ChemicalBook >> CAS DataBase List >>HEPPSO
HEPPSO
- CAS No.
- 68399-78-0
- Chemical Name:
- HEPPSO
- Synonyms
- HEPPSO;beta-hy;HEPPSO 99+%;HEPPSO 98+%;HEPPSO Buffer;HEPPSO Hydrate;HEPPSO ULTRAPURE;HEPPSO, FREE ACID;HEPPSO Hydrate, >=99%;LABOTEST-BB LT00138033
- CBNumber:
- CB6739784
- Molecular Formula:
- C9H20N2O5S
- Molecular Weight:
- 268.33
- MDL Number:
- MFCD00038351
- MOL File:
- 68399-78-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-04-15 22:42:38
| Product description | Number | Pack Size | Price |
| 4-(2-Hydroxyethyl)piperazine-1-(2-hydroxypropane-3-sulfonic Acid) Hydrate [Good's buffer component for biological research] >98.0%(T) | H0772 | 25g | $88 |
| Heppso Hydrate | 280102 | 25g | $340 |
| HEPPSO, hydrate 99+% | 238902 | 5g | $170 |
| 4-(2-hydroxyerhyl)piperazine-1-(2-hydroxypropanesulfonicacid) | F991 | 100g | $262 |
| 2-Hydroxy-3-(4-(2-hydroxyethyl)piperazin-1-yl)propane-1-sulfonic acid 95+% | 094669 | 5g | $1040 |
| More product size | |||
| Melting point | 158-160°C |
|---|---|
| Density | 1.382±0.06 g/cm3(Predicted) |
| Water Solubility | almost transparency in Water |
| pka | 1.10±0.50(Predicted) |
| form | Liquid |
| color | White to Almost white |
| InChI | InChI=1S/C9H20N2O5S/c12-6-5-10-1-3-11(4-2-10)7-9(13)8-17(14,15)16/h9,12-13H,1-8H2,(H,14,15,16) |
| InChIKey | GIZQLVPDAOBAFN-UHFFFAOYSA-N |
| SMILES | N1(CCN(CCO)CC1)CC(O)CS(=O)(=O)O |
| CAS DataBase Reference | 68399-78-0(CAS DataBase Reference) |
| EPA Substance Registry System | 1-Piperazinepropanesulfonic acid, .beta.-hydroxy-4-(2-hydroxyethyl)- (68399-78-0) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301-H315-H319-H335 |
| Precautionary statements | P280-P301+P310-P362+P364 |
| Hazard Codes | T,Xi |
| Risk Statements | 25-36/37/38 |
| Safety Statements | 26-36-45-24/25 |
| WGK Germany | 3 |
| TSCA | TSCA listed |
| HS Code | 29335995 |
HEPPSO price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | H0772 | 4-(2-Hydroxyethyl)piperazine-1-(2-hydroxypropane-3-sulfonic Acid) Hydrate [Good's buffer component for biological research] >98.0%(T) | 68399-78-0 | 25g | $88 | 2026-03-19 | Buy |
| Usbiological | 280102 | Heppso Hydrate | 68399-78-0 | 25g | $340 | 2021-12-16 | Buy |
| Usbiological | 238902 | HEPPSO, hydrate 99+% | 68399-78-0 | 5g | $170 | 2021-12-16 | Buy |
| AK Scientific | F991 | 4-(2-hydroxyerhyl)piperazine-1-(2-hydroxypropanesulfonicacid) | 68399-78-0 | 100g | $262 | 2021-12-16 | Buy |
| Matrix Scientific | 094669 | 2-Hydroxy-3-(4-(2-hydroxyethyl)piperazin-1-yl)propane-1-sulfonic acid 95+% | 68399-78-0 | 5g | $1040 | 2021-12-16 | Buy |
HEPPSO Chemical Properties,Uses,Production
Chemical Properties
HEPPSO is a white solid.Solubility: H2O: 250 mg/mL (931.69 mM; Need ultrasonic); DMSO: 250 mg/mL (931.69 mM; Need ultrasonic)
Uses
HEPPSO is a zwitterionic buffer used in GMP-manufacturing of advanced therapy medication products.
Uses
HEPPSO shows no toxicity for crustaceans with which it has been studied and has been deemed suitable for toxicological studies. As an zwitterionic biological buffer, it often used in biological and biochemical research. It could used as an ampholytic separator to create a pH gradient in isoelectric focusing. HEPPSO is able to form radicals and is thus not suitable for redox reactions. It could forms a complex with Cu(II) ions so stability constants and concentrations should be taken into consideration when using this buffer in a solution containing copper ions. Although HEPPSO binds to coppers ions, it is still suitable for use as the bicinchoninic acid (BCA) assay. Diminished protein-induced color development can be accounted for or even eliminated through precipitating protein prior to reaction with bicinchoninic acid.
