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6-Benzothiazolol,2-(methylthio)-(9CI)

CAS No.
74537-49-8
Chemical Name:
6-Benzothiazolol,2-(methylthio)-(9CI)
Synonyms
2-Methylthiobenzothiazol-6-ol;6-Benzothiazolol, 2-(methylthio)-;2-(Methylthio)benzo[d]thiazol-6-ol;6-Benzothiazolol,2-(methylthio)-(9CI);2-(methylsulfanyl)-1,3-benzothiazol-6-ol
CBNumber:
CB71277239
Molecular Formula:
C8H7NOS2
Molecular Weight:
197.28
MDL Number:
MFCD14585416
MOL File:
74537-49-8.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:49
Product description Number Pack Size Price
2-(Methylthio)benzo[d]thiazol-6-ol 132020 250.00mg $36
2-(Methylthio)benzo[d]thiazol-6-ol 132020 1.00g $72
2-(Methylthio)benzo[d]thiazol-6-ol 132020 5.00g $261
2-(Methylthio)benzo[d]thiazol-6-ol 95+% M48559 100mg $80
2-(Methylthio)benzo[d]thiazol-6-ol 95+% M48559 250mg $100

6-Benzothiazolol,2-(methylthio)-(9CI) Properties

Melting point 131-132 °C
Boiling point 375.3±34.0 °C(Predicted)
Density 1.46±0.1 g/cm3(Predicted)
storage temp. 2-8°C
pka 8.43±0.40(Predicted)
InChI InChI=1S/C8H7NOS2/c1-11-8-9-6-3-2-5(10)4-7(6)12-8/h2-4,10H,1H3
InChIKey IAQHORMPRYVLJX-UHFFFAOYSA-N
SMILES S1C2=CC(O)=CC=C2N=C1SC

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319
Precautionary statements  P261-P305+P351+P338

6-Benzothiazolol,2-(methylthio)-(9CI) price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 132020 2-(Methylthio)benzo[d]thiazol-6-ol 74537-49-8 250.00mg $36 2026-05-18 Buy
Matrix Scientific 132020 2-(Methylthio)benzo[d]thiazol-6-ol 74537-49-8 1.00g $72 2026-05-18 Buy
Matrix Scientific 132020 2-(Methylthio)benzo[d]thiazol-6-ol 74537-49-8 5.00g $261 2026-05-18 Buy
Synthonix M48559 2-(Methylthio)benzo[d]thiazol-6-ol 95+% 74537-49-8 100mg $80 2026-05-06 Buy
Synthonix M48559 2-(Methylthio)benzo[d]thiazol-6-ol 95+% 74537-49-8 250mg $100 2026-05-06 Buy
Product number Packaging Price Buy
132020 250.00mg $36 Buy
132020 1.00g $72 Buy
132020 5.00g $261 Buy
M48559 100mg $80 Buy
M48559 250mg $100 Buy

6-Benzothiazolol,2-(methylthio)-(9CI) Chemical Properties,Uses,Production

Synthesis

2(3H)-Benzothiazolethione,6-hydroxy-(9CI)

74537-63-6

Iodomethane

74-88-4

6-Benzothiazolol,2-(methylthio)-(9CI)

74537-49-8

Step 2. Preparation of 2-(methylmercapto)benzo[d]thiazol-6-ol: 2-mercaptobenzo[d]thiazol-6-ol (3.80 g, 20.76 mmol, 1.0 eq.) obtained from Step 1 was dissolved in dichloromethane (40 mL, 0.5 M) and cooled to 0 °C in an ice bath. Under stirring, triethylamine (7.29 mL, 51.91 mmol, 2.5 eq.) and iodomethane (1.93 mL, 31.14 mmol, 1.5 eq.) were added sequentially. The reaction temperature was maintained between 0 °C and -10 °C with continuous stirring for 3 hours. Upon completion of the reaction, the solvent was removed by rotary evaporator under reduced pressure. Water (~200 mL) was added to the residue and the aqueous layer was subsequently extracted with ethyl acetate (3 x 150 mL). The organic layers were combined, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to afford 2-(methylmercapto)benzo[d]thiazol-6-ol (3.76 g, 92% yield) in light green powder form.

References

[1] Patent: US2008/45528, 2008, A1. Location in patent: Page/Page column 47
[2] Australian Journal of Chemistry, 1979, vol. 32, # 12, p. 2713 - 2726

6-Benzothiazolol,2-(methylthio)-(9CI) Preparation Products And Raw materials

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6-Benzothiazolol,2-(methylthio)-(9CI) Spectrum

6-Benzothiazolol,2-(methylthio)-(9CI) 2-(Methylthio)benzo[d]thiazol-6-ol 2-(methylsulfanyl)-1,3-benzothiazol-6-ol 6-Benzothiazolol, 2-(methylthio)- 2-Methylthiobenzothiazol-6-ol 74537-49-8 BENZOTHIAZOLE