5-Aminotetrazole
- CAS No.
- 4418-61-5
- Chemical Name:
- 5-Aminotetrazole
- Synonyms
- 1H-TETRAZOL-5-AMINE;5-AMINO-1H-TETRAZOLE;aminotetrazole;5-ATZ;2H-tetrazol-5-amine;5-Amino-1,2,3,4-tetrazole;AURORA KA-6577;-Tetrazolamine;5-Aminoterazole;5 minotetrazole
- CBNumber:
- CB7112166
- Molecular Formula:
- CH3N5
- Molecular Weight:
- 85.07
- MDL Number:
- MFCD00005248
- MOL File:
- 4418-61-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 5-Amino-1H-tetrazole >98.0%(HPLC)(T) | A0427 | 25g | $60 |
| 5-Amino-1H-tetrazole >98.0%(HPLC)(T) | A0427 | 100g | $150 |
| 5-Aminotetrazole 99+% ≥99% | 233897 | 1g | $156 |
| 5-Amino-1H-tetrazole | FA46406 | 0.05kg | $150 |
| 5-Amino-1H-tetrazole | FA46406 | 0.025kg | $150 |
| More product size | |||
| Melting point | 201-205 °C(lit.) |
|---|---|
| Boiling point | 57.6°C (rough estimate) |
| Density | 1.50 g/cm3 |
| vapor pressure | 0Pa at 25℃ |
| refractive index | 2.1050 (estimate) |
| pka | pK1: 1.76;pK2: 6.07 (20°C) |
| form | powder to crystal |
| color | White to Almost white |
| Water Solubility | 12g/L(18 ºC) |
| InChI | InChI=1S/CH3N5/c2-1-3-5-6-4-1/h(H3,2,3,4,5,6) |
| InChIKey | ULRPISSMEBPJLN-UHFFFAOYSA-N |
| SMILES | N1=C(N)N=NN1 |
| LogP | -0.92 at 23℃ |
| CAS DataBase Reference | 4418-61-5(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 28JR5LD42T |
| NIST Chemistry Reference | 1H-Tetrazol-5-amine(4418-61-5) |
| EPA Substance Registry System | 1H-Tetrazol-5-amine (4418-61-5) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H228-H302+H312+H332 | |||||||||
| Precautionary statements | P210-P240-P241-P261-P264-P270-P271-P280-P301+P312+P330-P302+P352+P312+P362+P364-P304+P340+P312-P501 | |||||||||
| Hazard Codes | Xn,F,Xi | |||||||||
| Risk Statements | 22-36/37/38-20/21/22-11 | |||||||||
| Safety Statements | 26-36/37-36-16-7/9 | |||||||||
| RIDADR | 1325 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | XF7465000 | |||||||||
| Hazard Note | Flammable/Irritant | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 4.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29339900 | |||||||||
| REACH Registrations | Active | |||||||||
| Limited Quantities | 5.0 Kg (11 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) | |||||||||
| NFPA 704 |
|
5-Aminotetrazole price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | A0427 | 5-Amino-1H-tetrazole >98.0%(HPLC)(T) | 4418-61-5 | 25g | $60 | 2026-04-30 | Buy |
| TCI Chemical | A0427 | 5-Amino-1H-tetrazole >98.0%(HPLC)(T) | 4418-61-5 | 100g | $150 | 2026-04-30 | Buy |
| Usbiological | 233897 | 5-Aminotetrazole 99+% ≥99% | 4418-61-5 | 1g | $156 | 2026-06-03 | Buy |
| Biosynth | FA46406 | 5-Amino-1H-tetrazole | 4418-61-5 | 0.05kg | $150 | 2026-06-04 | Buy |
| Biosynth | FA46406 | 5-Amino-1H-tetrazole | 4418-61-5 | 0.025kg | $150 | 2026-06-04 | Buy |
5-Aminotetrazole Chemical Properties,Uses,Production
Chemical Properties
White Crystalline powder
Uses
organic intermediate
Uses
5-Aminotetrazole (5-AT) is an important class of nitrogen-containing heterocyclic compounds and serves as a widely used and highly efficient synthetic unit or building block. 5-AT exhibits a variety of biological activities (such as antiviral, antitumour, antibacterial and antihistamine activities). Furthermore, this structure forms the core skeleton of many known drugs (such as glutamate receptor modulators and HIF-2 inhibitors, etc.) (see figure below) [1]. In addition, it has extensive applications in coordination chemistry and materials science (including explosives and photographic materials). As a high-nitrogen-energy ligand, 5-AT can be used in the preparation of novel metal-organic frameworks (MOFs) [2].
