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(S)-(+)-2-Amino-1-butanol

CAS No.
5856-62-2
Chemical Name:
(S)-(+)-2-Amino-1-butanol
Synonyms
(S)-2-AMinobutan-1-ol;2-AMINO-1-BUTANOL;L-2-Aminobutanol;tube1179;(S)-2-AMINOBUTANOL; D-amino-2-butanol;D-2-AMINO-1-BUTANOL;(S)(+)-2-AMINOBUTANOL;(+)-2-Amino-1-butanol;D(+)-2-AMINO-1-BUTANOL
CBNumber:
CB7108620
Molecular Formula:
C4H11NO
Molecular Weight:
89.14
MDL Number:
MFCD00064418
MOL File:
5856-62-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-12 09:20:59
Product description Number Pack Size Price
(S)-(+)-2-Amino-1-butanol ≥98% 132527 5g $123
(S)-(+)-2-Amino-1-butanol ≥98% 132527 1g $58.6
(S)-(+)-2-Amino-1-butanol >98.0%(GC)(T) A0973 1mL $33
(S)-(+)-2-Amino-1-butanol >98.0%(GC)(T) A0973 5mL $84
(S)-(+)-2-Amino-1-butanol ≥98%(Assaybytitration,GC) 39485 1ML $42.46
More product size

(S)-(+)-2-Amino-1-butanol Properties

Melting point -2 °C(lit.)
alpha [α]D20 +9~+11° (neat)
Boiling point 179-183 °C(lit.)
Density 0.944 g/mL at 25 °C(lit.)
refractive index n20/D 1.4521(lit.)
Flash point 184 °F
storage temp. 2-8°C(protect from light)
solubility Soluble in water
pka pK1: 9.52(+1) (25°C)
form clear liquid
color Clear colorless to slightly yellowish viscous liquid
optical activity [α]20/D +10°, neat
Water Solubility 1000g/L at 25℃
Sensitive Air Sensitive & Hygroscopic
BRN 1718930
InChI 1S/C4H11NO/c1-2-4(5)3-6/h4,6H,2-3,5H2,1H3/t4-/m0/s1
InChIKey JCBPETKZIGVZRE-BYPYZUCNSA-N
SMILES CC[C@H](N)CO
CAS DataBase Reference 5856-62-2(CAS DataBase Reference)
FDA UNII 98JEM4YEBR
UNSPSC Code 12352116
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS05
Signal word  Danger
Hazard statements  H314
Precautionary statements  P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338
PPE Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Hazard Codes  C
Risk Statements  34-37-22
Safety Statements  26-36/37/39-45
RIDADR  UN 2735 8/PG 3
WGK Germany  3
RTECS  EK9625000
HazardClass  8
PackingGroup  III
HS Code  29221990
Storage Class 8A - Combustible corrosive hazardous materials
Hazard Classifications Skin Corr. 1B
REACH Registrations Inactive
NFPA 704
2
2 0

(S)-(+)-2-Amino-1-butanol price More Price(37)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 132527 (S)-(+)-2-Amino-1-butanol ≥98% 5856-62-2 5g $123 2026-04-30 Buy
Sigma-Aldrich 132527 (S)-(+)-2-Amino-1-butanol ≥98% 5856-62-2 1g $58.6 2023-06-20 Buy
TCI Chemical A0973 (S)-(+)-2-Amino-1-butanol >98.0%(GC)(T) 5856-62-2 1mL $33 2026-04-30 Buy
TCI Chemical A0973 (S)-(+)-2-Amino-1-butanol >98.0%(GC)(T) 5856-62-2 5mL $84 2026-04-30 Buy
Chem-Impex 39485 (S)-(+)-2-Amino-1-butanol ≥98%(Assaybytitration,GC) 5856-62-2 1ML $42.46 2026-05-19 Buy
Product number Packaging Price Buy
132527 5g $123 Buy
132527 1g $58.6 Buy
A0973 1mL $33 Buy
A0973 5mL $84 Buy
39485 1ML $42.46 Buy

(S)-(+)-2-Amino-1-butanol Chemical Properties,Uses,Production

Chemical Properties

clear colorless to slightly yellowish viscous

Uses

(S)-(+)-2-Amino-1-butanol is a chiral amino alcohol that may be used in the synthesis of (S)-2-(6-benzylamino-9-isopropyl-9H-purin-2-ylamino) butan-1-ol, an (S)-enantiomer of roscovitine. It can also be used to synthesize homochiral 2-methylpyrroles. (S)-(+)-2-Amino-1-butanol is an intermediate for the synthesis of (S,S)-ethambutol, an antibacterial agent for treating tuberculosis.

