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ChemicalBook >> CAS DataBase List >>1,3,5-Tri-O-benzoyl-D-ribofuranose

1,3,5-Tri-O-benzoyl-D-ribofuranose

1,3,5-Tri-O-benzoyl-D-ribofuranose Structure
1,3,5-Tri-O-benzoyl-D-ribofuranose structure
CAS No.
22224-41-5
Chemical Name:
1,3,5-Tri-O-benzoyl-D-ribofuranose
Synonyms
Clofarabine Impurity 5;1,3,5-Bz-D-ribofuranose;1,3,5-tri-benzoyl-α-D-ribose;1,3,5-tri-O-Benzoyl-alpha-D-Ri;Clofarabine intermediate (III);1,3,5-TRIBENZOYL-A-D-RIBOFURANOSE;1,3,5-Tribenzoyl-α-D-ribofuranose;1,3,5-Tri-O-benzoyl-D-ribofuranose;1,3,5-Tribenzoate-α-D-Ribofuranose;1,3,5-tribenzoate-a-D-Ribofuranose
CBNumber:
CB7138063
Molecular Formula:
C26H22O8
Molecular Weight:
462.45
MDL Number:
MFCD00080818
MOL File:
22224-41-5.mol
Last updated:2025-08-21 22:16:43
Product description Number Pack Size Price
α-D-Ribofuranose 1,3,5-tribenzoate 97% 389080 5g $93.3
1,3,5-Tri-O-benzoyl-α-D-ribofuranose >97.0%(HPLC) T2641 5g $96
1,3,5-Tri-O-benzoyl-α-D-ribofuranose >97.0%(HPLC) T2641 25g $329
1,3,5-Tri-O-benzoyl-α-D-ribofuranose B209535 10g $70
1,3,5-Tri-O-benzoyl-a-D-ribofuranose 294691 1g $300
More product size
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1,3,5-Tri-O-benzoyl-D-ribofuranose Properties

Melting point 125-129 °C(lit.)
Boiling point 629.6±55.0 °C(Predicted)
Density 1.37±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Ethyl Acetate (Slightly)
form Powder
pka 12.35±0.70(Predicted)
color Pale brown
optical activity [α]20/D +85.0°, c = 1 in chloroform
Water Solubility Insoluble in water, easily soluble in chloroform.
λmax 273nm(MeOH)(lit.)
BRN 98446
InChIKey HUHVPBKTTFVAQF-QFBXJQHPSA-N
SMILES O(C(=O)C1=CC=CC=C1)C1O[C@H](COC(=O)C2=CC=CC=C2)[C@@H](OC(=O)C2=CC=CC=C2)[C@H]1O |&1:11,22,32,r|
CAS DataBase Reference 22224-41-5(CAS DataBase Reference)
UNSPSC Code 12352201
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS08
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319-H335-H351b
Precautionary statements  P261-P264b-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P330-P362+P364-P403+P233-P501c
Safety Statements  22-24/25
WGK Germany  3
HS Code  29400090
NFPA 704
1
0 0

1,3,5-Tri-O-benzoyl-D-ribofuranose price More Price(48)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 389080 α-D-Ribofuranose 1,3,5-tribenzoate 97% 22224-41-5 5g $93.3 2023-06-20 Buy
TCI Chemical T2641 1,3,5-Tri-O-benzoyl-α-D-ribofuranose >97.0%(HPLC) 22224-41-5 5g $96 2025-07-31 Buy
TCI Chemical T2641 1,3,5-Tri-O-benzoyl-α-D-ribofuranose >97.0%(HPLC) 22224-41-5 25g $329 2025-07-31 Buy
TRC B209535 1,3,5-Tri-O-benzoyl-α-D-ribofuranose 22224-41-5 10g $70 2021-12-16 Buy
Usbiological 294691 1,3,5-Tri-O-benzoyl-a-D-ribofuranose 22224-41-5 1g $300 2021-12-16 Buy
Product number Packaging Price Buy
389080 5g $93.3 Buy
T2641 5g $96 Buy
T2641 25g $329 Buy
B209535 10g $70 Buy
294691 1g $300 Buy

1,3,5-Tri-O-benzoyl-D-ribofuranose Chemical Properties,Uses,Production

Chemical Properties

White to off-white powder

Uses

It is employed as a starting material for nucleosides and is an intermediate fir cloforabine.

