1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-4-[[[4-(hydroxymethyl)phenyl]amino]carbonyl]-5-(1-methylethyl)-3-phenyl-, (βR,δR)-
- CAS No.
- 805241-79-6
- Chemical Name:
- 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-4-[[[4-(hydroxymethyl)phenyl]amino]carbonyl]-5-(1-methylethyl)-3-phenyl-, (βR,δR)-
- Synonyms
- PPD10558;RBx10558;RBx-10558;RBx 10558;PPD-10558;PPD 10558;1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-4-[[[4-(hydroxymethyl)phenyl]amino]carbonyl]-5-(1-methylethyl)-3-phenyl-, (βR,δR)-
- CBNumber:
- CB68366014
- Molecular Formula:
- C34H37FN2O6
- Molecular Weight:
- 588.67
- MDL Number:
- MOL File:
- 805241-79-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-4-[[[4-(hydroxymethyl)phenyl]amino]carbonyl]-5-(1-methylethyl)-3-phenyl-, (βR,δR)- Properties
| Boiling point | 769.1±60.0 °C(Predicted) |
|---|---|
| Density | 1.26±0.1 g/cm3(Predicted) |
| pka | 4.29±0.10(Predicted) |
| form | Solid |
| color | White to off-white |
| FDA UNII | F47K281Y9S |
1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-4-[[[4-(hydroxymethyl)phenyl]amino]carbonyl]-5-(1-methylethyl)-3-phenyl-, (βR,δR)- price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0025506 | Bemfivastatin 99.48% | 805241-79-6 | 5mg | $130 | 2026-06-04 | Buy |
| ChemScene | CS-0025506 | Bemfivastatin 99.48% | 805241-79-6 | 10mg | $211 | 2026-06-04 | Buy |
| ChemScene | CS-0025506 | Bemfivastatin 99.48% | 805241-79-6 | 25mg | $422 | 2026-06-04 | Buy |
| ChemScene | CS-0025506 | Bemfivastatin 99.48% | 805241-79-6 | 50mg | $677 | 2026-06-04 | Buy |
| ChemScene | CS-0025506 | Bemfivastatin 99.48% | 805241-79-6 | 100mg | $1083 | 2026-06-04 | Buy |
1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-4-[[[4-(hydroxymethyl)phenyl]amino]carbonyl]-5-(1-methylethyl)-3-phenyl-, (βR,δR)- Chemical Properties, Uses, Production
Uses
Bemfivastatin (PPD 10558) is an orally active, HMG-CoA Reductase (HMGCR) inhibitor, also known as Statin. Bemfivastatin enhances the activity of liver extraction. Bemfivastatin exhibits little developmental toxicity effects in pregnant rats and rabbits via daily oral doses during organogenesis period. The no observed adverse effect level (NOAEL) are ≥320mg/kg/day for rats developmental toxicity, 12.5mg/kg/day for rabbits maternal toxicity, and 25mg/kg/day for rabbits developmental toxicity, respectively. Bemfivastatin can be used for research on Statin-related hypercholesterolemic myalgia with inability to tolerate statins[1][2].
References
[1] Faqi AS, et al. Developmental toxicity of the HMG-CoA reductase inhibitor (PPD10558) in rats and rabbits. Birth Defects Res B Dev Reprod Toxicol. 2012 Feb;95(1):23-37. DOI:10.1002/bdrb.20337
[2] Wierzbicki A, et al. Drugs in development for the management of dyslipidaemia[J]. Future Prescriber, 2012, 13(2): 12-15.
1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-4-[[[4-(hydroxymethyl)phenyl]amino]carbonyl]-5-(1-methylethyl)-3-phenyl-, (βR,δR)- Preparation Products And Raw materials
Raw materials
Preparation Products
1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-4-[[[4-(hydroxymethyl)phenyl]amino]carbonyl]-5-(1-methylethyl)-3-phenyl-, (βR,δR)- Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38999 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 58 |
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |





