ChemicalBook >> CAS DataBase List >>GM-608
GM-608
- CAS No.
- 725715-18-4
- Chemical Name:
- GM-608
- Synonyms
- Alirinetide;GM-608;GM-607;GM-606;GM-605;GM-604;GM-603;GM-602;GM608,GM 608;L-Arginine, L-phenylalanyl-L-seryl-L-arginyl-L-tyrosyl-L-alanyl-
- CBNumber:
- CB69778032
- Molecular Formula:
- C36H54N12O9
- Molecular Weight:
- 798.89
- MDL Number:
- MOL File:
- 725715-18-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-07-17 09:03:53
| Density | 1.46±0.1 g/cm3(Predicted) |
|---|---|
| form | Solid |
| pka | 3.34±0.10(Predicted) |
| color | White to off-white |
| FDA UNII | 6BK9OEG8CC |
GM-608 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0027391 | Alirinetide 99.94% | 725715-18-4 | 5mg | $92 | 2026-06-04 | Buy |
| ChemScene | CS-0027391 | Alirinetide 99.94% | 725715-18-4 | 10mg | $146 | 2026-06-04 | Buy |
| ChemScene | CS-0027391 | Alirinetide 99.94% | 725715-18-4 | 25mg | $303 | 2026-06-04 | Buy |
| ChemScene | CS-0027391 | Alirinetide 99.94% | 725715-18-4 | 50mg | $487 | 2026-06-04 | Buy |
| ChemScene | CS-0027391 | Alirinetide 99.94% | 725715-18-4 | 100mg | $780 | 2026-06-04 | Buy |
GM-608 Chemical Properties, Uses, Production
Uses
Alirinetide (GM604) is an oligopeptide containing 6 amino acids. Alirinetide can cross the blood-brain barrier and can be used for the research of multiple neurodegenerative diseases[1].
in vivo
Alirinetide (GM604) (0-20 mg/kg; i.v.; twice daily for 5 days) improves behavioral, biochemical, and histological features in the 6-OHDA mouse model[1].
| Animal Model: | C57BL/6 mice, 6-hydroxydopamine (6-OHDA) mouse model[1] |
| Dosage: | 0, 1, 5, 10 or 20 mg/kg |
| Administration: | Intravenous injection, twice daily for 5 days |
| Result: | Almost completely abrogated 6-OHDA effects at the highest dose, leading to improved motor performance, increased numbers of TH-positive neurons in the substantia nigra, and increased brain levels of dopamine, 3,4-Dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA). |
References
[1] Swindell W R, et al. GM604 for Parkinson's Disease treatment: Pre-clinical findings and results from a pilot placebo-controlled trial. F1000Research, 2017, 6.
GM-608 Preparation Products And Raw materials
Raw materials
Preparation Products
GM-608 Suppliers
Global Suppliers ( 13)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu Youngshe Chemical Co., Ltd. | +86-17380623303 | Caroline@youngshechem.com | China | 4725 | 58 |
| Hangzhou Peptidego Biotech Co.,Ltd. | 0571-87213919 15967184799 | Eric@peptidego.com | China | 7872 | 58 |
| Shaoxing Junyu Biotechnology Co., LTD | 0571-0571-88211921 19105816207 | sales4@gotopbio.com | China | 5135 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Hangzhou Sinoda Pharmaceutical Technology Co. LTD | 0571-87213919 17306812703 | 3007955328@qq.com | China | 7446 | 58 |
| Shanghai HongTide Biotechnology Co.,Ltd. | 15318089928 | alex@hanhonggroup.com | China | 4604 | 58 |
| Zhejiang Jiekun Biotechnology Co., Ltd | 0571-88211921 15397062932 | sales1@gotopbio.com | China | 4864 | 58 |
| Taiyuan Bailihengkang Biotechnology Co., Ltd | 19135651983 | 18611134419@163.com | China | 4416 | 58 |
| YantaiBio | 13758194781; 13758194781 | 764619768@qq.com | China | 1773 | 58 |
| Fuan Bio | 15002819872 | 2845971812@qq.com | China | 2103 | 58 |
725715-18-4 (GM-608) Related Search:
L-Arginine, L-phenylalanyl-L-seryl-L-arginyl-L-tyrosyl-L-alanyl-
GM-602
GM-603
GM-604
GM-605
GM-606
GM-607
GM-608
GM608,GM 608
Alirinetide
725715-18-4
C36H54N12O9
