2-Amino-4-chloromethythiazole hydrochloride
- CAS No.
- 59608-97-8
- Chemical Name:
- 2-Amino-4-chloromethythiazole hydrochloride
- Synonyms
- 2-thiazolamine, 4-(chloromethyl)-;2-AMino-4-chloroMethythiazole, HCl;2-AMINO-4-(CHLOROMETHYL)THIAZOLE HCI;2-AMINO-4-(CHLOROMETHYL)THIAZOLE HCL;2-AMINO-4-CHLOROMETHYTHIAZOLE HYDROCHLORIDE;4-CHLOROMETHYL-THIAZOL-2-YLAMINE HYDROCHLORIDE;2-AMINO-4-(CHLOROMETHYL)THIAZOLE HYDROCHLORIDE;2-ThiazolaMine,4-(chloroMethyl)-, hydrochloride;4-(chloromethyl)-1,3-thiazol-2-amine hydrochloride;2-Amino-4-(chloromethyl)-1,3-thiazole hydrochloride
- CBNumber:
- CB7123742
- Molecular Formula:
- C4H6Cl2N2S
- Molecular Weight:
- 185.07
- MDL Number:
- MFCD00035215
- MOL File:
- 59608-97-8.mol
| Melting point | 141-143 °C(Solv: ethanol (64-17-5)) |
|---|---|
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | solid |
| Appearance | White to off-white Solid |
| CAS DataBase Reference | 59608-97-8(CAS DataBase Reference) |
| EPA Substance Registry System | 2-Thiazolamine, 4-(chloromethyl)-, monohydrochloride (59608-97-8) |
| UNSPSC Code | 12352200 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H317-H319 |
| Precautionary statements | P280-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 43 |
| Safety Statements | 36/37 |
| HazardClass | IRRITANT |
| HS Code | 2934100090 |
2-Amino-4-chloromethythiazole hydrochloride price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SYX00295 | 2-Amino-4-(chloromethyl)thiazole hydrochloride | 59608-97-8 | 1g | $107 | 2025-07-31 | Buy |
| TRC | C587905 | 4-(Chloromethyl)thiazol-2-amineHydrochloride | 59608-97-8 | 500mg | $75 | 2021-12-16 | Buy |
| Matrix Scientific | 012092 | 4-Chloromethyl-thiazol-2-ylaminehydrochloride | 59608-97-8 | 5g | $94 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | COR0001610 | 2-AMINO-4-CHLOROMETHYTHIAZOLE HYDROCHLORIDE 95.00% | 59608-97-8 | 2.5G | $1091.99 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | COR0001610 | 2-AMINO-4-CHLOROMETHYTHIAZOLE HYDROCHLORIDE 95.00% | 59608-97-8 | 5G | $1819.13 | 2021-12-16 | Buy |
2-Amino-4-chloromethythiazole hydrochloride Chemical Properties,Uses,Production
Uses
2-Amino-4-chloromethyl thiazole hydrochloride is an α-thiophene derivative, which is widely used in synthetic medicines, pesticides, dyes, chemical reagents, polymer additives, etc.
Synthesis
17356-08-0
534-07-6
59608-97-8
The general procedure for the synthesis of 2-amino-4-chloromethylthiazole hydrochloride from the compound (CAS: 17356-08-0) and 1,3-dichloroacetone was carried out as follows: a mixture of 1,3-dichloroacetone (380.9 g, 3 mol), thiourea (228.3 g, 3 mol), and isopropanol (3.6 L) was stirred at 40 °C in an inert atmosphere until a clarified solution. Subsequently, the reaction mixture was continued to be stirred at room temperature overnight to induce crystallization of the product. Upon completion of the reaction, the mixture was cooled to -20 °C to promote complete crystallization and the product was subsequently isolated by filtration. The resulting crystals were washed with cold isopropanol (0.4 L) and finally dried under vacuum to afford 2-amino-4-chloromethylthiazole hydrochloride as white crystals (408 g, 73.5% yield).
References
[1] Journal of Medicinal Chemistry, 2016, vol. 59, # 21, p. 9686 - 9720
[2] Patent: WO2009/15193, 2009, A1. Location in patent: Page/Page column 44
[3] Bollettino Chimico Farmaceutico, 1995, vol. 134, # 11, p. 639 - 643
[4] Patent: WO2008/11191, 2008, A1. Location in patent: Page/Page column 36
[5] Patent: EP3018125, 2016, A1. Location in patent: Paragraph 0753-0755
2-Amino-4-chloromethythiazole hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
2-Amino-4-chloromethythiazole hydrochloride Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | stella@zetchem.com | China | 2136 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49730 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29802 | 58 |
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| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
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| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; | peter68@ptchemgroup.com | China | 35425 | 58 |
| ZHEJIANG JIUZHOU CHEM CO., LTD | +86-0576225566889 +86-13454675544 | admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com | China | 12272 | 58 |
View Lastest Price from 2-Amino-4-chloromethythiazole hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-12-20 | 2-Amino-4-chloromethythiazole hydrochloride
59608-97-8
|
US $1.00 / KG | 1KG | 95%~99% | 1ton | Career Henan Chemical Co |
-
- 2-Amino-4-chloromethythiazole hydrochloride
59608-97-8
- US $1.00 / KG
- 95%~99%
- Career Henan Chemical Co