Uses

Starting material for nucleosides.

Synthesis

beta-D-Ribofuranose 1-acetate 2,3,5-tribenzoate

6974-32-9

1,3,5-Tri-O-benzoyl-D-ribofuranose

22224-41-5

Synthesis of compound vi: Compound v (2.57 mmol) was dissolved in 26 mL of anhydrous dichloromethane, and the reaction lasted for 2.5 h under the condition of ice-water bath with slow passage of dry HCl gas. After completion of the reaction, the reaction solution was washed with 19.5 mL of ice water and the organic layer was separated. The organic layer was washed sequentially with saturated sodium bicarbonate solution until the aqueous layer was weakly basic, and then washed with ice water until the aqueous layer was neutral. The organic layer was dried with anhydrous sodium sulfate for more than 4 hours and subsequently concentrated under reduced pressure to give a light yellow syrupy product. The syrup was recrystallized using a solvent mixture of hexane and dichloromethane to give the white solid compound vi in 65.1% yield.1H NMR (CDCl3) δ ppm: 7.36-8.14 (m, 15H, OBz), 6.68 (d, J = 4.4 Hz, 1H, H-1), 5.59 (dd, 1H, H-3), 4.64-4.80 ( m, 4H, H-2, H-4 and H-5). Melting point: 139-140°C.

References

[1] Patent: EP2177527, 2010, A1. Location in patent: Page/Page column 11
[2] Journal of Organic Chemistry, 1985, vol. 50, # 14, p. 2597 - 2598

1,3,5-Tri-O-benzoyl-D-ribofuranose Preparation Products And Raw materials

Raw materials

beta-D-Ribofuranose 1-acetate 2,3,5-tribenzoate Dichloromethane Hydrochloric acid

Preparation Products

3',5'-DI-O-BENZOYL-5-FLUORO-2'-O-METHYLURIDINE

1,3,5-Tri-O-benzoyl-D-ribofuranose Suppliers

Global( 311)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		+86-（0）57185586718; +8613336195806 sales@capot.com China 29734 60
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21620 55
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29852 58
Jinan Carbotang Biotech Co.,Ltd. 		+8615866703830 figo.gao@foxmail.com China 8497 58
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28172 58
Xiamen AmoyChem Co., Ltd 		+86-86-5926051114 +8615060885618 sales@amoychem.com China 6369 58
Nanjing Baifuli Technology Co., Ltd. 		+86-15335185688 sales@unisyn.cn CHINA 332 58
Standardpharm Co. Ltd. 		86-714-3992388 overseasales1@yongstandards.com United States 14332 58
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19552 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49975 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
Henan Tianfu Chemical Co.,Ltd. 		55
career henan chemical co 		58
Jinan Carbotang Biotech Co.,Ltd. 		58
Hubei Jusheng Technology Co.,Ltd. 		58
Xiamen AmoyChem Co., Ltd 		58
Nanjing Baifuli Technology Co., Ltd. 		58
Standardpharm Co. Ltd. 		58
BOC Sciences 		58
CONIER CHEM AND PHARMA LIMITED 		58

View Lastest Price from 1,3,5-Tri-O-benzoyl-D-ribofuranose manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1,3,5-Tri-O-benzoyl-D-ribofuranose pictures 2025-10-20 1,3,5-Tri-O-benzoyl-D-ribofuranose
22224-41-5
 US $0.00-0.00 / g 100g 97%min 10000g WUHAN FORTUNA CHEMICAL CO., LTD
1,3,5-Tri-O-benzoyl-D-ribofuranose pictures 2025-08-21 1,3,5-Tri-O-benzoyl-D-ribofuranose
22224-41-5
 US $0.00-0.00 / mg 10g TargetMol Chemicals Inc.
1,3,5-Tri-O-benzoyl-D-ribofuranose pictures 2025-04-04 1,3,5-Tri-O-benzoyl-D-ribofuranose
22224-41-5
 US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.

