N-ISOPROPYL-2-CHLOROACETAMIDE
- CAS No.
- 2895-21-8
- Chemical Name:
- N-ISOPROPYL-2-CHLOROACETAMIDE
- Synonyms
- 2-CHLORO-N-ISOPROPYLACETAMIDE;AKOS USSH-4110464;BUTTPARK 80\07-100;OTAVA-BB BB7020410060;N-ISOPROPYL CHLOROACETAMIDE;N-ISOPROPYL-2-CHLOROACETAMIDE;N-(Chloroacetyl)isopropylamine;N1-ISOPROPYL-2-CHLOROACETAMIDE;N-Isopropylchloroacetamide,97%;2-chloro-N-propan-2-yl-ethanamide
- CBNumber:
- CB7141214
- Molecular Formula:
- C5H10ClNO
- Molecular Weight:
- 135.59
- MDL Number:
- MFCD00068034
- MOL File:
- 2895-21-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2-Chloro-N-isopropylacetamide | 417119 | 250mg | $382 |
| 2-Chloro-N-isopropylacetamide | 417119 | 1g | $531 |
| 2-Chloro-N-isopropylacetamide 97% | OR25475 | 1g | $32 |
| 2-Chloro-N-isopropylacetamide 97% | OR25475 | 5g | $89 |
| 2-Chloro-N-isopropylacetamide 97% | OR25475 | 25g | $255 |
| More product size | |||
| Melting point | 58-60°C |
|---|---|
| Boiling point | 250.6±23.0 °C(Predicted) |
| Density | 1.052±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | Acetone, Chloroform, Dichloromethane, DMSO, Ethyl Acetate, Methanol |
| form | Solid |
| pka | 14.08±0.46(Predicted) |
| color | Dark Brown |
| BRN | 1745034 |
| InChI | InChI=1S/C5H10ClNO/c1-4(2)7-5(8)3-6/h4H,3H2,1-2H3,(H,7,8) |
| InChIKey | GYPNJSBBOATUPK-UHFFFAOYSA-N |
| SMILES | C(NC(C)C)(=O)CCl |
| CAS DataBase Reference | 2895-21-8(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36/37/39 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2924190090 | |||||||||
| NFPA 704 |
|
N-ISOPROPYL-2-CHLOROACETAMIDE price More Price(41)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 417119 | 2-Chloro-N-isopropylacetamide | 2895-21-8 | 250mg | $382 | 2026-06-03 | Buy |
| Usbiological | 417119 | 2-Chloro-N-isopropylacetamide | 2895-21-8 | 1g | $531 | 2026-06-03 | Buy |
| Apolloscientific | OR25475 | 2-Chloro-N-isopropylacetamide 97% | 2895-21-8 | 1g | $32 | 2026-06-04 | Buy |
| Apolloscientific | OR25475 | 2-Chloro-N-isopropylacetamide 97% | 2895-21-8 | 5g | $89 | 2026-06-04 | Buy |
| Apolloscientific | OR25475 | 2-Chloro-N-isopropylacetamide 97% | 2895-21-8 | 25g | $255 | 2026-06-04 | Buy |
N-ISOPROPYL-2-CHLOROACETAMIDE Chemical Properties,Uses,Production
Uses
2-Chloro-N-isopropylacetamide is an intermediate in synthesizing Prothoate (P838810), which can be used as analyte in analytical study of a new method of detecting multi-residue of organophosphorus pesticide.
Synthesis
75-31-0
79-04-9
2895-21-8
The general procedure for the synthesis of N-isopropylchloroacetamide from isopropylamine and chloroacetyl chloride was as follows: isopropylamine (236.4 mg, 4.0 mmol) was dissolved in 4 mL of dichloromethane, followed by the addition of anhydrous potassium carbonate (663.4 mg, 4.8 mmol). The reaction flask was cooled in an ice bath and chloroacetyl chloride (451.8 mg, 4.0 mmol) was slowly added dropwise through a dropping funnel. After the dropwise addition, the reaction mixture was stirred at room temperature overnight. Upon completion of the reaction, 10 mL of ice water was added to quench the reaction. The aqueous phase was extracted with dichloromethane and the organic phases were combined, washed with saturated brine and dried over anhydrous magnesium sulfate. The solvent was removed by distillation under reduced pressure to give a white solid product without further purification. The yield was 70.3%.
References
[1] Journal of Organic Chemistry, 2012, vol. 77, # 9, p. 4261 - 4270
[2] Journal of the American Chemical Society, 2009, vol. 131, p. 1106 - 1114
[3] ChemistryOpen, 2014, vol. 3, # 6, p. 238 - 241
[4] ACS Medicinal Chemistry Letters, 2017, vol. 8, # 6, p. 678 - 681
[5] Patent: CN106146414, 2016, A. Location in patent: Paragraph 0472; 0473; 0474
N-ISOPROPYL-2-CHLOROACETAMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32997 | 60 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8491 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 | laboratory@coreychem.com | China | 30203 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34526 | 58 |
| Henan Alfa Chemical Co., Ltd | +8618339805032 | sale03@alfachem.cn | China | 9817 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19904 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +86-15355479329 | market18@leapchem.com | China | 43303 | 58 |
| XIAMEN AMITY INDUSTRY AND TRADE CO., LTD. | +8618950047208 | ellena@amitychem.com | China | 43392 | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53799 | 58 |
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