Definition
ChEBI: HEPPSO is a N-(2-hydroxyethyl)piperazine and a N-(sulfoalkyl)piperazine.
HEPPSO Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 283)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Suzhou Genemill Biotechnology Co.,Ltd | +8615862502491 | aimeegao@genemill.com | China | 39 | 58 |
| Hubei Xindesheng Material Technology Co., Ltd. | +8618971041571 | vickyzhao@whdschem.com | China | 174 | 58 |
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 | niki@zlchemi.com | China | 7245 | 58 |
| Wuhan Hugarise New Material Co.,Ltd | +86-15391547019 +86-13296613823 | info@hugarise.com | China | 242 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29821 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 +8613506123987 | marketing1@neostarunited.com | China | 8828 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 9546 | 58 |
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 8796 | 58 |
View Lastest Price from HEPPSO manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-21 | β-hydroxy-4-(2-hydroxyethyl)piperazine-1-propanesulphonic acid (HEPPSO)
68399-78-0
|
US $0.00 / kg | 25kg | ≥99 % | 300tons/year | Wuhan Hugarise New Material Co.,Ltd | |
 |
2025-05-23 | HEPPSO
68399-78-0
|
US $79.00-38.00 / kg | 1kg | 99% | 20ton | Hebei Zhuanglai Chemical Trading Co Ltd | |
 |
2024-07-12 | HEPPSO
68399-78-0
|
US $0.00 / kg | 1kg | 99.5% | 1000tons | Suzhou Genemill Biotechnology Co.,Ltd |
-
- β-hydroxy-4-(2-hydroxyethyl)piperazine-1-propanesulphonic acid (HEPPSO)
68399-78-0
- US $0.00 / kg
- ≥99 %
- Wuhan Hugarise New Material Co.,Ltd
-
- HEPPSO
68399-78-0
- US $79.00-38.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co Ltd
-
- HEPPSO
68399-78-0
- US $0.00 / kg
- 99.5%
- Suzhou Genemill Biotechnology Co.,Ltd
HEPPSO Spectrum
N-(Hydroxyethyl)piperazine-N'-2-hydroxypropanesulfonic acid(68399-78-0)1HNMRN-(Hydroxyethyl)piperazine-N'-2-hydroxypropanesulfonic acid(68399-78-0)13CNMRN-(Hydroxyethyl)piperazine-N'-2-hydroxypropanesulfonic acid(68399-78-0)IR1N-(Hydroxyethyl)piperazine-N'-2-hydroxypropanesulfonic acid(68399-78-0)IR2
4-(2-hydroxyethyl)piperazine-1-(2-hydr.prop.sulf.ac.)1h2o
beta-hydroxy-4-(2-hydroxyethyl)-1-piperazinepropanesulfonicaci
β-Hydroxy-4-(2-hydroxyethyl)-1-piperazinepropanesulfonic acid monohydrate, N-(2-Hydroxyethyl)piperazine-Nμ-(2-hydroxypropanesulfonic acid), 4-(2-Hydroxyethyl)piperazine-1-(2-hydroxypropanesulfonic acid) monohydrate
4-(2-Hydroxyethyl)piperazine-1-(2-hydroxypropanesulfonic acid) Hydrate hydrate
HEPPSO Hydrate
2-Hydroxy-3-(4-(2-hydroxyethyl)-1-piperazinyl)propane-1-sulfonic acid
2-Hydroxy-3-[4-(2-hydroxyethyl)-1-piperazinyl]propane-1-sulfonic acid
2-Hydroxy-3-[4-(2-hydroxyethyl)piperazino]-1-propanesulfonic acid
3-[4-(2-Hydroxyethyl)-1-piperazinyl]-2-hydroxypropane-1-sulfonic acid
4-(2-Hydroxyethyl)-β-hydroxy-1-piperazinepropane-1-sulfonic acid
