ChemicalBook >> CAS DataBase List >>Futuximab
Futuximab
- CAS No.
- 1310460-85-5
- Chemical Name:
- Futuximab
- Synonyms
- Futuximab
- CBNumber:
- CB68080859
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Last updated:2025-04-18 09:52:32
| form | Liquid |
|---|---|
| color | Colorless to light yellow |
| FDA UNII | B37J680LX0 |
| NCI Drug Dictionary | futuximab |
Futuximab Chemical Properties,Uses,Production
Uses
Futuximab is a chimeric monoclonal antibody targeting non-overlapping epitopes on EGFR. Futuximab has antineoplastic activity[1].
in vivo
Futuximab (50 mg/kg; i.p.; twice weekly; for 5 weeks) shows anti-tumor activity in EGFRwt expressing xenograft model[1].
| Animal Model: | Balb/c nu/nu mice injected with EGFRwt (D08-0308MG) patient-derived glioblastoma xenografts (PDX)[1] |
| Dosage: | 50 mg/kg |
| Administration: | i.p.; twice weekly; for 5 weeks |
| Result: | Inhibited tumor growth in EGFRwt expressing xenograft model. |
References
[1] Stephen T Keir, et al. Sym004-induced EGFR elimination is associated with profound anti-tumor activity in EGFRvIII patient-derived glioblastoma models. J Neurooncol. 2018 Jul;138(3):489-498. DOI:10.1007/s11060-018-2832-6
Futuximab Preparation Products And Raw materials
Raw materials
Preparation Products
Futuximab Suppliers
Global( 9)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
| Guangzhou Hongyuan Chemical Co.,Ltd | 15817493340 | 981810490@qq.com | China | 1566 | 58 |
| Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 | 422450190@qq.com | China | 10308 | 58 |
| Wuhan Jingkangen Biomedical Technology Co., Ltd | 13720134139 086-15871494362 13720134139 | orders@jknbiochem.com | China | 6262 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11973 | 58 |
| Changsha Fuzhen Biotechnology Co.，LTD | 0731-13823398 15111215862 | 313359644@qq.com | China | 3805 | 58 |
| Olix (Shanghai) Pharmaceutical Technology Co., Ltd | 17316404525 17316404525 | 209533805@qq.com | China | 9979 | 58 |
| Wanxin Biotechnology (Jiaxing) Co., LTD | 0573-83568680 18057391398 | 3956524501@qq.com | China | 1442 | 58 |
| Biosynth Biological Technology (Suzhou) Co Ltd | 51288865780 | sales@biosynth.com | China | 6051 | 58 |
Futuximab
1310460-85-5
