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artemisic acid

CAS No.
80286-58-4
Chemical Name:
artemisic acid
Synonyms
Qinghao acid;Qing Hau acid;Artemisia Acid;artemisic acid;Artimisinic Acid;ARTEMISININIC ACID;(+)-artemisinicaci;(+)-Artemisinic Acid;Artemisic acid, 10 mM in DMSO;4,11(13)-Cadinadien-12-oic acid
CBNumber:
CB71371483
Molecular Formula:
C15H22O2
Molecular Weight:
234.33
MDL Number:
MFCD00238540
MOL File:
80286-58-4.mol
MSDS File:
SDS
Last updated:2025-09-25 17:15:13
Product description Number Pack Size Price
Artemisinic Acid ≥98% 25059 10mg $43
Artemisinic Acid ≥98% 25059 25mg $100
Artemisinic Acid ≥98% 25059 50mg $178
Artemisinic Acid ≥98% 25059 100mg $270
Artemisic acid 299948 10mg $490
More product size

artemisic acid Properties

Melting point 129-131℃
Boiling point 373.6±11.0 °C(Predicted)
Density 1.019
storage temp. -20°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), Methanol (Slightly)
pka 4.32±0.11(Predicted)
form Solid
color White to Pale Yellow
InChI InChI=1/C15H22O2/c1-9-4-6-12-10(2)5-7-13(14(12)8-9)11(3)15(16)17/h8,10,12-14H,3-7H2,1-2H3,(H,16,17)/t10-,12+,13+,14+/s3
InChIKey PLQMEXSCSAIXGB-OGGOGTMWNA-N
SMILES [C@]12([H])C=C(CC[C@@]1([H])[C@@H](CC[C@H]2C(=C)C(=O)O)C)C |&1:0,6,8,11,r|
LogP 5.086 (est)
FDA UNII 53N99527G7

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P301+P312-P302+P352-P304+P340-P305+P351+P338

artemisic acid price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 25059 Artemisinic Acid ≥98% 80286-58-4 10mg $43 2024-03-01 Buy
Cayman Chemical 25059 Artemisinic Acid ≥98% 80286-58-4 25mg $100 2024-03-01 Buy
Cayman Chemical 25059 Artemisinic Acid ≥98% 80286-58-4 50mg $178 2024-03-01 Buy
Cayman Chemical 25059 Artemisinic Acid ≥98% 80286-58-4 100mg $270 2024-03-01 Buy
Usbiological 299948 Artemisic acid 80286-58-4 10mg $490 2021-12-16 Buy
Product number Packaging Price Buy
25059 10mg $43 Buy
25059 25mg $100 Buy
25059 50mg $178 Buy
25059 100mg $270 Buy
299948 10mg $490 Buy

artemisic acid Chemical Properties,Uses,Production

Uses

Artemisic Acid is a derivative of Artemisinin (A777500), an antimalarial constituent of the tradional Chinese medicinal herb Artemisia annua L., Compositae, which has been known for almost 2000 years as Qinghao. Antimalarial.

Definition

ChEBI: A monocarboxylic acid that is prop-2-enoic acid which is substituted at position 2 by a 4,7-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalen-1-yl group (the 1S,4R,4aS,8aR diastereoisomer). I is a sesquiterpenoid precursor of artemisinin, obtained from sweet wormwood, Artemisia annua.

Synthesis

Artemisinic Alcohol Impurity

125184-95-4

artemisic acid

80286-58-4

Jones reagent (1.4 M CrO3 in 2.2 M H2SO4 aqueous solution) was added dropwise to a 1 mL acetone solution containing 0.2 mmol of compound 6 (CAS: 125184-95-4) at 0 °C. The reaction mixture was slowly warmed to room temperature and stirred continuously until complete consumption of Feedstock 6 was confirmed by thin layer chromatography (TLC) monitoring. Upon completion of the reaction, water and dichloromethane (CH2Cl2) were added to the mixture for extraction. The organic layer was separated and washed with distilled water and subsequently dried with anhydrous magnesium sulfate (MgSO4). The solvent was evaporated under reduced pressure to afford the target product 2-((1R,4R,4aS,8aR)-4,7-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalen-1-yl)acrylic acid in quantitative yield (confirmed by LC/MS). Compound 2 can be further converted to DHAA (3) according to Roth and Acton in Journal of the Chemical Society, Chemical Communications (1989, 24, 1998) or by catalytic hydrogenation (see Example 4).

References

[1] Patent: US2006/270863, 2006, A1. Location in patent: Page/Page column 19

125184-95-4
80286-58-4
Synthesis of artemisic acid from Artemisinic Alcohol Impurity

artemisic acid Preparation Products And Raw materials

Global( 208)Suppliers
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Hebei Chuanghai Biotechnology Co,.LTD
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18502101150 ft-sales@nature-standard.com CHINA 1923 58

View Lastest Price from artemisic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Artemisic acid pictures 2025-10-17 Artemisic acid
80286-58-4
US $0.00 / mg 20mg 98% HPLC 1000kg Changsha Staherb Natural Ingredients Co., Ltd.
Dihydroartemisinic Artemisic Acid pictures 2025-05-26 Dihydroartemisinic Artemisic Acid
80286-58-4
US $11.00 / kg 1kg 99% 10000kg Hebei Chuanghai Biotechnology Co,.LTD
artemisic acid pictures 2023-07-31 artemisic acid
80286-58-4
US $1.00 / kg 20kg 99% 500tons Hebei Linwo New Material Technology Co., LTD
  • Artemisic acid pictures
  • Artemisic acid
    80286-58-4
  • US $0.00 / mg
  • 98% HPLC
  • Changsha Staherb Natural Ingredients Co., Ltd.
  • artemisic acid pictures
  • artemisic acid
    80286-58-4
  • US $1.00 / kg
  • 99%
  • Hebei Linwo New Material Technology Co., LTD
artemisic acid Artimisinic Acid 2-[[(1R)-4β,7-Dimethyl-1,2,3,4,4aβ,5,6,8aβ-octahydronaphthalen]-1α-yl]acrylic acid Qing Hau acid Qinghao acid 1-Naphthaleneaceticacid, 1,2,3,4,4a,5,6,8a-octahydro-4,7-dimethyl-a-methylene-, (1R,4R,4aS,8aR)- ARTEMISININIC ACID 4,11(13)-AMorphadien-12-oic acid 4,11(13)-Cadinadien-12-oic acid 2-[(1R,4R,4aS,8aR)-4,7-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalen-1-yl]prop-2-enoic acid Artemisia Acid 1-Naphthaleneacetic acid, 1,2,3,4,4a,5,6,8a-octahydro-4,7-dimethyl-α-methylene-, (1R,4R,4aS,8aR)- (+)-artemisinicaci Dihydroartemisinic Artemisic Acid 2-((1R,4R,4aS,8aR)-4,7-Dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalen-1-yl)acrylic acid (+)-Artemisinic Acid Arteannuic acid,inhibit,Qing Hao acid,Inhibitor,Artemisic acid,Bacterial Artemisic acid, 10 mM in DMSO 80286-58-4 chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract Miscellaneous Natural Products