ChemicalBook >> CAS DataBase List >>Sclareolide
Sclareolide
- CAS No.
- 564-20-5
- Chemical Name:
- Sclareolide
- Synonyms
- Clareolide;Norambreinolide;(+)-Sclareolide;FEMA 3794;(3AR)-(+)-SCLAREOLIDE;(3aR,5aS,9aS,9bR)-Decahydro-3a,6,6,9a-tetramethylnaphtho[2,1-b]furan-2(1H)-one;Naphtho[2,1-b]furan-2(1H)-one, decahydro-3a,6,6,9a-tetramethyl-, (3aR,5aS,9aS,9bR)-;1-b]furan-2(1H)-one,decahydro-3a,6,6,9a-tetramethyl-,[3aR-(3a.alpha.,5a.beta.,9a.alpha.,9b.beta.)Naphtho[2;SCLAREOLIDE;SCLAREOLIDE(P)
- CBNumber:
- CB7114584
- Molecular Formula:
- C16H26O2
- Molecular Weight:
- 250.38
- MDL Number:
- MFCD00134168
- MOL File:
- 564-20-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-07-16 07:06:08
| Melting point | 124-126 °C (lit.) |
|---|---|
| alpha | 47 º(c=2, chloroform) |
| Boiling point | 321.4±10.0 °C(Predicted) |
| Density | 1.009±0.06 g/cm3(Predicted) |
| vapor pressure | 0Pa at 25℃ |
| FEMA | 3794 | SCLAREOLIDE |
| FLAVIS Number | 16.055 | (R)-(+)-Sclareolide |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), DMSO (Slightly) |
| form | Solid |
| color | White to Off-White |
| Odor | at 10.00 % in isopropyl myristate. dry paper woody ambergris labdanum |
| Odor Type | woody |
| biological source | Salvia sclarea L |
| optical activity | [α]20/D +47°, c = 2% in chloroform |
| Water Solubility | 10mg/L at 25℃ |
| JECFA Number | 1165 |
| Major Application | flavors and fragrances |
| Cosmetics Ingredients Functions |
FRAGRANCE SKIN CONDITIONING PERFUMING |
| InChI | 1S/C16H26O2/c1-14(2)7-5-8-15(3)11(14)6-9-16(4)12(15)10-13(17)18-16/h11-12H,5-10H2,1-4H3/t11-,12+,15-,16+/m0/s1 |
| InChIKey | IMKJGXCIJJXALX-SHUKQUCYSA-N |
| SMILES | [H][C@@]12CC[C@@]3(C)OC(=O)C[C@]3([H])[C@@]1(C)CCCC2(C)C |
| LogP | 4.5 at 25℃ |
| Substances Added to Food (formerly EAFUS) | SCLAREOLIDE |
| EWG's Food Scores | 1 |
| FDA UNII | 37W4O0O6E6 |
| NIST Chemistry Reference | Naphtho[2,1-b]furan-2(1h)-one, decahydro-3a,6,6,9a-tetramethyl-, [3ar-(3a«alpha»,5a«beta»,9a«alpha»,9b«beta»)]-(564-20-5) |
| EPA Substance Registry System | Naphtho[2,1-b]furan-2(1H)-one, decahydro-3a,6,6,9a-tetramethyl-, (3aR,5aS,9aS,9bR)- (564-20-5) |
| UNSPSC Code | 12352005 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H411 |
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P |
| PPE | Eyeshields, Gloves, type N95 (US) |
| Safety Statements | 24/25 |
| WGK Germany | 2 |
| TSCA | TSCA listed |
| HS Code | 29322090 |
| Storage Class | 11 - Combustible Solids |
| REACH Registrations | Active |
Sclareolide price More Price(61)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | W379401 | (3aR)-(+)-Sclareolide natural, 97%, FG | 564-20-5 | 1 each | $61.1 | 2026-04-30 | Buy |
| Sigma-Aldrich | 358002 | (3aR)-(+)-Sclareolide 97% | 564-20-5 | 5g | $86.7 | 2026-04-30 | Buy |
| Sigma-Aldrich | W379401 | (3aR)-(+)-Sclareolide natural, 97%, FG | 564-20-5 | 1 unit | $56.62 | 2025-07-31 | Buy |
| TCI Chemical | S0847 | (3aR)-(+)-Sclareolide >97.0%(GC) | 564-20-5 | 5g | $47 | 2026-04-30 | Buy |
| TCI Chemical | S0847 | (3aR)-(+)-Sclareolide >97.0%(GC) | 564-20-5 | 25g | $132 | 2026-04-30 | Buy |
Sclareolide Chemical Properties,Uses,Production
Chemical Properties
Sclareolide has a musky, wood odor.
Occurrence
Reported present in clary sage bush (Salvia sclarea)
Uses
Sclareolide is found in Salvia yosgadensis and is a close analog of sclareol, an antifungal diterpene.
Uses
antimicrobial
Uses
sclareolide is a fragrancing ingredient, it can help mask formulation odors. It is synthetically manufactured.
Preparation
Sclareol, isolated from clary sage by solvent extraction, can be efficiently oxidized by the microorganism Cryptococcus albidus to sclareolide.
Definition
ChEBI: Norambreinolide is a naphthofuran.
General Description
Sclareolide is a diterpenoid compound mainly used in the perfume industry for its amber like odor.
