2'-MECCPA
- CAS No.
- 205171-12-6
- Chemical Name:
- 2'-MECCPA
- Synonyms
- -MeCCPA;2'-MeCCPA;2'-MECCPA;2''-MeCCPA;2' MeCCPA,2'MeCCPA;2-Chloro-N-cyclopentyl-2'-Methyladenosine;2-Chloro-N-cyclopentyl-2′-C-methyladenosine;2'-Chloro-N6-cyclopentyl-2'-methyl adenosine;Adenosine, 2-chloro-N-cyclopentyl-2'-C-methyl-
- CBNumber:
- CB6837734
- Molecular Formula:
- C16H22ClN5O4
- Molecular Weight:
- 383.83
- MDL Number:
- MFCD08703108
- MOL File:
- 205171-12-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 2'-MeCCPA ≥98%(HPLC) | 2281 | 10 | $287 |
| 2''-MeCCPA | M202630 | 1mg | $160 |
| 2'-MeCCPA | B7000 | 10mg | $423 |
| 2'-MECCPA 95.00% | API0009826 | 5MG | $500.7 |
| Boiling point | 643.3±65.0 °C(Predicted) |
|---|---|
| Density | 1.76±0.1 g/cm3(Predicted) |
| storage temp. | Store at +4°C |
| solubility | Soluble to 25 mM in DMSO |
| form | Powder |
| pka | 13.13±0.70(Predicted) |
| color | Off-white to light yellow |
| InChI | 1S/C16H22ClN5O4/c1-16(25)11(24)9(6-23)26-14(16)22-7-18-10-12(19-8-4-2-3-5-8)20-15(17)21-13(10)22/h7-9,11,14,23-25H,2-6H2,1H3,(H,19,20,21) |
| InChIKey | MMPAUXMIDJWGFO-UHFFFAOYSA-N |
| SMILES | Clc1nc2[n](cnc2c(n1)NC4CCCC4)C3OC(C(C3(O)C)O)CO |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
2'-MECCPA price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Tocris | 2281 | 2'-MeCCPA ≥98%(HPLC) | 205171-12-6 | 10 | $287 | 2021-12-16 | Buy |
| TRC | M202630 | 2''-MeCCPA | 205171-12-6 | 1mg | $160 | 2021-12-16 | Buy |
| ApexBio Technology | B7000 | 2'-MeCCPA | 205171-12-6 | 10mg | $423 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0009826 | 2'-MECCPA 95.00% | 205171-12-6 | 5MG | $500.7 | 2021-12-16 | Buy |
2'-MECCPA Chemical Properties,Uses,Production
Uses
2''-MeCCPA is an inhibitor of forskolin-stimulated adenylyl cyclase. It is also a selective A1 adenosine receptor agonist.
Definition
ChEBI: 2-[2-chloro-6-(cyclopentylamino)-9-purinyl]-5-(hydroxymethyl)-3-methyloxolane-3,4-diol is a purine nucleoside.
Biological Activity
Potent and highly selective agonist at A 1 adenosine receptors (K i values are 3.3, 9580, 37600 and 1150 nM for human recombinant A 1 , A 2A , A 2B and A 3 receptors respectively). Acts as a full agonist; inhibits forskolin-stimulated adenylyl cyclase activity in rat cortical membranes with an IC 50 value of 13.1 nM.
in vivo
2’-MeCCPA (1 nM-1 M) at reperfusion significantly reduces infarct size to risk ratio in male Sprague-Dawley rats[1].
IC 50
A1AR
storage
Store at +4°C
2'-MECCPA Preparation Products And Raw materials
Raw materials
Preparation Products
2'-MECCPA Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5742 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32467 | 58 |
| NewCan Biotech Limited | +86-571-86912261 19975279805 | sales@newcanbio.com | China | 9985 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
| Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd | +86-18341751992 +86-15382112998 | 757984502@qq.com | China | 892 | 58 |
| Zhengzhou Chemprize Biotech Co., Ltd. | +86-86-0371-56768238 +8615981919713 | sales@chemprize.com | China | 297 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Shanghai Scibiotron Pharmaceutical Co., Ltd | +86-16621589600 | contact@scibiotron.com | China | 5999 | 58 |