Synthesis

To a 100 mL round-bottomed flask, aBH4 (0.2 g, 5 mmol) and THF (10 mL) were added. The suspension was stirred and the flask was immersed in an ice-water bath, and an ether solution of L--amino acids (1 mmol) and concentrated H2SO4 (0.132 mL) was added to the reaction flask (0.4 mL in total) to maintain the reaction mixture at a rate of less than 20C. The reaction was carried out in the same manner as the reaction. The reaction mixture was added dropwise at a rate that kept the reaction mixture below 20C. The reaction mixture was stirred at room temperature for 6 h. Methanol (0.4 mL) was carefully added to destroy the excess borane and the reaction was neutralized with 2 M NaOH. The reaction was extracted with 4 x 50 mL of CH2Cl2. The organic extract was dried with magnesium sulfate. The reaction was concentrated to give (S)-(+)-2-amino-1-butanol.

Purification Methods

They are purified by shaking with solid NaOH, filtering and distilling through a short column. The oxalate of the racemate has m 176o. They are strong bases and should be stored under N2 in the absence of CO2. The enantiomers have [] 20 ±12.5o (c 2, EtOH). [Johnson & Degering J Org Chem 8 7 1943, Nagao et al. J Org Chem 51 2392 1986, Santaniello et al. J Chem Soc, Perkin Trans 1 919 1985, Beilstein 4 H 291, 4 IV 1705.]

(S)-(+)-2-Amino-1-butanol Preparation Products And Raw materials

Global( 352)Suppliers
Supplier Tel Email Country ProdList Advantage
Allfluoro pharmaceutical co. ltd.
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+8618957127338 stella@zetchem.com China 2994 58
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View Lastest Price from (S)-(+)-2-Amino-1-butanol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(S)-(+)-2-Amino-1-butanol pictures 2025-05-26 (S)-(+)-2-Amino-1-butanol
5856-62-2
US $10.00 / KG 1KG 99.% 10 ton Hebei Chuanghai Biotechnology Co,.LTD
2-AMINO-1-BUTANOL pictures 2021-07-10 2-AMINO-1-BUTANOL
5856-62-2
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
(S)-(+)-2-Amino-1-butanol >=98% pictures 2021-07-02 (S)-(+)-2-Amino-1-butanol >=98%
5856-62-2
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
  • 2-AMINO-1-BUTANOL pictures
  • 2-AMINO-1-BUTANOL
    5856-62-2
  • US $15.00-10.00 / KG
  • 99%+ HPLC
  • Zhuozhou Wenxi import and Export Co., Ltd
LABOTEST-BB LT01409643 D(+)-2-AMINO-1-BUTANOL D-2-AMINO-1-BUTANOL (+/-)-2-AMINO-1-BUTANOL (S)-(+)-2-AMINO-1-BUTANOL (S)(+)-2-AMINOBUTANOL (S)-2-AMINOBUTANOL (S)-(+)-2-AMINO-1-BUTANOL, 98+% (S)-(+)-2-Amino-1-butanol, ca 95% ee, 98+% 1-Butanol, 2-amino-, (2S)- L-2-Aminobutanol (S)-(+)-2-Amino-1-butanol, 98+% ,ee:95% (S)-(+)-2-Amino-1-butanol, ca 95% ee (2S)-2-Amino-1-butanol (S)-2-Amino-3-methyl-1-propanol (S)-(+)-2-Amino-1-butanol,98+%,ca 95% ee (2S)-(+)-2-Aminobutan-1-ol (S)-(+)-2-AMINO-1-BUTANOL FOR SYNTHESIS (2S)-(+)-1-Hydroxybutan-2-amine, (2S)-(+)-2-Amino-1-hydroxybutane (S)-(+)-2-AMino-1-butanol, 98+% (96% EE/GLC) (S)-(+)-2-Amino-1-butanol, 98%, ee: 95% tube1179 (S)-(+)-2-Amino-1-butanol > 2-AMINO-1-BUTANOL USP/EP/BP (S)-(+)-2-AMINO-1-BUTANOL Extra Pure (+)-2-Amino-1-butanol D-amino-2-butanol S(+)-2-Amino-1-Butanol 98% Extrapure (S)-(+)-2-Amino-1-butanol 2-AMINO-1-BUTANOL (S)-2-AMinobutan-1-ol 5856-62-2 Chiral Building Blocks Amino Alcohols (Chiral) Organic Building Blocks Oxygen Compounds Asymmetric Synthesis Amino Alcohols Building Blocks Amino Alcohols Chiral Building Blocks Organic Building Blocks Amino Alcohols (Chiral) Chiral Building Blocks Synthetic Organic Chemistry Pharmaceutical Intermediates