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ChemicalBook >> CAS DataBase List >>4-Bromo-2,6-diaminopyridine

4-Bromo-2,6-diaminopyridine

4-Bromo-2,6-diaminopyridine Structure
4-Bromo-2,6-diaminopyridine structure
CAS No.
329974-09-6
Chemical Name:
4-Bromo-2,6-diaminopyridine
Synonyms
4-Bromo-2,6-diaminopyridine;4-Bromopyridine-2,6-diamine;2,6-Diamino-4-bromopyridine;4-bromo-2,6-Pyridinediamine;2,6-Pyridinediamine, 4-bromo-;4-Bromo-2,6-diaminopyridine ,98%;TIANFU CHEM-- 4-Bromo-2,6-diaminopyridine;methyl 2-amino-5-bromo-3,4-difluorobenzoate;4-Bromo-2,6-diaminopyridine ISO 9001：2015 REACH
CBNumber:
CB6947079
Molecular Formula:
C5H6BrN3
Molecular Weight:
188.03
MDL Number:
MFCD04115308
MOL File:
329974-09-6.mol
MSDS File:
SDS
Last updated:2026-05-28 01:20:00
Product description Number Pack Size Price
4-BROMO-2,6-DIAMINOPYRIDINE 98% 56898 1G $47
4-BROMO-2,6-DIAMINOPYRIDINE 98% 56898 5G $233
4-BROMO-2,6-DIAMINOPYRIDINE 98% 56898 25G $973
4-Bromo-2,6-diaminopyridine 97% B41056 100mg $55
4-Bromo-2,6-diaminopyridine 97% B41056 250mg $59
More product size
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4-Bromo-2,6-diaminopyridine Properties

Melting point 126 °C
Boiling point 352.7±37.0 °C(Predicted)
Density 1.818±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
form powder
pka 5.13±0.35(Predicted)
color White
InChI InChI=1S/C5H6BrN3/c6-3-1-4(7)9-5(8)2-3/h1-2H,(H4,7,8,9)
InChIKey KXHPZYVKCDTIHE-UHFFFAOYSA-N
SMILES C1(N)=NC(N)=CC(Br)=C1

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
HazardClass  IRRITANT
HS Code  29339900

4-Bromo-2,6-diaminopyridine price More Price(47)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AstaTech 56898 4-BROMO-2,6-DIAMINOPYRIDINE 98% 329974-09-6 1G $47 2026-04-30 Buy
AstaTech 56898 4-BROMO-2,6-DIAMINOPYRIDINE 98% 329974-09-6 5G $233 2026-04-30 Buy
AstaTech 56898 4-BROMO-2,6-DIAMINOPYRIDINE 98% 329974-09-6 25G $973 2026-04-30 Buy
Synthonix B41056 4-Bromo-2,6-diaminopyridine 97% 329974-09-6 100mg $55 2026-05-06 Buy
Synthonix B41056 4-Bromo-2,6-diaminopyridine 97% 329974-09-6 250mg $59 2026-05-06 Buy
Product number Packaging Price Buy
56898 1G $47 Buy
56898 5G $233 Buy
56898 25G $973 Buy
B41056 100mg $55 Buy
B41056 250mg $59 Buy

4-Bromo-2,6-diaminopyridine Chemical Properties,Uses,Production

Chemical Properties

Off-white solid

Uses

4-Bromo-2,6-diaminopyridine is a versatile reactant used in the preparation of a uracil DNA glycosylase which is a DNA repair enzyme with selective recognition of uracil and its derivatives.

