4-Chloro-3-nitroquinoline
- CAS No.
- 39061-97-7
- Chemical Name:
- 4-Chloro-3-nitroquinoline
- Synonyms
- 3-Nitro-4-chloroquinoline;4-CHLORO-3-NITROQUINOLINE;4-Chloro-3-nitroqulinoline;QUINOLINE, 4-CHLORO-3-NITRO-;4-Chloro-3-nitroquinoline ,98%;4-Chloro-3-nitroquinoline ISO 9001：2015 REACH
- CBNumber:
- CB6760548
- Molecular Formula:
- C9H5ClN2O2
- Molecular Weight:
- 208.6
- MDL Number:
- MFCD07369246
- MOL File:
- 39061-97-7.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 4-Chloro-3-nitroquinoline | C374825 | 25g | $590 |
| 4-Chloro-3-nitroquinoline | FC20069 | 50g | $600 |
| 4-Chloro-3-nitroquinoline 95+% | 072162 | 25g | $628 |
| 4-CHLORO-3-NITROQUINOLINE 95.00% | HCH0023468 | 1G | $704.55 |
| 4-Chloro-3-nitroquinoline 98% | JK221037 | 1g | $199 |
| More product size | |||
| Melting point | 121-122°C |
|---|---|
| Boiling point | 333.8±22.0 °C(Predicted) |
| Density | 1.484±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | -0.28±0.24(Predicted) |
| color | Pale Yellow |
| InChI | InChI=1S/C9H5ClN2O2/c10-9-6-3-1-2-4-7(6)11-5-8(9)12(13)14/h1-5H |
| InChIKey | ZRFUZDDJSQVQBY-UHFFFAOYSA-N |
| SMILES | N1C2C(=CC=CC=2)C(Cl)=C([N+]([O-])=O)C=1 |
| CAS DataBase Reference | 39061-97-7(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| Safety Statements | 24/25 |
| HS Code | 29334900 |
4-Chloro-3-nitroquinoline price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | C374825 | 4-Chloro-3-nitroquinoline | 39061-97-7 | 25g | $590 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC20069 | 4-Chloro-3-nitroquinoline | 39061-97-7 | 50g | $600 | 2021-12-16 | Buy |
| Matrix Scientific | 072162 | 4-Chloro-3-nitroquinoline 95+% | 39061-97-7 | 25g | $628 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0023468 | 4-CHLORO-3-NITROQUINOLINE 95.00% | 39061-97-7 | 1G | $704.55 | 2021-12-16 | Buy |
| Frontier Specialty Chemicals | JK221037 | 4-Chloro-3-nitroquinoline 98% | 39061-97-7 | 1g | $199 | 2021-12-16 | Buy |
4-Chloro-3-nitroquinoline Chemical Properties,Uses,Production
Chemical Properties
yellow crystal powder
Uses
4-Chloro-3-nitroquinoline (cas# 39061-97-7) is a compound useful in organic synthesis.
Synthesis
50332-66-6
39061-97-7
General procedure for the synthesis of 4-chloro-3-nitroquinoline from 4-hydroxy-3-nitroquinoline: The intermediate 3-nitro-4-hydroxyquinoline (18.7 g, 98.4 mmol) was suspended in dichloromethane (150 mL). Thionyl chloride (17.2 mL, 236 mmol) and N,N-dimethylformamide (DMF, 9.2 mL, 118 mmol) were added sequentially to the suspension. The reaction mixture was heated to reflux and kept reacting overnight. Upon completion of the reaction, the mixture was slowly poured into ice water. The organic and aqueous layers were separated and the organic layer was washed sequentially with saturated sodium bicarbonate solution, water and saturated brine. The organic layer was dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The resulting residue (20.52 g, 93% yield) can be used directly in the subsequent reaction without further purification.
References
[1] Patent: EP2674170, 2013, A1. Location in patent: Paragraph 0228
[2] Patent: US2014/141033, 2014, A1. Location in patent: Page/Page column
[3] Journal of Medicinal Chemistry, 1991, vol. 34, # 3, p. 1202 - 1206
[4] Journal of Medicinal Chemistry, 2006, vol. 49, # 11, p. 3354 - 3361
[5] Patent: WO2007/89507, 2007, A1. Location in patent: Page/Page column 20-21
4-Chloro-3-nitroquinoline Preparation Products And Raw materials
Raw materials
1of3
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | stella@zetchem.com | China | 2994 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10404 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29795 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14304 | 58 |
| Hebei Zhanyao Biotechnology Co. Ltd | 15369953316 +8615369953316 | admin@zhanyaobio.com | China | 2123 | 58 |
| Unipharm pharmaceutical industry Co., Ltd | 536-8266195 +8613953676784 | lee@unipharm-sd.com | China | 1202 | 58 |
View Lastest Price from 4-Chloro-3-nitroquinoline manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-20 | 4-Chloro-3-nitroquinoline
39061-97-7
|
US $0.00-0.00 / mg | 10g | TargetMol Chemicals Inc. | |||
 |
2025-11-18 | 4-Chloro-3-nitroquinoline
39061-97-7
|
US $1.10 / g | 1g | 99.00% | 100 Tons | Dideu Industries Group Limited | |
 |
2021-10-15 | 4-Chloro-3-nitroquinoline
39061-97-7
|
US $10.00 / KG | 1KG | 99% | 20 tons | Hebei Zhanyao Biotechnology Co. Ltd |
-
- 4-Chloro-3-nitroquinoline
39061-97-7
- US $0.00-0.00 / mg
- TargetMol Chemicals Inc.
-
- 4-Chloro-3-nitroquinoline
39061-97-7
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
-
- 4-Chloro-3-nitroquinoline
39061-97-7
- US $10.00 / KG
- 99%
- Hebei Zhanyao Biotechnology Co. Ltd
