Nitro Compounds Nitrogen Compounds Aromatic Halides (substituted) Miscellaneous Nitro Compounds Nitrogen Compounds Organic Building Blocks FluoroCompounds NitroCompounds Organic Building Blocks Organic Fluorinated Building Blocks Other Fluorinated Organic Building Blocks blocks Bromides C6