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Rifamycin Sodium

Rifamycin Sodium Structure
Rifamycin Sodium structure
CAS No.
14897-39-3
Chemical Name:
Rifamycin Sodium
Synonyms
Rifamycin SV s;RIFAMYCIN SODIUM;Rifamycinsodiumsal;RIFAMYCIN SV-SODIUM;RIFAMPICIN SV SODIUM;Rifamycin sodium CRS;rifamycin sodium salt;Rifamycin Na USP/EP/BP;Rifamycin SV Monosodium;RIFAMYCIN,MONOSODIUMSALT
CBNumber:
CB6854850
Molecular Formula:
C37H48NNaO12
Molecular Weight:
721.78
MDL Number:
MFCD00056847
MOL File:
14897-39-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-16 07:06:08
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Rifamycin Sodium Properties

Melting point >215°C (dec.)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility ethanol: soluble50mg/mL
form powder
color Dark Red
Water Solubility Soluble in water, alcohol and dimethyl sulfoxide.
Merck 13,8302
InChIKey DJAAUWJRMPPGDA-HSBICLRHNA-N
SMILES [Na+].CO[C@H]1\C=C\O[C@@]2(C)Oc3c(C)c(O)c4c(O)c(NC(=O)C(C)=C\C=C\[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)cc([O-])c4c3C2=O
FDA UNII 32086GS35Z
UNSPSC Code 51283601
NACRES NA.76

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H319
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P
PPE Eyeshields, Gloves, type N95 (US)
Safety Statements  22-24/25
WGK Germany  3
RTECS  KD1922500
F  8-10-23
Storage Class 11 - Combustible Solids

Rifamycin Sodium price More Price(48)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich R8626 Rifamycin SV sodium salt potency: ≥900units (dry basis) 14897-39-3 1g $131 2026-04-30 Buy
Sigma-Aldrich PHR1664 Rifamycin sodium Pharmaceutical Secondary Standard; Certified Reference Material 14897-39-3 500mg $159 2026-04-30 Buy
Cayman Chemical 21441 Rifamycin SV (sodium salt) ≥98% 14897-39-3 500mg $30 2021-12-16 Buy
Cayman Chemical 21441 Rifamycin SV (sodium salt) ≥98% 14897-39-3 1g $54 2021-12-16 Buy
Usbiological 288896 Rifamycin SV sodium 14897-39-3 50mg $419 2026-06-03 Buy
Product number Packaging Price Buy
R8626 1g $131 Buy
PHR1664 500mg $159 Buy
21441 500mg $30 Buy
21441 1g $54 Buy
288896 50mg $419 Buy

Rifamycin Sodium Chemical Properties, Uses, Production

Chemical Properties

Dark Red Solid

Uses

Rifamycin SV Sodium (Rifaximin EP Impurity C) is a semi-synthetic antibiotic derived from Rifamycin S. (1) Antibacterial (2). Potency >900 units (dry basis).

Uses

Semi-synthetic antibiotic derived from Rifamycin S. Antibacterial. Potency >900 units (dry basis).

Biological Activity

Rifamycin SV inhibits selective (E. coli, B. subtilis) bacterial DNA-dependent RNA polymerase by binding to the polymerase β-subunit, a mechanism similar to rifabutin. It acts as a selective cytochrome P450 3A4 inducer. It is active against Gram-positive bacteria and is moderately active against Gram-negative organisms.

in vivo

Rifamycin (5 mg/day; s.c.; 3 days a week) sodium is effective in mice infected with M. tuberculosis, significantly reducing the number of viable bacteria in the body[4].
Rifamycin (12.5-25 mg/kg; peritoneal lavage) sodium can improve the survival rate of rats with experimental intraperitoneal infection and significantly reduce the number of intraperitoneal bacteria and adhesion formation[6].
Rifamycin (5-40 mg/kg; esophageal gavage; once a day, 5 days a week; 4 weeks) sodium shortens oral treatment duration in a mouse model of Mycobacterium ulcerans disease[8].
Rifamycin (0.1 mL; intraaural administration; twice daily; 10 days) sodium does not cause hearing loss in adult or weanling rats[9].
Rifamycin (1 mg i.v. bolus followed by 4 mg i.v. infusion; 70 min) sodium interferes with three major steps of Bile acid metabolism in rats with intravenous Sodium cholate (HY-N0324A) infusion, resulting in a significant decrease in bile acid uptake and excretion[10].
Rifamycin (10-160 mg/kg; s.c.; single dose) sodium is approximately 11 times less effective than Metronidazole (HY-B0318) in a mouse Bacteroides fragilis thigh infection model[11].

Animal Model:Male Wistar rats (weight 200-250 g), cecal ligation puncture (CLP)-induced intra-abdominal infection model[6]
Dosage:25 mg/kg, 12.5 mg/kg
Administration:Peritoneal lavage
Result:Improved survival from 50% in the control group to 91.7% in the 25 mg/kg group and 100% in the 12.5 mg/kg group.
Significantly reduced adhesion formation.
Showed a greater reduction in bacterial counts in peritoneal fluid (25 mg/kg).