1,3,5-Tri-O-benzoyl-D-ribofuranose Spectrum

1,3,5-Tri-O-benzoyl-D-ribofuranose(22224-41-5)1HNMR1,3,5-Tri-O-benzoyl-D-ribofuranose(22224-41-5)IR1,3,5-Tri-O-benzoyl-D-ribofuranose(22224-41-5)FT-IR1,3,5-Tri-O-benzoyl-D-ribofuranose(22224-41-5)Raman

22224-41-5(1,3,5-Tri-O-benzoyl-D-ribofuranose)Related Search:

Denatonium Benzoate Dibenzofuran Emamectin benzoate Benzoyl peroxide Sodium benzoate
Benzoyl chloride Benzyl benzoate Benzofuran Sofosbuvir alpha-D-erythro-Pentofuranous-2-ulose 1,3,5-tribenzoate
Sofosbuvir Impurity26 SofosBuvir Impurity 2 1-((2S,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione sofosBuvir Impurity 33 sofosBuvir impurity 49
SofosBuvir Impurity 55 Sofosbuvir Impurity 84 PSI 7411

1of4

1,3,5-TRI-O-BENZOYL-ALPHA-D-RIBOFURANOSE 1,3,5-TRI-O-BENZOYL-ALPHA-D-RIBOFURANOSIDE 1,3,5-Tri-O-benzoyl-D-ribofuranose 1,3,5-TRIBENZOATE-ALPHA-D-RIBOFURANOSE [5-(benzoyloxy)-2-(benzoyloxymethyl)-4-hydroxyoxolan-3-yl] benzoate ALPHA-D-RIBOFURANOSE 1,3,5-TRIBENZOATE α-D-Ribofuranose, 1,3,5-tribenzoate a-D-Ribofuranose, 1,3,5-tribenzoate 1,3,5-Tri-O-Benzoyl-A-D-Ribofuranose 1,3,5-TRIBENZOYL-A-D-RIBOFURANOSE 1,3,5-Tri-O-Benzoyl-alpha-D-Ribofuranose(a-D-Ribofluranose-1,3,5-Tribenzoate) 1,3,5-tri-O-Benzoyl-alpha-D-Ri 1,3,5-tri-benzoyl-α-D-ribose Clofarabine intermediate (III) 1,3,5-TRI-O-BENZOYL-ALPHA-D-RIBOFURANOSE 98% 1,3,5-Tribenzoate-α-D-Ribofuranose 1,3,5-Tribenzoyl-α-D-ribofuranose 1,3,5-Tri-O-benzoyl-α-D-ribofuranose ,98% 1,3,5-tribenzoate-a-D-Ribofuranose 1,3,5-Tribenzoyl-alpha-D-ribofuranose 1,3,5-Tri-O-Benzoyl-alpha-D-Ribofuranose Min98% C2 PR-002 1,3,5-Tri-O-benzoyl-D-ribofuranose 1,3,5-Tri-O-benzoyl-D-ribofuranose (Decitabine) 1,3,5-Tri- O -benzoyl-α-D-ribofuranoside 1,3,5-Tri-O-benzoyl-alpha-D-ribofuranose, 97% pale brown powder 1,3,5- three -O- benzoyl -a-D- furan ribos [(2R,3S,4R,5R)-3,5-dibenzoyloxy-4-hydroxy-tetrahydrofuran-2-yl]methyl benzoate [3,5-BIS(BENZOYLOXY)-4-HYDROXYOXOLAN-2-YL]METHYL BENZOATE 1,3,5-Bz-D-ribofuranose Clofarabine Impurity 5 1,3,5-tribenzoyl - α - d-ribofuran 1，3，5-Tri-O-benzoyl-α-D-ribofuranose 1,3,5-Tri-O-benzoyl-D-ribofuranose USP/EP/BP (2R,3S,4R)-3,5-bis(benzoyloxy)-4-hydroxyoxolan-2-yl]methyl benzoate [(2R,5R)-3,5-dibenzoyloxy-4-hydroxyoxolan-2-yl]methyl benzoate α-D-Ribofuranose 1,3,5-tribenzoate α-D-Ribofuranose, 1,3,5-tribenzoate (6CI, 9CI, ACI) 1,3,5-tribenzoyl- α- D-furan ribose 1,3,5-Tri-O-benzoyesl-α-D-ribofuranose α-D-Ribofuranose 1,3,5-tribenzoate 22224-41-5 222224-41-5 C26H22O8 Carbohydrate Synthesis Specialty Synthesis Monosaccharides API intermediates (intermediate of clofarabine) Sugars, Carbohydrates & Glucosides 22224-41-5