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5-Pyrimidinamine, 2-chloro-4-methyl- (9CI)

5-Pyrimidinamine, 2-chloro-4-methyl- (9CI) structure

CAS No.: 20090-69-1

Chemical Name:: 5-Pyrimidinamine, 2-chloro-4-methyl- (9CI)

Synonyms: NSC 243816;2-Chloro-4-MethylpyriMidin-5-aMine;5-Amino-2-chloro-4-methylpyrimidine;5-PyriMidinaMine, 2-chloro-4-Methyl-;2-chloro-4-methyl-pyrimidin-5-ylamine;5-Pyrimidinamine, 2-chloro-4-methyl- (9CI);5-Pyrimidinamine, 2-chloro-4-methyl- (9CI) ISO 9001：2015 REACH

CBNumber:: CB71082097

Molecular Formula:: C5H6ClN3

Molecular Weight:: 143.57

MDL Number:: MFCD12923128

MOL File:: 20090-69-1.mol

MSDS File:: SDS

Last updated:2025-10-14 17:29:02

Product description	Number	Pack Size	Price
5-Amino-2-chloro-4-methylpyrimidine	A595670	100mg	$65
2-Chloro-4-methylpyrimidin-5-amine	FC153804	250mg	$110
2-Chloro-4-methylpyrimidin-5-amine	W4245	250mg	$119
2-Chloro-4-methylpyrimidin-5-amine	FC153804	500mg	$190
2-Chloro-4-methylpyrimidin-5-amine	FC153804	1g	$332.5
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5-Pyrimidinamine, 2-chloro-4-methyl- (9CI) Properties

Melting point	93.5℃
Boiling point	309.4±22.0 °C(Predicted)
Density	1.349±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
pka	0.36±0.29(Predicted)
Appearance	Off-white to light yellow Solid
InChI	InChI=1S/C5H6ClN3/c1-3-4(7)2-8-5(6)9-3/h2H,7H2,1H3
InChIKey	RZAKVHVZRSQZEQ-UHFFFAOYSA-N
SMILES	C1(Cl)=NC=C(N)C(C)=N1

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS06
Signal word	Danger
Hazard statements	H301-H319-H331-H401
Precautionary statements	P264-P270-P301+P310-P321-P330-P405-P501-P280-P305+P351+P338-P337+P313-P261-P271-P304+P340-P311-P403+P233-P273
HS Code	2933599590

5-Pyrimidinamine, 2-chloro-4-methyl- (9CI) price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	A595670	5-Amino-2-chloro-4-methylpyrimidine	20090-69-1	100mg	$65	2021-12-16	Buy
Biosynth Carbosynth	FC153804	2-Chloro-4-methylpyrimidin-5-amine	20090-69-1	250mg	$110	2021-12-16	Buy
AK Scientific	W4245	2-Chloro-4-methylpyrimidin-5-amine	20090-69-1	250mg	$119	2021-12-16	Buy
Biosynth Carbosynth	FC153804	2-Chloro-4-methylpyrimidin-5-amine	20090-69-1	500mg	$190	2021-12-16	Buy
Biosynth Carbosynth	FC153804	2-Chloro-4-methylpyrimidin-5-amine	20090-69-1	1g	$332.5	2021-12-16	Buy

Product number	Packaging	Price	Buy
A595670	100mg	$65	Buy
FC153804	250mg	$110	Buy
W4245	250mg	$119	Buy
FC153804	500mg	$190	Buy
FC153804	1g	$332.5	Buy

5-Pyrimidinamine, 2-chloro-4-methyl- (9CI) Chemical Properties,Uses,Production

Synthesis

13162-26-0

5-Pyrimidinamine, 2-chloro-4-methyl- (9CI)