Application
5-Aminotetrazole can be used as a propellant in pyrotechnic products, such as gas generators, airbags and smoke signal devices. Owing to its high nitrogen content (82 per cent) and high heat of combustion (208 kJ·mol⁻¹), it is often mixed with an oxidiser in practical applications.
Hazard
Moderately toxic. An unstable material; explodes with KOH.
Flammability and Explosibility
Not classified
Synthesis
5-Aminotetrazole (5-AT) is synthesized by reacting cyanamide or dicyandiamide with an azide salt at high temperature in the presence of an acidic reagent (such as boric acid). The pKa value of this acidic reagent is between 3 and 7. The reaction solution is heated to above 75°C, preferably at reflux temperature (usually above 90°C). No large amounts of azide acid are generated during the reaction. After the reaction is complete, a strong acid (such as hydrochloric acid) is added to the reaction solution to acidify it, lowering the pH to below 3, causing the generated 5-AT to be protonated and precipitated. Finally, the pure 5-AT product is separated by conventional methods such as filtration and washing. The synthetic route is shown below:
References
[1] de Jesus, I. S., Gomes, A. T., Sande, I., & Cunha, S. (2024). Three-Component Synthesis of 1-Substituted 5-Aminotetrazoles Promoted by Bismuth Nitrate. The Journal of Organic Chemistry, 63 1. https://doi.org/10.1021/acs.joc.4c01727
[2] Yanzhao Hao . (2024). Construction of energetic metal-organic frameworks based on 5-aminotetrazole. Inorganic Chemistry Communications, 164, Article 112354. https://doi.org/10.1016/j.inoche.2024.112354
5-Aminotetrazole Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BorayChem (Shanghai) New Materials Co., Ltd. | +86-13918125044 +86-13918125044 | moon.zhang@boray-chem.com | China | 4 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
| SHANGHAI YOUNG-CHEM CHEMICAL CO., LTD. | +8613817489192 | hebe@ychemchemical.com | China | 2435 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 | sales1@chuanghaibio.com | China | 5225 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 | deasea125996@gmail.com | China | 2472 | 58 |
| Hebei Longbang Technology Co., LTD | +86-18633929156 | admin@hblongbang.com | China | 972 | 58 |
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 | niki@zlchemi.com | China | 7245 | 58 |
| Wuhan JiyunZen Tech Co., Ltd. | +86-18062099985 | Amyjiyunzen@yeah.net | China | 672 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
Related articles
- In vitro and in vivo effects of 5-aminotetrazole and 5-Aminotetrazole-Based Energetic Polymers
- Commercially, 5-aminotetrazole (5-AT) is used in gas generator formulations for airbags, fireworks, and roadside flares.
- Apr 22，2025
View Lastest Price from 5-Aminotetrazole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-05-28 | 5-Aminotetrazole
4418-61-5
|
$10.00 | 1KG | 99% | 10 ton | Hebei Chuanghai Biotechnology Co,.LTD | |
 |
2026-04-10 | 5-Aminotetrazole
4418-61-5
|
$2.00-5.00 | 1KG | 99% hplc | 500TONS | Wuhan JiyunZen Tech Co., Ltd. | |
 |
2026-03-20 | 5-Aminotetrazole
4418-61-5
|
$1.00 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd |
-
- 5-Aminotetrazole
4418-61-5
- $10.00
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
-
- 5-Aminotetrazole
4418-61-5
- $2.00-5.00
- 99% hplc
- Wuhan JiyunZen Tech Co., Ltd.
-
- 5-Aminotetrazole
4418-61-5
- $1.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
