ChemicalBook >> CAS DataBase List >>3-Amino-5-fluoropyridine

3-Amino-5-fluoropyridine

3-Amino-5-fluoropyridine structure

CAS No.: 210169-05-4

Chemical Name:: 3-Amino-5-fluoropyridine

Synonyms: 5-Fluoropyridin-3-amine;5-Fluoro-3-pyridinamine;3-AMINO-5-FLUOROPYRIDINE;3-PyridinaMine,5-fluoro-;3-Amine-5-fluoro-pyridin;5-Fluoropyridin-3-ylamine;3-AMine-5-fluoro-pyridine;3-Amino-5-fluoropyridine >3-aMino -5-fluorine pyridine;3-AMINO-5-FLUOROPYRIDINE 97%

CBNumber:: CB6767921

Molecular Formula:: C5H5FN2

Molecular Weight:: 112.11

MDL Number:: MFCD00234073

MOL File:: 210169-05-4.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 04:19:40

Product description	Number	Pack Size	Price
3-Amino-5-fluoropyridine	732176	500mg	$131
3-Amino-5-fluoropyridine >97.0%(GC)(T)	A2753	1g	$41
3-Amino-5-fluoropyridine >97.0%(GC)(T)	A2753	5g	$143
3-Amino-5-fluoropyridine	FA104369	25g	$194.75
3-Amino-5-fluoropyridine	FA104369	50g	$324.5
More product size

Request For Quotation

3-Amino-5-fluoropyridine Properties

Melting point	86°C
Boiling point	232.7±20.0 °C(Predicted)
Density	1.257±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
form	powder to crystal
pka	3.74±0.20(Predicted)
color	Light orange to Yellow to Green
InChI	InChI=1S/C5H5FN2/c6-4-1-5(7)3-8-2-4/h1-3H,7H2
InChIKey	ZRORIJXOWXYPMO-UHFFFAOYSA-N
SMILES	C1=NC=C(F)C=C1N
CAS DataBase Reference	210169-05-4(CAS DataBase Reference)
FDA UNII	T287Q2D5WG
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P264-P270-P301+P312-P302+P352-P305+P351+P338

target organs

Respiratory system

Hazard Codes

Xi,Xn

Risk Statements

20/21/22-36/37/38-22

Safety Statements

26-36-36/37

WGK Germany

HazardClass

IRRITANT

HS Code

2933399990

Storage Class

11 - Combustible Solids

Hazard Classifications

Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

NFPA 704

	0
2		0

3-Amino-5-fluoropyridine price More Price(87)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	732176	3-Amino-5-fluoropyridine	210169-05-4	500mg	$131	2023-06-20	Buy
TCI Chemical	A2753	3-Amino-5-fluoropyridine >97.0%(GC)(T)	210169-05-4	1g	$41	2026-04-30	Buy
TCI Chemical	A2753	3-Amino-5-fluoropyridine >97.0%(GC)(T)	210169-05-4	5g	$143	2026-04-30	Buy
Biosynth	FA104369	3-Amino-5-fluoropyridine	210169-05-4	25g	$194.75	2026-06-04	Buy
Biosynth	FA104369	3-Amino-5-fluoropyridine	210169-05-4	50g	$324.5	2026-06-04	Buy

Product number	Packaging	Price	Buy
732176	500mg	$131	Buy
A2753	1g	$41	Buy
A2753	5g	$143	Buy
FA104369	25g	$194.75	Buy
FA104369	50g	$324.5	Buy

3-Amino-5-fluoropyridine Chemical Properties,Uses,Production

Chemical Properties

Light yellow Crystal

Uses

3-amino-5-fluoropyridine is an important intermediate mainly used in medicine and organic synthesis. It is used to synthesize Ivosidenib. Ivosidenib is an isocitrate dehydrogenase-1 inhibitor used to treat acute myeloid leukemia and cholangiocarcinoma in adults.

Application

Reactant for:
Preparation of nonpeptide inhibitors of measles virus entry.

Preparation

synthesis of 3-Amino-5-fluoropyridine: A solution of 3-amino-2,4,6-tribromo-5-fluoropyridine (23c) (0.9 g, 2.6 mmol), triethylamine (1.1 cm3, 7.9 mmol), palladium catalyst (0.1 g of 5% Pd-C catalyst) and DCM (15 cm3) was hydrogenated on a Parr apparatus for 18 h. Water (20 cm3) was added and the mixture filtered and extracted into DCM. The DCM solution was dried (MgS04) and evaporated giving 3-amino-5-fluoropyridine (0.3 g, >95% ), m.p. 86 ·c (from DCM) (Found: C, 53.6; H, 4.6; N, 25.0. C5H5FN2 requires C, 53.6; H, 4.5 N, 25.0%);
IR spectrum no. 9; mass spectrum no. 5; nmr spectrum no. 29.

