Domagrozumab
- CAS No.
- 1629605-31-7
- Chemical Name:
- Domagrozumab
- Synonyms
- Domagrozumab;Domagrozumab (anti-GDF8);Research Grade Domagrozumab;Research Grade Domagrozumab(DHA30603)
- CBNumber:
- CB68080985
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
- MSDS File:
- SDS
- TDS File:
- TDS
| form | Liquid |
|---|---|
| color | Colorless to light yellow |
| FDA UNII | 516MD5WQ24 |
Domagrozumab price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0635038 | Domagrozumab 96.34% | 1629605-31-7 | 1mg | $433 | 2026-06-04 | Buy |
| ChemScene | CS-0635038 | Domagrozumab 96.34% | 1629605-31-7 | 5mg | $1300 | 2026-06-04 | Buy |
| ChemScene | CS-0635038 | Domagrozumab 96.34% | 1629605-31-7 | 10mg | $2058 | 2026-06-04 | Buy |
| aablocks | AA02DJM6 | Domagrozumab ≥95%(SDS-PAGE&SEC-HPLC) | 1629605-31-7 | 1mg | $664 | 2026-06-03 | Buy |
| aablocks | AA02DJM6 | Domagrozumab ≥95%(SDS-PAGE&SEC-HPLC) | 1629605-31-7 | 5mg | $2000 | 2026-06-03 | Buy |
Domagrozumab Chemical Properties, Uses, Production
Uses
Domagrozumab is an anti-myostatin humanized monoclonal antibody with a KD value of 2.6 pM for human myostatin. Domagrozumab induces muscle anabolic activity. Domagrozumab can be used in research of duchenne muscular dystrophy (DMD)[1].
in vivo
Domagrozumab (PF-06252616; 10 and 30 mg/kg; i.v.) increases myostatin levels in a dose-dependent manner and induces skeletal muscle hypertrophy in cynomolgus monkeys[1].
References
[1] St Andre M, et, al. A mouse anti-myostatin antibody increases muscle mass and improves muscle strength and contractility in the mdx mouse model of Duchenne muscular dystrophy and its humanized equivalent, domagrozumab (PF-06252616), increases muscle volume in cynomolgus monkeys. Skelet Muscle. 2017 Nov 9;7(1):25. DOI:10.1186/s13395-017-0141-y
Domagrozumab Preparation Products And Raw materials
Raw materials
Preparation Products
Domagrozumab Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Guangzhou Hongyuan Chemical Co.,Ltd | 15817493340 | 981810490@qq.com | China | 1577 | 58 |
| Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 | 422450190@qq.com | China | 10305 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 27626 | 58 |
| Biolab Reagents | 027-65279366 18108604356 | products@biolabreagent.com | China | 9864 | 58 |
| Wuhan Jingkangen Biomedical Technology Co., Ltd | 13720134139 086-15871494362 13720134139 | orders@jknbiochem.com | China | 7283 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| Wuhan Acumen Bio-Technology Co.,ltd | 027-027-16602739303 16602739303 | 673003916@qq.com | China | 4593 | 58 |
| Shanghai Aladdin Biochemical Technology Co.,Ltd. | 6206333 13167063860 | anhua.mao@aladdin-e.com | China | 43439 | 58 |
| Changsha Fuzhen Biotechnology Co.，LTD | 15111215862 18229892877 | 3062105966@qq.com | China | 5550 | 58 |