Flammability and Explosibility
Not classified
Sclareolide Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 496)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan Wsem Biological Co., Ltd. | 027-83778876; 13667159345 | 13667159345@163.com | China | 1908 | 55 |
| Shaanxi Pioneer Biotech Co., Ltd. | 13720616393；029-84385017-8003 13720616393 | sales@pioneerbiotech.com | China | 776 | 56 |
| Xi'an Kono chem co., Ltd., | 029-029-86107037-8012-8012 18729555803 | sales9@konochemical.com | China | 259 | 58 |
| Suzhou Sanyi Polymer Chemical Technology Co., Ltd. | 13951113810 | 170354953@qq.com | China | 127 | 58 |
| Chongqing Richem Biotechnology Co., Ltd. | 023-63989584 13983114937 | yuanhong.qi@cqrichem.cn | China | 45 | 58 |
| Nanjing bingcheng Biotechnology Co., Ltd. | 18805194892 | 2727751293@qq.com | China | 172 | 58 |
| Shanghai Boyle Chemical Co., Ltd. | 021-50182298 021-50180596 | sales@boylechem.com | China | 2202 | 55 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
Related articles
- What is Sclareolide used for?
- Sclareolide has various biological activities, such as antifungal, antibacterial, anticancer, anti-inflammatory, and cytotoxic....
- Dec 21,2023
View Lastest Price from Sclareolide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-25 | Sclareolide
564-20-5
|
1KG | 0.99 | 1000KG | Shaanxi Xianhe Biotech Co., Ltd | ||
 |
2026-08-09 | (3aR)-(+)-Sclareolide
564-20-5
|
99% | 2000kgs | Chongqing Zhihe Biopharmaceutical Co., Ltd. | |||
 |
2026-08-03 | Sclareolide
564-20-5
|
$1.00 | 1kg | 99 | 100 | Henan Boweixin Biotechnology Co., Ltd. |
-
- Sclareolide
564-20-5
- $0.00
- 0.99
- Shaanxi Xianhe Biotech Co., Ltd
-
- (3aR)-(+)-Sclareolide
564-20-5
- 99%
- Chongqing Zhihe Biopharmaceutical Co., Ltd.
-
- Sclareolide
564-20-5
- $1.00
- 99
- Henan Boweixin Biotechnology Co., Ltd.
564-20-5(Sclareolide)Related Search:
SCLAREOLIDE
1-b]furan-2(1H)-one,decahydro-3a,6,6,9a-tetramethyl-,[3aR-(3a.alpha.,5a.beta.,9a.alpha.,9b.beta.)Naphtho[2
Naphtho[2,1-b]furan-2(1H)-one,decahydro-3a,6,6,9a-
tetramethyl-,(3aR,5aS,9aS,9bR)-
Sclareolide (Dodecahydro-3a,6,6,9a,-tetramethylnaphto(2,1-b Furan–2–one)
Sclareolide (Dodecahydro-3a,6,6,9a,-tetramethylnaphto(2,1-b Furanne)
Sclareolide (3aR)-(+)-Sclareolide
(3aR)-(+)-Sclareolide 97%
Naphtho[2,1-b]furan-2(1H)-one, decahydro-3a,6,6,9a-tetramethyl-, (3aR,5aS,9aS,9bR)-
Sclareolide (NoraMbreinolide)
Sclareolide 564-20-5
[3aR-(3aalpha,5abeta,9aalpha,9bbeta)]Decahydro-3a,6,6,9a-tetramethylnaphth[2,1-b]furan-2(1H)-one
1-b]furan-2(1h)-one,decahydro-3a,6,6,9a-tetramethyl-naphtho[[3atheta-(3a
5abeta,9aalpha,9bbeta)]-alph
Decahydro-3a,6,6,9a-tetramethylnaphtho[2,1-b]furan-2(1H)-one
Norambrienolide
decahydro tetramentyl naphtho-furanone
Clary sage lactone
SCLAREOLIDE(P)
SCLAREOLIDE(SH)
(3aR-(3aalpha,5abeta,9aalpha,9bbeta))Decahydro-3a,6,6,9a-tetramethylnaphth(2,1-b)furan-2(1H)-on
SCLAREOLIDE IN TOLUENE
SLAREOLIDE, NATURAL
(3aR)-(+)-Sclareolide >
(3aR,5aS,9aS,9bR)-3a,6,6,9a-Tetramethyldecahydronaphtho[2,1-b]furan-2(3aH)-one
Sclareolide USP/EP/BP
Nano-Liposomal SCLAREOLIDE
Water-Soluble SCLAREOLIDE
Fragrant Perilla Lactone
[3aR-(3aα,5aβ,9aα,9bβ)]decahydro-3a,6,6,9a-tetramethylnaphth[2,1-b]furan-2(1H)-one
(3aR)-(+)-Sclareolide
Semi-Volatiles Mix, 18-3691, 1000 mg/L
(+)-Sclareolide
(3aR,5aS,9aS,9bR)-Decahydro-3a,6,6,9a-tetramethylnaphtho[2,1-b]furan-2(1H)-one
(3AR)-(+)-SCLAREOLIDE
Clareolide
FEMA 3794
Norambreinolide
(3aR,5aS,9aS,9bR)-3a,6,6,9a-tetramethyl-1,4,5,5a,7,8,9,9b-octahydrobenzo[e][1]benzofuran-2-one
564-20-5
534-20-5
C16H26O2
Chiral Building Blocks
Asymmetric Synthesis
Furans
Heterocyclic Building Blocks
Miscellaneous Natural Products
Natural Plant Extract
Flavors and Fragrances
Inhibitors
Flavors & Fragrances
Chiral Building Blocks
Furans
Heterocyclic Building Blocks
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