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6-BROMO-1H-INDAZOL-3-YLAMINE

CAS No.
404827-77-6
Chemical Name:
6-BROMO-1H-INDAZOL-3-YLAMINE
Synonyms
AURORA KA-4388;3-AMino-6-BroMoindazole;6-BROMO-1H-INDAZOL-3-AMINE;1H-Indazol-3-amine,6-bromo-;3-Amino-6-bromo-1H-indazole;6-BROMO-1H-INDAZOLE-3-AMINE;6-BROMO-1H-INDAZOL-3-YLAMINE;6-Bromo-2h-indazol-3-ylamine;6-Bromo-1H-indazol-3-amine 95%;3-Amino-6-bromo-1H-indazole 95%
CBNumber:
CB6754457
Molecular Formula:
C7H6BrN3
Molecular Weight:
212.05
MDL Number:
MFCD05665872
MOL File:
404827-77-6.mol
Last updated:2025-09-25 17:15:13
Product description Number Pack Size Price
6-Bromo-1H-indazol-3-amine B686228 10mg $45
3-Amino-6-bromo-1H-indazole 95% 3H30-9-X9 1g $29
3-Amino-6-bromo-1H-indazole 95% OR9913 1g $18
6-Bromo-1H-indazol-3-yl-amine FB50866 500mg $65
3-Amino-6-bromo-1H-indazole 95% 3H30-9-X9 5G $87
More product size

6-BROMO-1H-INDAZOL-3-YLAMINE Properties

Melting point 237-240
Boiling point 431.3±25.0 °C(Predicted)
Density 1.867±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
form Crystalline Powder
pka 13.68±0.40(Predicted)
color White to off-white
InChI InChI=1S/C7H6BrN3/c8-4-1-2-5-6(3-4)10-11-7(5)9/h1-3H,(H3,9,10,11)
InChIKey WLDHNAMVDBASAW-UHFFFAOYSA-N
SMILES N1C2=C(C=CC(Br)=C2)C(N)=N1

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi,Xn
Risk Statements  22
RIDADR  UN2811
HazardClass  IRRITANT
HS Code  29339980
Limited Quantities 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)

6-BROMO-1H-INDAZOL-3-YLAMINE price More Price(43)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC B686228 6-Bromo-1H-indazol-3-amine 404827-77-6 10mg $45 2021-12-16 Buy
SynQuest Laboratories 3H30-9-X9 3-Amino-6-bromo-1H-indazole 95% 404827-77-6 1g $29 2021-12-16 Buy
Apolloscientific OR9913 3-Amino-6-bromo-1H-indazole 95% 404827-77-6 1g $18 2021-12-16 Buy
Biosynth Carbosynth FB50866 6-Bromo-1H-indazol-3-yl-amine 404827-77-6 500mg $65 2021-12-16 Buy
SynQuest Laboratories 3H30-9-X9 3-Amino-6-bromo-1H-indazole 95% 404827-77-6 5G $87 2021-12-16 Buy
Product number Packaging Price Buy
B686228 10mg $45 Buy
3H30-9-X9 1g $29 Buy
OR9913 1g $18 Buy
FB50866 500mg $65 Buy
3H30-9-X9 5G $87 Buy

6-BROMO-1H-INDAZOL-3-YLAMINE Chemical Properties,Uses,Production

Synthesis

4-Bromo-2-fluorobenzonitrile

105942-08-3

6-BROMO-1H-INDAZOL-3-YLAMINE

404827-77-6

Under nitrogen protection, 4-bromo-2-fluorobenzonitrile (5 g, 25.13 mmol) was dissolved in 20 mL of n-butanol, followed by hydrazine hydrate (1.04 mL, 50.26 mmol). The reaction mixture was heated to reflux and kept for 4 hours. Upon completion of the reaction, it was cooled to room temperature and a large amount of solid was observed to precipitate. The solid product was collected by diafiltration and the filter cake was washed with petroleum ether to remove impurities. Finally, the resulting white solid was dried to give 4.759 g of the target product 6-bromo-1H-indazol-3-amine in 85.7% yield.

References

[1] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 14, p. 4579 - 4584
[2] Bioorganic and Medicinal Chemistry Letters, 2010, vol. 20, # 6, p. 1985 - 1989
[3] Patent: CN106032359, 2016, A. Location in patent: Paragraph 0044; 0045; 0046
[4] Bioorganic and Medicinal Chemistry, 2018, vol. 26, # 3, p. 747 - 757
[5] Patent: CN106146493, 2016, A. Location in patent: Paragraph 0452; 0453; 0454; 0455

105942-08-3
404827-77-6
Synthesis of 6-BROMO-1H-INDAZOL-3-YLAMINE from 4-Bromo-2-fluorobenzonitrile

6-BROMO-1H-INDAZOL-3-YLAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 6-BROMO-1H-INDAZOL-3-YLAMINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
6-BROMO-1H-INDAZOL-3-YLAMINE pictures 2020-01-09 6-BROMO-1H-INDAZOL-3-YLAMINE
404827-77-6
US $3.00 / KG 1KG 98% 200KG Career Henan Chemical Co

6-BROMO-1H-INDAZOL-3-YLAMINE Spectrum

AURORA KA-4388 6-BROMO-1H-INDAZOL-3-AMINE 6-BROMO-1H-INDAZOL-3-YLAMINE 6-BROMO-1H-INDAZOLE-3-AMINE 3-Amino-6-bromo-1H-indazole 6-Bromo-1H-indazol-3-amine 95% 3-Amino-6-bromo-1H-indazole 95% 3-AMino-6-BroMoindazole 3-Amino-6-bromo-1H-indazole 1H-Indazol-3-amine,6-bromo- ethyl 3-(3-(cyclopropanecarboxamido)-1H-indazol-6-yl)benzoate 6-Bromo-2h-indazol-3-ylamine 6-BROMO-1H-INDAZOL-3-YLAMINE 404827-77-6 3-Pyridinecarboxaldehyde,2,8-dichloro- 2-Propenoicacid,7-bromoethylester 404827-77-6 Amines CHIRAL CHEMICALS Fused Ring Systems Building Blocks Indazole