IGF-1 LR3
- CAS No.
- 946870-92-4
- Chemical Name:
- IGF-1 LR3
- Synonyms
- LR3-IGF1;IGF LR3-1;KL80;CL281;IGF-1 LR3;IDF-1 LR3;IGF-1LR3 8866;IGF-1Lr3 Igtropin;IGF-1 LR3 0.1mg /1mg;LR3-IGF1 (100mcg/vial
- CBNumber:
- CB6947862
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P280-P305+P351+P338 |
IGF-1 LR3 Chemical Properties,Uses,Production
Mechanism of action
IGF-1 LR3 binds to cell receptors in the muscle cells and activates cell communication, which then improves the growth rate of muscles.IGF-1 LR3 obstructs the movement of glucose into the body’s cells. This facilitates fat burning and the use of fat in the body for the production of energy. IGF-1 LR3 has a life in the body for about 20-30 hours and therefore enhance the growth amount of muscle for a whole day.
Structure
IGF-1 LR3 is a recombinant synthetic growth factor of ~9.1 kDa, a single polypeptide chain containing 83 amino acid residues. It is an analog of IGF-1 comprised of the complete IGF-1 sequence, with an Arginine substitution for the third position Glutamic acid and a 13 amino acid length N terminus peptide extension. It has been engineered for higher biological potency in vitro, with an increased half-life. This recombinant IGF-1 LR3 product is a highly potent growth factor ideal for stem cell research and cell manufacturing applications, including cells of the ectoderm linage (oligodendrocytes, motor neurons) and mesoderm linage (osteocytes, chondrocytes, and muscle cells).
Description
Long arginine 3-IGF-1, abbreviated as IGF-1 LR3 or LR3-IGF-1, is a synthetic protein and lengthened analogue of human insulin-like growth factor 1 (IGF-1). It differs from native IGF-1 in that it possesses an arginine instead of a glutamic acid at the third position in its amino acid sequence ("arginine 3"), and also has an additional 13 amino acids at its N-terminus (MFPAMPLLSLFVN) ("long"), for a total of 83 amino acids (relative to the 70 of IGF-1).
Uses
The consequences of these modifications are that IGF-1 LR3 retains the pharmacological activity of IGF-1 as an agonist of the IGF-1 receptor, has very low affinity for the insulin-like growth factor-binding proteins (IGFBPs), and has improved metabolic stability.As a result, it is approximately three times more potent than IGF-1,and possesses a significantly longer half-life of about 20–30 hours (relative to IGF-1's half-life of about 12–15 hours).
benefits
Based on the literature, IGF1-LR3 has been shown to:
Increase Fat Loss
Aid in the development of lean muscle mass
Add protection against muscle wasting
Reduce inflammation
Side effects
Some possible side effects of IGF-1 LR3 may include the following: muscle and joint pain, nausea, headaches, hypoglycemia (usually when IGF-1 LR3 is administered in continuous high doses) and may be associated with increased risk of developing some cancers.
IGF-1 LR3 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hydebio Labs Co., Limited | 15961755722 | mrkt@hydebiolabs.com | China | 145 | 58 |
| Shanxi Nuocheng Biotechnology Co., Ltd | 17835231871 | 572710841@qq.com | China | 7836 | 58 |
| Wuxi Zhongkun Biochemical Technology Co., Ltd. | 0510-85629785 18013409632; | sales@reading-chemicals.com | China | 15165 | 58 |
| Chizhou Kailong Import and Export Trade Co., Ltd. | xg01_gj@163.com | China | 9413 | 50 | |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Zhuhai JiaYi Biological Technology Co., Ltd. | 18578209868 2355327026 | steroidbest@hotmail.com | China | 6488 | 58 |
| Nanjing crow LuNing pharmaceutical technology co., LTD | 13382066392 | CHINA | 4851 | 58 | |
| Beijing OKA biological technology co., LTD | 010-62971590 18548936886 | 3462612863@qq.com | China | 10061 | 58 |
| Dideu Industries Group Limited | +8617392712697 | 1022@dideu.com | China | 29091 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +86-17531190177 | faithe@yan-xi.com | China | 5838 | 58 |
Related articles
- Mechanism and Side Effects of IGF-1 LR3
- The consequences of these modifications are that IGF-1 LR3 retains the pharmacological activity of IGF-1 as an agonist of the ....
- Aug 1,2022
- Application and benefits of IGF-1 LR3
- IGF-1 LR3 is a polypeptide long-chain amino acid peptide hormone. Insulin-like Growth Factor (IGF-1 Long-Arginine 3), an 83-am....
- Feb 28,2022
Related Questions
Ask a questionView Lastest Price from IGF-1 LR3 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-13 | IGF-1LR3
946870-92-4
|
$20.00 | 1box | 99 | Ningbo Qingteng Plastic Cost.,Ltd. | ||
 |
2026-09-13 | IGF-1LR3
946870-92-4
|
$20.00 | 1box | 99 | Ningbo Qingteng Plastic Cost.,Ltd. | ||
 |
2026-09-13 | IGF-1LR3
946870-92-4
|
$20.00 | 1box | 99 | Ningbo Qingteng Plastic Cost.,Ltd. |
