ALC-0159
- CAS No.
- 1849616-42-7
- Chemical Name:
- ALC-0159
- Synonyms
- ALC-0159 ，E0446;mPEG-DTA;mPEG48-TDA;mPEG45-DTA;MPEG2000-DTA;Lipid ALC-0159;mPEG-DTA,MW:2000;mPEG-DTA,MW:3400;mPEG-DTA,MW:5000;mPEG-DTA,MW:10000
- CBNumber:
- CB68366296
- Molecular Formula:
- (C2H4O)nC31H63NO2
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- 1849616-42-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| solubility | DMF: 10 mg/ml; DMF:PBS (pH 7.2) (1:2): 0.3 mg/ml; DMSO: Slightly Soluble; Ethanol: 1 mg/ml |
|---|---|
| form | A solid |
| color | White to off-white |
| FDA UNII | PJH39UMU6H |
ALC-0159 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 34336 | ALC-0159 ≥95% | 1849616-42-7 | 25mg | $109 | 2026-04-30 | Buy |
| Cayman Chemical | 34336 | ALC-0159 ≥95% | 1849616-42-7 | 50mg | $196 | 2026-04-30 | Buy |
| Cayman Chemical | 34336 | ALC-0159 ≥95% | 1849616-42-7 | 100mg | $327 | 2026-04-30 | Buy |
| Cayman Chemical | 34336 | ALC-0159 ≥95% | 1849616-42-7 | 500mg | $1089 | 2026-04-30 | Buy |
| Biosynth | FM180901 | Mpeg-N,N-Ditetradecylacetamide | 1849616-42-7 | 50mg | $206.5 | 2026-06-04 | Buy |
ALC-0159 Chemical Properties, Uses, Production
Physical Form
White to Yellow Solid
Uses
Methoxypoly(ethylene glycol) ditetradecylacetamide can be used in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.
Description
ALC-0159 is a PEG/lipid conjugate (i.e. PEGylated lipid), specifically, it is the N,N-dimyristylamide of 2-hydroxyacetic acid, O-pegylated to a PEG chain mass of about 2 kilodaltons (corresponding to about 45-46 ethylene oxide units per molecule of N,N-dimyristyl hydroxyacetamide). It is a non-ionic surfactant by its nature. It has been deployed in the Pfizer-BioNTech SARS-CoV-2 mRNA vaccine that contains the active ingredient tozinameran.
Uses
ALC-0159, a polyethylene glycol (PEG) lipid conjugate, could be used as vaccine excipient[1].
Application
ALC-0159 is a PEG/lipid conjugate (i.e. PEGylated lipid), specifically, it is the N,N-dimyristylamide of 2-hydroxyacetic acid, O-pegylated to a PEG chain mass of about 2 kilodaltons (corresponding to about 45-46 ethylene oxide units per molecule of N,N-dimyristyl hydroxyacetamide). It is a non-ionic surfactant by its nature.
References
[1] S Moein Moghimi, et al. Allergic Reactions and Anaphylaxis to LNP-Based COVID-19 Vaccines. Mol Ther. 2021 Mar 3;29(3):898-900. DOI:10.1016/j.ymthe.2021.01.030
ALC-0159 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou Chenhong Biotechnology Co., Ltd. | +86-0519-85788828 +86-13775037613 | sales@chemrenpharm.com | China | 4082 | 58 |
| Hunan HuaTeng Pharmaceutical Co., Ltd., | 400-8592883 15367835770 | sales@huatengsci.com | China | 5869 | 58 |
| Nanjing Bairuikang Biotechnology Co., Ltd. | 18168036974 | wangweicss@126.com | China | 1379 | 58 |
| Asymchem Labs. | 17347534561 | liujiaqi11751@asymchem.com.cn | China | 433 | 58 |
| Hefei PolyPrecision Materials Biotechnology Co., Ltd. | 19965439637 | liufei@precpeg.cn | China | 21 | 58 |
| Alabiochem Tech.Co., Ltd. | 512-58900862 400-0707518 | sales@alabiochem.com | China | 988 | 59 |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| Shenzhen HwaGen Pharmaceutical Co.,Ltd | Q:3003761227 17722620669 | liangcong.yi@rafflespt.com | China | 191 | 58 |
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 18149758185 | sales-cpd@caerulumpharma.com | China | 3493 | 58 |
| Shanghai Macklin Biochemical Co.,Ltd. | 15221275939 15221275939 | shenlinxing@macklin.cn | China | 15775 | 55 |
Related articles
- What is the use of the ALC-0159?
- ALC-0159 is a polyethylene glycolated lipid that can be used as a vaccine excipient and has been used in the pharmaceutical fi....
- Mar 18,2024
View Latest Price from ALC-0159 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-12 | ALC-0159
1849616-42-7
|
1KG | 98% | 1000kgs | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2026-07-24 | Methoxypoly(ethylene glycol) ditetradecylacetamide
1849616-42-7
|
1G | 98% | 1 | XIAMEN SINOPEG BIOTECH CO., LTD. | ||
 |
2026-07-24 | Methoxypoly(ethylene glycol) ditetradecylacetamide
1849616-42-7
|
1g | 98% | 1 | XIAMEN SINOPEG BIOTECH CO., LTD. |
-
- ALC-0159
1849616-42-7
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- Methoxypoly(ethylene glycol) ditetradecylacetamide
1849616-42-7
- 98%
- XIAMEN SINOPEG BIOTECH CO., LTD.
-
- Methoxypoly(ethylene glycol) ditetradecylacetamide
1849616-42-7
- 98%
- XIAMEN SINOPEG BIOTECH CO., LTD.