Synthesis

Sodium hydroxide

1310-73-2

Trifluoroacetic acid

76-05-1

2,6-Pyridinedicarbonyl diazide, 4-bromo-

329974-10-9

4-Bromo-2,6-diaminopyridine

329974-09-6

c) Synthesis of 4-bromo-2,6-diaminopyridine 1 g (3.65 mmol) of 4-bromo-pyridine-2,6-dicarboxylic acid dihydrazide was suspended in 32 mL of water and 1.6 mL of 37% HCl was added at room temperature.The reaction mixture was cooled down to 0 °C and 554 mg of NaNO2 dissolved in 2.4 mL of water was slowly added keeping the reaction temperature below 2 °C. The reaction temperature was adjusted to 8 °C by filtration. After completion of the reaction, the pH was adjusted to 8 with saturated NaHCO3 solution, the white precipitate was collected by filtration and washed with cold water. The solid residue was dissolved in CHCl3 and dried with MgSO4. The filtrate was concentrated at 20 °C to give 920 mg (85%) white solid. 450 mg (1.5 mmol) of the above white solid was suspended in a solvent mixture of toluene/tert-butanol (5:1) and refluxed for 12 hours. After removing the solvent under reduced pressure, 5 mL of toluene and 0.3 mL of trifluoroacetic acid were added and reflux was continued for 2 hours. The solvent was again removed under reduced pressure and the residue was purified by rapid chromatography on silica gel using dichloromethane/methanol (9:1) as eluent. After elution the solvent was removed under reduced pressure and the residue was suspended in diethyl ether and a 1N NaOH solution was added to release 4-bromo-2,6-diaminopyridine. The organic phase was dried over Na2SO4 and the solvent was removed under reduced pressure to give 192 mg (67%) of the target product. Mass spectrometry analysis showed m/e: 188 (M+, 100%).

References

[1] Patent: US6355653, 2002, B1. Location in patent: Page column 27-28

4-Bromo-2,6-diaminopyridine Preparation Products And Raw materials

Raw materials

Ammonium hydroxide PHOSPHORUS PENTABROMIDE Ethanol N,N-Dimethylformamide Potassium hydroxide
Acetone Diethyl oxalate Chloroform Sodium ethoxide Sodium nitrite
Hydrochloric acid Bromine Potassium permanganate Methanol 2,6-DIMETHYL-PYRIDIN-4-YLAMINE
Activated carbon Sulfuric acid

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Preparation Products

4-Bromo-2,6-diaminopyridine Suppliers

Global( 137)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		+8613336195806 sales@capot.com China 29640 60
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21587 55
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29815 58
Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715 admin@nexconn.com China 10403 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
Wuhan Chemwish Technology Co., Ltd 		027-67849912 sales@chemwish.com CHINA 10821 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49979 58
Neostar United (Changzhou) Industrial Co., Ltd. 		+86-0519-85551759 +8613506123987 marketing1@neostarunited.com China 8828 58
ANHUI WITOP BIOTECH CO., LTD 		+8615255079626 eric@witopchemical.com China 23541 58
Dayang Chem (Hangzhou) Co.,Ltd. 		+86-0571-88938639 +8617705817739 info@dycnchem.com China 52705 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
Henan Tianfu Chemical Co.,Ltd. 		55
career henan chemical co 		58
Shenzhen Nexconn Pharmatechs Ltd 		58
Alchem Pharmtech,Inc. 		58
Wuhan Chemwish Technology Co., Ltd 		58
CONIER CHEM AND PHARMA LIMITED 		58
Neostar United (Changzhou) Industrial Co., Ltd. 		58
ANHUI WITOP BIOTECH CO., LTD 		58
Dayang Chem (Hangzhou) Co.,Ltd. 		58

View Lastest Price from 4-Bromo-2,6-diaminopyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Bromo-2,6-diaminopyridine pictures 2020-05-13 4-Bromo-2,6-diaminopyridine
329974-09-6
 1KG 99.0% 500 MT Shaanxi Dideu Medichem Co. Ltd
4-Bromo-2,6-diaminopyridine pictures 2019-07-06 4-Bromo-2,6-diaminopyridine
329974-09-6
 $1.00 1kg 98% 100KG Career Henan Chemical Co

4-Bromo-2,6-diaminopyridine Spectrum

4-Bromo-2,6-diaminopyridine(329974-09-6)1HNMR

329974-09-6(4-Bromo-2,6-diaminopyridine)Related Search:

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HYDRAZINE 2-Aminopyridine 4-Bromo-2,5-dichloropyridine 4-BroMo-2,5-difluoropyridine Bromine
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4-Bromo-2,6-diaminopyridine ,98% 2,6-Diamino-4-bromopyridine 4-Bromopyridine-2,6-diamine 4-Bromo-2,6-diaminopyridine methyl 2-amino-5-bromo-3,4-difluorobenzoate 2,6-Pyridinediamine, 4-bromo- 4-bromo-2,6-Pyridinediamine 4-Bromo-2,6-diaminopyridine ISO 9001：2015 REACH TIANFU CHEM-- 4-Bromo-2,6-diaminopyridine 329974-09-6