HEPPSO (4-(2-Hydroxyethyl)piperazine-1-(2-hydroxypropanesulfonic
2-hydroxy-3-[4-(2-hydroxyethyl)piperazin-1-yl]propane-1-sulfonic acid
1-Piperazinepropanesulfonic acid
beta-hy
HEPPSO
3-[4-(2-Hydroxyethyl)-1-piperazinyl]-2-hydroxypropanesulfonic Acid
4-(2-Hydroxyethyl)piperazine-1-(2-hydroxypropane-3-sulfonic Acid)
4-(2-Hydroxyethyl)piperazine-1-(2-hydroxypropane-3-sulfonic Acid) Hydrate
HEPPSO) 4-(2-Hydroxyethyl)piperazine-1-(2-hydroxypropanesulfoni
HEPPSO (N-[2-Hydroxyethyl]Piperazine-N'-[2-HYDROXYPROPANESULFONIC ACID]),Free Acid
4-(2-Hydroxyethyl)piperazine-1-(2-hydroxypropanesulfonic acid) Monohydrate (HEPPSO)
HEPPSO Hydrate, >=99%
N-(2-HYDROXYETHYL)PIPERAZINE-N'-2-HYDROXY PROPANESULPHONIC ACID
N-[2-HYDROXYETHYL]PIPERAZINE-N'-[2-HYDROXYPROPANESULFONIC ACID
4-(2-HYDROXYETHYL)PIPERAZINE-1-(2-HYDROXYPROPANE-3-SULFONIC ACID)
4-(2-HYDROXYETHYL)PIPERAZINE-1-(2-HYDROXYPROPANESULFONIC ACID)
N-(Hydroxyethyl)piperazine-N'-2-hydroxypropanesulfonic acid
β-Hydroxy-4-(2-hydroxyethyl)-1-piperazinepropanesulfonic acid monohydrate
HEPPSO N-(2-Hydroxyethyl)piperazine-N-2-hydroxypropanesulfonic acid
beta-hydroxy-4-(2-hydroxyethyl)piperazine-1-propanesulphonic acid
4-(2-HYDROXYETHYL)PIPERAZINE-1-(2-HYDR.&
HEPPSO 99+%
HEPPSO 98+%
-(2-HYDROXYETHYL)PIPERAZINE-1-2-HYDROXYPROPANESULFONIC ACID
4-(2-HYDROXYERHYL)PIPERAZINE-1-(2-HYDROXY PROPANESULFONIC ACID)
N-(2-Hydroxyethyl)piperazine-N’-2-hydroxypropanesulfonic acidHEPPSO
HEPPSO (4-(2-HYDROXYETHYL)PIPERAZINE-1-(2-HYDROXYPROPANESULFONIC ACID))
HEPPSO ULTRAPURE
N-(2-Hydroxyethyl)piperazine-N'-2-hydroxypropanesulphonic acid >98%
LABOTEST-BB LT00138033
1-Piperazinepropanesulfonic acid, beta-hydroxy-4-(2-hydroxyethyl)-
4-(2-Hydroxyethyl)piperazine-1-(2-hydroxypropanesulfonic acid) monohydrate
3-[4-(2-HYDROXYETHYL)-1-PIPERAZINYL]-2-HYDROXYPROPANESULFONIC ACID
HEPPSO
2-Hydroxy-3-[4-(2-hydroxyethyl)-1-piperazinyl]propanesulfonicacid,monohydrate
HEPPSO, FREE ACID
HEPPSO N-(Hydroxyethyl)piperazine-N'-2-hydroxypropanesulfonic acid
3-[4-(2-Hydroxyethyl)-1-piperazinyl]-2-hydroxypropanesulfonic Acid Hydrate
1-Piperazinepropanesulfonic acid, β-hydroxy-4-(2-hydroxyethyl)-
N-(Hydroxyethyl)piperazine-N'-2-hydroxypropanesulfonic
3- (hydroxyethyl piperazine) -2-hydroxypropanesulfonic acid(HEPPSO)
3-(Hydroxyethylpiperazine)-2-hydroxypropanesulfonic acid
4-(2-Hydroxyethyl)piperazine-1-(2-hydroxypropane-3-sulfonic Acid) Hydrate [Good's buffer coMponent for biological research]
4-(2-Hydroxyethyl)piperazine-1-(2-hydroxypropane-3-sulfonic Acid) [Good's buffer component for biological research]
HEPPSO Buffer
4-(2-Hydroxyethyl)piperazine-1-(2-hydroxypropane-3-sulfonicAcid)Hydrate[Good'sbuffercomponentforbiologicalresearch]>
N-(Hydroxyethyl)piperazine-N'-2-hydroxypropanesulfonic acid
HEPPSO Buffer 0.2M, pH 8.0
HEPPSO Buffer 0.2M, pH 7.5
