2,3-dichloro-6-nitroaniline
- CAS No.
- 65078-77-5
- Chemical Name:
- 2,3-dichloro-6-nitroaniline
- Synonyms
- 2,3-Dichloro-6-nitrobenzenamine;Benzenamine,2,3-dichloro-6-nitro-
- CBNumber:
- CB6876719
- Molecular Formula:
- C6H4Cl2N2O2
- Molecular Weight:
- 207.01
- MDL Number:
- MFCD00110529
- MOL File:
- 65078-77-5.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
2,3-dichloro-6-nitroaniline price More Price(17)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | D436775 | 2,3-Dichloro-6-nitroaniline | 65078-77-5 | 50mg | $80 | 2021-12-16 | Buy |
| TRC | D436775 | 2,3-Dichloro-6-nitroaniline | 65078-77-5 | 250mg | $110 | 2021-12-16 | Buy |
| TRC | D436775 | 2,3-Dichloro-6-nitroaniline | 65078-77-5 | 1g | $275 | 2021-12-16 | Buy |
| TRC | D436775 | 2,3-Dichloro-6-nitroaniline | 65078-77-5 | 2.5g | $525 | 2021-12-16 | Buy |
| ChemScene | CS-0060318 | 2,3-Dichloro-6-nitroaniline | 65078-77-5 | 5g | $356 | 2021-12-16 | Buy |
2,3-dichloro-6-nitroaniline Chemical Properties,Uses,Production
Uses
2,3-Dichloro-6-nitroaniline is used as a reagent in the synthesis of 3-alkyl-, 3-halomethyl- and 3-carboxyethylquinoxaline-2-ones which have potential antimicrobial activity.
Synthesis
17700-09-3
65078-77-5
General procedure for the synthesis of 2,3-dichloro-6-nitroaniline from 2,3,4-trichloronitrobenzene: 4000 g of chlorobenzene, 10121 g of ammonia (40% by mass) and 2,3,4-trichloronitrobenzene (1:3 by weight with ammonia) prepared in step S1 were pumped into an autoclave. The reaction temperature was raised to 145 °C under stirring conditions and the reaction was held at this temperature for 5 hours. Upon completion of the reaction, the reaction mixture was cooled to room temperature with cooling water. Subsequently, the material was separated by hydraulic filtration until layered. After distillation to recover the chlorobenzene layer, calcium oxide was added to the ammonia layer to convert ammonium ions to free ammonia. Next, the mixture was heated and evaporated and the free ammonia in the vapor was absorbed by water and recycled for the preparation of 2,3-dichloro-6-nitroaniline. The filter cake was washed to neutrality with hot water at a temperature of 40-60 °C and dried to give the target product 2,3-dichloro-6-nitroaniline. The product was analyzed by liquid chromatography with 97.9% purity and 99.2% yield.
References
[1] Patent: CN106854162, 2017, A. Location in patent: Paragraph 0033; 0034; 0036; 0037-0039; 0041-0044; 0046; 0047
[2] Patent: WO2016/40764, 2016, A1. Location in patent: Page/Page column 50; 51
[3] Journal of Medicinal Chemistry, 1996, vol. 39, # 4, p. 881 - 891
[4] Justus Liebigs Annalen der Chemie, 1879, vol. 196, p. 222
[5] Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, 1879, vol. 11, p. 332
2,3-dichloro-6-nitroaniline Preparation Products And Raw materials
Raw materials
Preparation Products
2,3-dichloro-6-nitroaniline Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29800 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 12233 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14360 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19987 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
| Aromsyn Co., Ltd. | +86-0571-85585865 +8613336024896 | CB@aromsyn.com | China | 19183 | 58 |
View Lastest Price from 2,3-dichloro-6-nitroaniline manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-08 | 2,3-dichloro-6-nitroaniline
65078-77-5
|
US $2.00 / KG | 1g | 98%MIN | ASK | Career Henan Chemical Co |
-
- 2,3-dichloro-6-nitroaniline
65078-77-5
- US $2.00 / KG
- 98%MIN
- Career Henan Chemical Co
