(RS)-MCPG
- CAS No.
- 146669-29-6
- Chemical Name:
- (RS)-MCPG
- Synonyms
- (RS)-MCPG;(+/-)MCPG;[+/-]-MCPG;alpha-MCPG;(RS)-MCPG, 10 mM in DMSO;alpha-Amino-4-Carboxy-alpha;(RS)-α-Methyl-4-carboxyphenylglycine;(RS)-A-METHYL-4-CARBOXYPHENYLGLYCINE;(RS)-α-Methyl-4- carboxyphenylglycine;(±)-α-Methyl-(4-carboxyphenyl)glycine
- CBNumber:
- CB6778633
- Molecular Formula:
- C10H11NO4
- Molecular Weight:
- 209.2
- MDL Number:
- MFCD00210205
- MOL File:
- 146669-29-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| (±)-α-Methyl-(4-carboxyphenyl)glycine | M4796 | 25mg | $546 |
| (±)-α-Methyl-(4-carboxyphenyl)glycine | M4796 | 5mg | $190 |
| (RS)-MCPG | 464860 | 5mg | $396 |
| (RS)-MCPG | 464860 | 10mg | $559 |
| (RS)-MCPG Asreported | 256527 | 10mg | $403 |
| Boiling point | 425.3±40.0 °C(Predicted) |
|---|---|
| Density | 1.390±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | DMSO : 6 mg/mL (28.68 mM; Need ultrasonic and warming) |
| form | Powder |
| pka | 1.76±0.10(Predicted) |
| color | White |
| InChI | 1S/C10H11NO4/c1-10(11,9(14)15)7-4-2-6(3-5-7)8(12)13/h2-5H,11H2,1H3,(H,12,13)(H,14,15) |
| InChIKey | DNCAZYRLRMTVSF-UHFFFAOYSA-N |
| SMILES | CC(N)(C(O)=O)c1ccc(cc1)C(O)=O |
| CAS DataBase Reference | 146669-29-6(CAS DataBase Reference) |
| FDA UNII | 7HJ67IIE31 |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
| PPE | Eyeshields, Gloves, type N95 (US) |
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
(RS)-MCPG price More Price(59)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | M4796 | (±)-α-Methyl-(4-carboxyphenyl)glycine | 146669-29-6 | 25mg | $546 | 2024-03-01 | Buy |
| Sigma-Aldrich | M4796 | (±)-α-Methyl-(4-carboxyphenyl)glycine | 146669-29-6 | 5mg | $190 | 2023-06-20 | Buy |
| Usbiological | 464860 | (RS)-MCPG | 146669-29-6 | 5mg | $396 | 2026-06-03 | Buy |
| Usbiological | 464860 | (RS)-MCPG | 146669-29-6 | 10mg | $559 | 2026-06-03 | Buy |
| Usbiological | 256527 | (RS)-MCPG Asreported | 146669-29-6 | 10mg | $403 | 2026-06-03 | Buy |
(RS)-MCPG Chemical Properties,Uses,Production
Uses
(RS)-MCPG is a non-selective group I/group II metabotropic glutamate receptor antagonist.
Biological Activity
Non-selective group I/group II metabotropic glutamate receptor antagonist. See (S)-isomer ((S)-a-Methyl-4-carboxyphenylglycine ).
in vivo
(RS)-MCPG (alpha-MCPG; 500 μM) blocks the TBS-induced shifts in EGABA in either juvenile or neonatal neurons[1].
Pretreatment with the low dose of (RS)-MCPG (25 nM; i.c.; daily; 5 days) significantly attenuates amphetamine-induced locomotor activity in 10-day-old male and female rats of Sprague-Dawley descent[2].
IC 50
mGluR
storage
Room temperature
(RS)-MCPG Preparation Products And Raw materials
Raw materials
Preparation Products
(RS)-MCPG Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19853 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39039 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Mainchem Co., Ltd. | +86-0592-6210733 | sale@mainchem.com | China | 32343 | 55 |
| J & K SCIENTIFIC LTD. | 18210857532; 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15838 | 69 |
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 6002 | 61 |
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