Levofloxacin-d8 (hydrochloride)
- CAS No.
- 2699607-50-4
- Chemical Name:
- Levofloxacin-d8 (hydrochloride)
- Synonyms
- (2S)-7-fluoro-2-methyl-6-(2,2,3,3,5,5,6,6-octadeuterio-4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid
- CBNumber:
- CB712129497
- Molecular Formula:
- C18H12D8FN3O4.ClH
- Molecular Weight:
- 405.88
- MDL Number:
- MOL File:
- 2699607-50-4.mol
- MSDS File:
- SDS
Levofloxacin-d8 (hydrochloride) price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 29080 | Levofloxacin-d8 (hydrochloride) ≥99%deuteratedforms(d1-d8) | 2699607-50-4 | 1mg | $499 | 2026-04-30 | Buy |
| Cayman Chemical | 29080 | Levofloxacin-d8 (hydrochloride) ≥99% deuterated forms (d1-d8) | 2699607-50-4 | 1 mg | $251 | 2024-03-01 | Buy |
| ChemScene | CS-0377665 | Levofloxacin-d8 (hydrochloride) 99.0% | 2699607-50-4 | 1mg | $607 | 2026-06-04 | Buy |
| aablocks | AA01XHK8 | Levofloxacin-d8 (hydrochloride) ≥99%deuteratedforms(d1-d8) | 2699607-50-4 | 1mg | $499 | 2026-06-01 | Buy |
Levofloxacin-d8 (hydrochloride) Chemical Properties, Uses, Production
Description
Levofloxacin-d8 is intended for use as an internal standard for the quantification of levofloxacin by GC- or LC-MS. Levofloxacin is a fluoroquinolone antibiotic and the active stereoisomer of ofloxacin .1 It is active against S. aureus, S. epidermidis, B. subtilis, E. coli, P. aeruginosa, and K. pneumoniae (MICs = 0.25, 0.25, 0.5, 0.03, 4, and 0.25 μg/ml, respectively).2 Levofloxacin inhibits S. aureus DNA gyrase and topoisomerase IV (IC50s = 8.06 and 9.81 μg/ml, respectively).3 It eliminates infection in rat models of endocarditis caused by methicillin-sensitive or -resistant S. aureus.4 Formulations containing levofloxacin have been used in the treatment of various bacterial infections.
Uses
Levofloxacin-d8 (hydrochloride) is deuterium labeled Levofloxacin (hydrochloride).
References
1. Norrby, S.R. Levofloxacin Expert Opin. Pharmacother. 1(1),109-119(1999).
2. Mohammadhosseini, N., Alipanahi, Z., Alipour, E., et al. Synthesis and antibacterial activity of novel levofloxacin derivatives containing a substituted thienylethyl moiety. Daru. 20(1),(2012).
3. Takei, M., Fukuda, H., Kishii, R., et al. Target preference of 15 quinolones against Staphylococcus aureus, based on antibacterial activities and target inhibition Antimicrob. Agents Chemother. 45(12),3544-3547(2001).
4. Entenza, J.M., Vouillamoz, J., Glauser, M.P., et al. Levofloxacin versus ciprofloxacin, flucloxacillin, or vancomycin for treatment of experimental endocarditis due to methicillin-
Levofloxacin-d8 (hydrochloride) Preparation Products And Raw materials
Raw materials
Preparation Products
Levofloxacin-d8 (hydrochloride) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| CHINA ISOTOPE CO., LIMITED | 02151600108 13062666369 | info@isotopechem.com | China | 4721 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 17301488900 | judy.xia@synzest.com | China | 12577 | 58 |
| TLC Pharmaceutical Standards Ltd. | 18012923235 | chinasales04@tlcstandards.com.cn | China | 8143 | 58 |
| Zhejiang Huida Biotech Co., Ltd. | 0571-89903022 18679456698 | zilong@hizyme.com | China | 7853 | 58 |