Rifamycin Sodium Preparation Products And Raw materials

Raw materials

RIFAMYCIN SV

Preparation Products

Rifamycin Sodium Suppliers

Global Suppliers ( 284)
Supplier Tel Email Country ProdList Advantage
Hunan ravel Biotechnology Co.,Ltd 18086085632 435918333@qq.com China 1927 58
ZHENGZHOU MINZHONG PHARMACEUTICAL CO.,LTD. -- sale-elva@minzhongcn.com China 11 60
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
XiaoGan ShenYuan ChemPharm co,ltd 15527621225; 15527621225 1791901229@qq.com China 6742 52
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
China Langchem Inc. 0086-21-58956006 China 7798 57
Tianjin heowns Biochemical Technology Co., Ltd. 400 638 7771 sales@heowns.com China 14412 57
Sinopharm Chemical Reagent Co,Ltd. 86-21-63210123 sj_scrc@sinopharm.com China 9791 79
Supplier Advantage
Hunan ravel Biotechnology Co.,Ltd 58
ZHENGZHOU MINZHONG PHARMACEUTICAL CO.,LTD. 60
J & K SCIENTIFIC LTD. 76
Energy Chemical 61
Chemsky（shanghai）International Co.,Ltd. 50
XiaoGan ShenYuan ChemPharm co,ltd 52
Shandong Xiya Chemical Co., Ltd 57
China Langchem Inc. 57
Tianjin heowns Biochemical Technology Co., Ltd. 57
Sinopharm Chemical Reagent Co,Ltd. 79

View Latest Price from Rifamycin Sodium manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Rifamycin sodium salt pictures 2026-09-15 Rifamycin sodium salt
14897-39-3
 $1.00 1g 0.99 20 tons RongNa Biotechnology Co.,Ltd
Rifamycin Sodium pictures 2026-09-15 Rifamycin Sodium
14897-39-3
 1KG 98%min 500kg WUHAN FORTUNA CHEMICAL CO., LTD
Rifamycin sodium pictures 2026-07-15 Rifamycin sodium
14897-39-3
 $30.00-55.00 99.81% 10g TargetMol Chemicals Inc.

Rifamycin Sodium Spectrum

Rifamycin Sodium(14897-39-3)1HNMR

14897-39-3 (Rifamycin Sodium) Related Search:

RIFAMYCIN SV Sodium sulfate Rifamycin O Sodium acetate Disodium phosphonomycin
Sodium bicarbonate Sodium benzoate Sodium hydroxide Sodium chloride Sodium chlorite
Rifampicin Diclofenac sodium RIFAMYCIN RHENIUM(III) CHLORIDE Riboflavin
Rhenium(VII) oxide 8-Chloroadenosine-3',5'-cyclic monophosphorothioate, RP-isomer sodium salt 1,3-Dihydroxynaphthalene

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RIFAMYCIN SODIUM RifaMycin, sodiuM salt (1:1) Rifamycin SV s Rifamycin SV sodium, >=900 IU/mg RIFAMPICIN SV SODIUM RIFAMYCIN SV-SODIUM RIFAMYCIN SV SODIUM SALT RIFAMYCIN SV SODIUM SALT HEXAHYDRATE rifamycin sodium salt Rifamycin SV Monosodium RIFAMYCIN,MONOSODIUMSALT Rifamycin SV hexahydrate sodium salt 2,7-(Epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)furan-1,11(2H)-dione, 5,6,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-, 21-acetate, monosodium salt RifaMycin SV MonosodiuM salt 5,6,9,17,19,21-Hexahydroxy-23-Methoxy-2,4,12,16,18,20,22-heptaMethyl- Rifamycin sodium CRS Rifamycin SV Sodium Salt (Rifaximin EP Impurity C Sodium Salt) (2S,12Z,14E,16S,17S,18R,19R,20R,21S,22R,23S,24E)-21-(Acetyloxy)-5,6,9,17,19-pentahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-2,7-(epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-1,11(2H)-dione sodium salt Rifamycinsodiumsal Rifamycin Na USP/EP/BP Rifamycin Sodium USP/EP/BP TIANFU-CHEM CAS:14897-39-3 Rifamycin sodium salt Rifaximin Impurity C as Sodium Salt Rifaximin EP Impurity C as Sodium Salt Rifamycin Sodium (Rifamycin SV Sodium) Rifamycin sodium, 10 mM in DMSO Rifamycin SV sodium - Bio-X ? Rifaximin EP Impurity C Sodium Salt (Rifamycin SV Sodium Salt) Rifaximin EP Impurity C Sodium Salt (Rifamycin Sodium) 14897-39-3 14897-39-7 C37H47NNaO12 C37H46NNaO126H2O C37H46NO12Na C37H46NNaO12 C37H46NaNO12 BioChemical Antibiotics A to Z Antibiotics Antibiotics N-S Chiral Reagents Intermediates & Fine Chemicals Pharmaceuticals Peptide Synthesis/Antibiotics 14897-39-3