3-Amino-5-fluoropyridine synthesis

Synthesis of 3-Amino-5-fluoropyridine from 5-Fluoronicotinamide

3-Amino-5-fluoropyridine Preparation Products And Raw materials

Raw materials

4-Methylmorpholine Hexane Isoamyl nitrite Ethanol Ammonium formate

Diphenylphosphoryl azide Benzyl alcohol 5-Fluoronicotinic acid Palladium Fluoroboric acid

Diethyl ether 1,2-Dichloroethane 5-Methylpyridin-3-amine Hydrochloric acid Methanol

Carbamic acid, N-(5-fluoro-3-pyridinyl)-, phenylmethyl ester 2,6-DICHLORO-5-FLUORONICOTINOYL CHLORIDE 2,4,6-TRIBROMO-3,5-DIFLUOROPYRIDINE

1of4

Preparation Products

3-Amino-5-fluoropyridine Suppliers

Global( 343)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	13901	58
Hi-Tech Chemistry Corp	0519-86626038	yuhh@hitechem.com	CHINA	810	58
Dongfan Chem. Co., Ltd.	021-34500607 13391355195	sales@dfanchem.com	CHINA	61	55
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21587	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29815	58
Changzhou Ansciep Chemical Co., Ltd.	+86 519 86305871	sales@ansciepchem.com	CHINA	4241	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10403	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Hi-Tech Chemistry Corp	58
Dongfan Chem. Co., Ltd.	55
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Changzhou Ansciep Chemical Co., Ltd.	58
Shenzhen Nexconn Pharmatechs Ltd	58
Jinan Carbotang Biotech Co.,Ltd.	58

View Lastest Price from 3-Amino-5-fluoropyridine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-12-29	3-Amino-5-fluoropyridine 210169-05-4		1kg	99%		Changzhou waston chemical technology Co.,Ltd
2025-06-25	3-AMINO-5-FLUOROPYRIDINE 210169-05-4	$1.10	1g	99.0% min	100 tons min	Shaanxi Dideu Medichem Co. Ltd
2022-02-19	5-fluoropyridin-3-amine 210169-05-4		1KG	98.7%	100 tons	Honest Joy Holdings Limited

3-Amino-5-fluoropyridine
210169-05-4
$0.00
99%
Changzhou waston chemical technology Co.,Ltd

3-AMINO-5-FLUOROPYRIDINE
210169-05-4
$1.10
99.0% min
Shaanxi Dideu Medichem Co. Ltd

5-fluoropyridin-3-amine
210169-05-4
$0.00
98.7%
Honest Joy Holdings Limited

3-Amino-5-fluoropyridine Spectrum

3-Amino-5-fluoropyridine(210169-05-4)¹HNMR 3-Amino-5-fluoropyridine(210169-05-4)FT-IR

210169-05-4(3-Amino-5-fluoropyridine)Related Search:

5-Fluoro-2-oxindole 4-BROMO-5-FLUORO-2-HYDROXY-3-NITROPYRIDINE 2-BROMO-5-FLUORO-3-NITROPYRIDINE 2-AMINO-3-NITRO-5-FLUOROPYRIDINE 3-FLUORO-4-NITROPYRIDINE-N-OXIDE

2-CHLORO-5-FLUORO-3-NITROPYRIDINE 3-Fluoro-4-nitropyridine 4-AMINO-2,3,5,6-TETRAFLUOROPYRIDINE 3-Amino-5-fluoropyridine 2-CHLORO-3-FLUORO-4-NITROPYRIDINE N-OXIDE

4-(DIMETHYLAMINO)-2,3,5,6-TETRAFLUOROPYRIDINE 5-FLUORO-2-HYDROXY-3-NITROPYRIDINE 4-AMINO-3-CHLORO-2,5,6-TRIFLUOROPYRIDINE 4-Amino-2-fluoropyridine97%,4-AMINO-2-FLUOROPYRIDINE 2-Amino-5-fluoropyridine

6-FLUORO-3,4-PYRIDINEDIAMINE 2-Amino-3-fluoropyridine97%,2-AMINO-3-FLUOROPYRIDINE 98%,2-AMINO-3-FLUOROPYRIDINE BOC-5-AMINO-2-FLUOROPYRIDINE,N-Boc-5-amino-2-fluoropyridine

1of4

3-AMINO-5-FLUOROPYRIDINE 3-Pyridinamine,5-fluoro-(9CI) 3-AMINO-5-FLUOROPYRIDINE 97% 5-Fluoropyridin-3-ylamine 3-Amine-5-fluoro-pyridin 3-AMine-5-fluoro-pyridine 3-PyridinaMine,5-fluoro- 3-aMino -5-fluorine pyridine 5-Fluoro-3-pyridinamine 3-AMINO-5-FLUOROPYRIDINE(RS20014327) 3-Amino-5-fluoropyridine > 3-AMINO-5-FLUOROPYRIDINE ISO 9001：2015 REACH 210169-05-4 5-Fluoropyridin-3-amine 210169-05-4 Fluorine series Building Blocks C5 C5 to C6 Chemical Synthesis Fluorinated Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks Heterocyclic Fluorinated Building Blocks Other Fluorinated Heterocycles Pyridine series Pyridines Boronic Acid PYRIDINE AMINEPRIMARY HALIDE