(S)-2-Phenylpyrrolidine
- CAS No.
- 59347-91-0
- Chemical Name:
- (S)-2-Phenylpyrrolidine
- Synonyms
- (S)-2-Phenylpyrrolidine;(2S)-2-Phenylpyrrolidine;(2S)-2α-Phenylpyrrolidine;(S)-2-PHENYLPYRROLIDINE HCl;Pyrrolidine, 2-phenyl-, (2S)-
- CBNumber:
- CB6875464
- Molecular Formula:
- C10H13N
- Molecular Weight:
- 147.22
- MDL Number:
- MFCD06762549
- MOL File:
- 59347-91-0.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2933998090 |
(S)-2-Phenylpyrrolidine price More Price(30)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR932248 | (S)-2-Phenylpyrrolidine 97% | 59347-91-0 | 100mg | $62 | 2026-06-04 | Buy |
| Apolloscientific | OR932248 | (S)-2-Phenylpyrrolidine 97% | 59347-91-0 | 250mg | $85 | 2026-06-04 | Buy |
| Apolloscientific | OR932248 | (S)-2-Phenylpyrrolidine 97% | 59347-91-0 | 1g | $315 | 2026-06-04 | Buy |
| Apolloscientific | OR932248 | (S)-2-Phenylpyrrolidine 97% | 59347-91-0 | 5g | $1102 | 2026-06-04 | Buy |
| Activate Scientific | AS7522-A | (S)-2-Phenylpyrrolidine 97%EE | 59347-91-0 | 1g | $365 | 2026-06-04 | Buy |
(S)-2-Phenylpyrrolidine Chemical Properties,Uses,Production
Description
(S)-2-Phenylpyrrolidine is an amine that has been synthesized for use in research. It is chiral and can exist as either the levorotatory or dextrorotatory form. It interacts with the tropomyosin receptor, which is a protein found on the surface of muscle cells. This interaction prevents calcium ions from binding to tropomyosin, thereby preventing muscle contraction.
Uses
(S)-2-Phenylpyrrolidine has been shown to be effective in treating neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease. Research also suggests that this drug may be effective at preventing aldehyde toxicity mediated by the enzyme acetaldehyde dehydrogenase 2 (ALDH2).
Reactions
(S)-2-Phenylpyrrolidine could be react with N-{3-nitro-4-[(oxan-4-ylmethyl)amino]benzenesulfonyl}-4-{2-oxo-7-azaspiro[3.5]nonan-7- y l}-2-[( 11 R, 15S)-4-{[2-(trimethy Isi ly l)ethoxy]methy I}- 13, 16-dioxa-2,4, 10- triazatetracyclo[7.7.0.0A{3,7}.0A{11,15}]hexadeca-1(9),2,5,7-tetraen-10-yl]benzamide to synthsize a intermediate of BCL-2 inhibitor. It can also be use in the preparation of the Inhibitors of ubiquitin specific protease 19 (USP19) through amine group coupling.
Synthesis
Into a 100 mL round-bottom flask were added tert-butyl (2S)- 2-phenylpyrrolidine-1-carboxylate (70 mg, 0.3 mmol, 1.0 eq) and CHsCh .0 mL), TFA (0.5 mL) at 25°C. The resulting mixture was stirred for 3 hours at 25°C. The resulting mixture was concentrated under reduced pressure. This resulted in (S)-2-Phenylpyrrolidine (40 mg, 96.0%) as colorless oil.
(S)-2-Phenylpyrrolidine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Tetranov Biopharm | 13526569071 | sales@leadmedpharm.com | China | 7882 | 64 |
| Acesys Pharmatech | 18860950986 | tangmanman@zenjipharma.com | China | 1731 | 55 |
| Doly Chemical CO.,LTD. | 021-34716221 15800796336 | sales@dolypharm.com | China | 294 | 55 |
| AstaTech (Chengdu) Pharma. Co., Ltd. | 15928766785 15928766785 | wupengcheng@astatech.cn | China | 1995 | 55 |
| Shijiazhuang Lickon PharmaTech Co., Ltd. | 031185291771 13832391721 | yaofeng2005@163.com | China | 947 | 58 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| LABTER PHARMATECH(BEIJING) CO.,LTD | 010-56330744 18310155299 | sales@labter.com.cn | China | 19999 | 55 |
| Cool Pharm, Ltd | 021-60455363 18019463053 | sales@coolpharm.com | China | 8455 | 58 |
| SanoChem (Chengdu) Tech. Co., Ltd. | 28-87999436 02887999436 | sales@sano-chem.com | China | 3792 | 55 |
View Lastest Price from (S)-2-Phenylpyrrolidine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-08-08 | (2S)-2-phenylpyrrolidine
59347-91-0
|
$3.00 | 1KG | 99% | 100kg | Career Henan Chemical Co |
-
- (2S)-2-phenylpyrrolidine
59347-91-0
- $3.00
- 99%
- Career Henan Chemical Co
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