20090-69-1

The general procedure for the synthesis of 5-amino-2-chloro-4-methylpyrimidine from 2,4-dichloro-5-nitro-6-methylpyrimidine was as follows: to a stirred methanol (100 mL) solution of 2,4-dichloro-6-methyl-5-nitropyrimidine (10 g, 48.1 mmol) and ammonium chloride (25.7 g, 481 mmol) under nitrogen protection was added in batches zinc powder ( 31.4 g, 481 mmol). The reaction mixture was stirred at 70 °C for 50 hours. After completion of the reaction, the mixture was filtered and the filtrate was concentrated under vacuum. The residue was purified by silica gel column chromatography (eluent: dichloromethane/methanol, 30:1). All fractions containing the target product were collected and detected by thin layer chromatography (unfolding agent: ethyl acetate/petroleum ether, 1:1, Rf=0.6), combined and concentrated to give 2-chloro-4-methylpyrimidin-5-amine (2 g, 13.93 mmol, 29.0% yield) as a light yellow solid. The product was characterized by 1H NMR (400 MHz, CDCl3): δ 7.95 (s, 1H), 3.66 (s, 2H), 2.88 (s, 3H); ESI-MS m/z: 144.2 ([M+H]+).

References

[1] Patent: WO2016/37578, 2016, A1. Location in patent: Page/Page column 138
[2] Chemische Berichte, 1901, vol. 34, p. 1242
[3] Yakugaku Zasshi, 1942, vol. 62, p. 315,333; dtsch. Ref. S. 95, 106
[4] Chem.Abstr., 1951, p. 5150
[5] Patent: EP2100894, 2009, A1. Location in patent: Page/Page column 20

5-Pyrimidinamine, 2-chloro-4-methyl- (9CI) Preparation Products And Raw materials

Raw materials

2,4-Dichloro-6-methyl-5-nitropyrimidine 2,4-DICHLORO-5-AMINO-6-METHYLPYRIMIDINE Methanol ZINC Ammonium chloride

Preparation Products

1H-Pyrazolo[4,3-d]pyriMidine, 5-chloro- 5-Pyrimidinamine, 4-methyl-2-(methylthio)-

5-Pyrimidinamine, 2-chloro-4-methyl- (9CI) Suppliers

Global( 105)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29795	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
Wuxi Rejoys chemical Technology Co., Ltd.	0510-86103381	sales@rejoyschem.com	CHINA	976	58
Shanghai UCHEM Inc.	+862156762820 +86-13564624040	sales@myuchem.com	China	8800	58
KARMEL TECHNOLOGY (HK) CO.,LIMITED	+8618795957998	karmelhk@126.com	CHINA	2886	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	18895	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850	market18@leapchem.com	China	43333	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
Alchem Pharmtech,Inc.	58
career henan chemical co	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Wuxi Rejoys chemical Technology Co., Ltd.	58
Shanghai UCHEM Inc.	58
KARMEL TECHNOLOGY (HK) CO.,LIMITED	58
Dideu Industries Group Limited	58
HANGZHOU LEAP CHEM CO., LTD.	58

View Lastest Price from 5-Pyrimidinamine, 2-chloro-4-methyl- (9CI) manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2025-11-18	5-Pyrimidinamine, 2-chloro-4-methyl- (9CI) 20090-69-1	US $1.10 / g	1g	99.00%	100 Tons Min	Dideu Industries Group Limited
	2020-01-13	5-Pyrimidinamine, 2-chloro-4-methyl- (9CI) 20090-69-1	US $5.50 / KG	1KG	98%min	1kg-100kg	Career Henan Chemical Co

5-Pyrimidinamine, 2-chloro-4-methyl- (9CI)
20090-69-1
US $1.10 / g
99.00%
Dideu Industries Group Limited

5-Pyrimidinamine, 2-chloro-4-methyl- (9CI)
20090-69-1
US $5.50 / KG
98%min
Career Henan Chemical Co

5-Pyrimidinamine, 2-chloro-4-methyl- (9CI) Spectrum

5-Pyrimidinamine, 2-chloro-4-methyl- (9CI)(20090-69-1)¹HNMR

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5-Pyrimidinamine, 2-chloro-4-methyl- (9CI) 5-Amino-2-chloro-4-methylpyrimidine 2-chloro-4-methyl-pyrimidin-5-ylamine 2-Chloro-4-MethylpyriMidin-5-aMine NSC 243816 5-PyriMidinaMine, 2-chloro-4-Methyl- 5-Pyrimidinamine, 2-chloro-4-methyl- (9CI) ISO 9001：2015 REACH 20090-69-1 PYRIMIDINE