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ChemicalBook >> CAS DataBase List >>L-Prolinamide, N-(9-amino-1-oxononyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-

L-Prolinamide, N-(9-amino-1-oxononyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-

L-Prolinamide, N-(9-amino-1-oxononyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- Structure
L-Prolinamide, N-(9-amino-1-oxononyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- structure
CAS No.
2341796-79-8
Chemical Name:
L-Prolinamide, N-(9-amino-1-oxononyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-
Synonyms
VH032-C7-NH2;VH032-C8-NH2;(S,R,S)-AHPC-C8-NH2;PROTACs Related Compound 4;(S,R,S)-AHPC-C8-NH2 (VH032-C8-NH2);L-Prolinamide, N-(9-amino-1-oxononyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-;(2S,4R)-1-((S)-2-(9-aminononanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide;(2S,4R)-1-((S)-2-(9-Aminononanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide , (S,R,S)-AHPC-C8-NH2
CBNumber:
CB68131663
Molecular Formula:
C31H47N5O4S
Molecular Weight:
585.8
MDL Number:
MFCD32693905
MOL File:
2341796-79-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 06:15:11
Request For Quotation

L-Prolinamide, N-(9-amino-1-oxononyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- Properties

Boiling point 844.3±65.0 °C(Predicted)
Density 1.177±0.06 g/cm3(Predicted)
form Solid
pka 14.08±0.40(Predicted)
color Light yellow to yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319
Precautionary statements  P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

L-Prolinamide, N-(9-amino-1-oxononyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth RTD79679 (S,R,S)-AHPC-C8-NH2 2341796-79-8 100mg $896 2026-06-05 Buy
Biosynth RTD79679 (S,R,S)-AHPC-C8-NH2 2341796-79-8 250mg $1460 2026-06-05 Buy
ChemScene CS-0129754 (S,R,S)-AHPC-C8-NH2 ≥95% 2341796-79-8 50mg $550 2026-06-04 Buy
ChemScene CS-0129754 (S,R,S)-AHPC-C8-NH2 ≥95% 2341796-79-8 100mg $800 2026-06-04 Buy
BroadPharm bp-44658 (S,R,S)-AHPC-C8-NH2 2341796-79-8 25MG $210 2026-05-24 Buy
Product number Packaging Price Buy
RTD79679 100mg $896 Buy
RTD79679 250mg $1460 Buy
CS-0129754 50mg $550 Buy
CS-0129754 100mg $800 Buy
bp-44658 25MG $210 Buy

L-Prolinamide, N-(9-amino-1-oxononyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- Chemical Properties,Uses,Production

Uses

(S,R,S)-AHPC-C8-NH2 (VH032-C8-NH2) is a synthesizedE3 ligase ligand-linker conjugatethat incorporates the VH032 based VHL ligand and a linker used for AKT PROTAC degrader. (S,R,S)-AHPC-C8-NH2 is XF038-164A, example 8, extracted from patent WO2019173516A1[1].

IC 50

VHL

References

[1] Jian Jin, et al. Serine threonine kinase (akt) degradation / disruption compounds and methods of use. Patent WO2019173516A1.

L-Prolinamide, N-(9-amino-1-oxononyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- Preparation Products And Raw materials

Raw materials

Preparation Products

L-Prolinamide, N-(9-amino-1-oxononyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- Suppliers

Global( 11)Suppliers
Supplier Tel Email Country ProdList Advantage
Daicel Chiral Technologies (China)CO.,LTD 021-50460086-9 15921403865 han_yajun@dctc.daicel.com China 7909 65
ChemShuttle, Inc. 0510-83588313-811 18800520310 sales@chemshuttle.com China 2999 62
Jiangsu aikang biomedical research and development co., LTD 025-58859352 17714375163 qzhang@aikonchem.com China 15525 58
Shanghai Kaiwei Chemical Technology Co., Ltd. 021-58461859 15821823057 service@aiviche.com China 49299 58
Shanghai Haohong Pharmaceutical Co., Ltd. 400-8210725 4008210725 malulu@leyan.com China 54996 58
Zhengzhou Converging Chemical Co. LTD 0371-53399770 18037166334 3857571523@qq.com China 7099 58
Henan Mengtai Pharmaceutical Technology Co., Ltd 17634413542 1959525201@qq.com China 9011 58
Dipag (Weinan) Biotechnology Co., Ltd 15114901355 1002921772@qq.com China 190 58
HANGZHOU LAURET BIOTECHOLOGY CO.,LTD 15306536782 3839324846@qq.com China 149 58
Supplier Advantage
Daicel Chiral Technologies (China)CO.,LTD 65
ChemShuttle, Inc. 62
Jiangsu aikang biomedical research and development co., LTD 58
Shanghai Kaiwei Chemical Technology Co., Ltd. 58
Shanghai Haohong Pharmaceutical Co., Ltd. 58
Zhengzhou Converging Chemical Co. LTD 58
Henan Mengtai Pharmaceutical Technology Co., Ltd 58
Dipag (Weinan) Biotechnology Co., Ltd 58
HANGZHOU LAURET BIOTECHOLOGY CO.,LTD 58

2341796-79-8(L-Prolinamide, N-(9-amino-1-oxononyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-)Related Search:

(S,R,S)-Ahpc-C6-NH2 VH 032-linker 11 (2S,4R)-1-((S)-2-(9-aminononanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride VH032-C10-NH2 L-Prolinamide, N-(8-amino-1-oxooctyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-
L-Prolinamide, N-(6-amino-1-oxohexyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-

1of2

PROTACs Related Compound 4 (S,R,S)-AHPC-C8-NH2 (VH032-C8-NH2) (S,R,S)-AHPC-C8-NH2 (2S,4R)-1-((S)-2-(9-aminononanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide VH032-C8-NH2 VH032-C7-NH2 L-Prolinamide, N-(9-amino-1-oxononyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- (2S,4R)-1-((S)-2-(9-Aminononanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide , (S,R,S)-AHPC-C8-NH2 2341796-79-8 C31H47N5O4S