Chlorflavonin
- CAS No.
- 23363-64-6
- Chemical Name:
- Chlorflavonin
- Synonyms
- Chlorflavonin;Chlorflavonin >=98% (HPLC);3'-Chloro-2',5-dihydroxy-3,7,8-trimethoxyflavone;2-(3-Chloro-2-hydroxyphenyl)-5-hydroxy-3,7,8-trimethoxy-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 2-(3-chloro-2-hydroxyphenyl)-5-hydroxy-3,7,8-trimethoxy-
- CBNumber:
- CB71120160
- Molecular Formula:
- C18H15ClO7
- Molecular Weight:
- 378.76
- MDL Number:
- MFCD32174337
- MOL File:
- 23363-64-6.mol
- MSDS File:
- SDS
| Boiling point | 612.7±55.0 °C(Predicted) |
|---|---|
| Density | 1.52±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO: 2mg/mL, clear |
| pka | 6.61±0.40(Predicted) |
| form | powder |
| color | white to beige |
| InChI | 1S/C18H15ClO7/c1-23-11-7-10(20)12-14(22)18(25-3)15(26-17(12)16(11)24-2)8-5-4-6-9(19)13(8)21/h4-7,20-21H,1-3H3 |
| InChIKey | JLSQXYITDXJTKL-UHFFFAOYSA-N |
| SMILES | OC1=CC(OC)=C(C2=C1C(C(OC)=C(C3=C(O)C(Cl)=CC=C3)O2)=O)OC |
| UNSPSC Code | 51111800 |
| NACRES | NA.21 |
Chlorflavonin price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-1233695 | Chlorflavonin | 23363-64-6 | 1mg | $94 | 2026-06-04 | Buy |
| ChemScene | CS-1233695 | Chlorflavonin | 23363-64-6 | 5mg | $283 | 2026-06-04 | Buy |
| ChemScene | CS-1233695 | Chlorflavonin | 23363-64-6 | 10mg | $452 | 2026-06-04 | Buy |
| ChemScene | CS-1233695 | Chlorflavonin | 23363-64-6 | 25mg | $903 | 2026-06-04 | Buy |
| aablocks | AA00BNRQ | 2-(3-chloro-2-hydroxyphenyl)-5-hydroxy-3,7,8-trimethoxy-4H-chromen-4-one 95.00% | 23363-64-6 | 50mg | $959 | 2026-05-28 | Buy |
Chlorflavonin Chemical Properties, Uses, Production
Definition
ChEBI: A dihydroxyflavone that is flavone substituted by a chloro group at position 3', hydroxy groups at positions 5 and 2' and methoxy groups at positions 3, 7 band 8 respectively.
Biological Activity
Originally isolated from Aspergillus candidus Link, Chlorflavonin is a non-cytotoxic (up to 100 μM; MRC-5 and THP-1) antibiotic with antifungal activity against certain species of mold fungi (MIC = 0.08 μg/mL against A. amstelodami, A. fumigalus, A. ochraceous; Paecilomyces variotii MIC = 2.5 μg/mL, Botrytis cinerea MIC = 5 μg/mL). Chlorflavonin also exhibits antibiotic activity against M. tuberculosis (MIC90 = 1.56 μM) by targeting acetohydroxyacid synthase (AHAS) catalytic subunit ilvB1. Chlorflavonin is superior to streptomycin against M. tuberculosis inside infected macrophages, synergizes with isoniazid and delamanid, leading to a complete sterilization in liquid cultures.
Chlorflavonin Preparation Products And Raw materials
Raw materials
Preparation Products
Chlorflavonin Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zhejiang Huida Biotech Co., LTD | 0571-89903022 18679456698 | zilong@hizyme.com | China | 8001 | 58 |
| Energy Chemical | 400-0056266 | marketing1@energy-chemical.com | China | 44927 | 58 |
| Huai Hua Binfengchem Co., Ltd | 0745-2866851 17711757908 | 3907837691@qq.com | China | 4744 | 58 |
| TargetMol | 400-821-0310 15002144251 | xuexiang.shao@tsbiochem.com | China | 29128 | 58 |
| Supplier | Advantage |
|---|---|
| Zhejiang Huida Biotech Co., LTD | 58 |
| Energy Chemical | 58 |
| Huai Hua Binfengchem Co., Ltd | 58 |
| TargetMol | 58 |
