3-(Trifluoromethyl)-2-pyridinecarbonitrile
- CAS No.
- 406933-21-9
- Chemical Name:
- 3-(Trifluoromethyl)-2-pyridinecarbonitrile
- Synonyms
- 3-Trifluoromethylpicolinonitrile;2-Cyano-3-trifluoromethylpyridine;3-trifluoromethyl-2-pyridinitrile;3-(trifluoroMethyl)-2-pyridinecarbonitrile;2-Pyridinecarbonitrile, 3-(trifluoromethyl)-;3-(Trifluoromethyl)-2-picolinonitrile, 2-Cyano-3-(trifluoromethyl)pyridine;3-Trifluoromethyl-2-pyridinecarbonitrile 2-Cyano-3-trifluoromethylpyridine
- CBNumber:
- CB71471129
- Molecular Formula:
- C7H3F3N2
- Molecular Weight:
- 172.11
- MDL Number:
- MFCD02091399
- MOL File:
- 406933-21-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 2-Cyano-3-trifluoromethylpyridine | FC54380 | 250mg | $150 |
| 2-Cyano-3-trifluoromethylpyridine | FC54380 | 100mg | $150 |
| 2-Cyano-3-trifluoromethylpyridine | FC54380 | 50mg | $150 |
| 2-Cyano-3-trifluoromethylpyridine | FC54380 | 500mg | $190 |
| 3-(Trifluoromethyl)pyridine-2-carbonitrile >98% | PC200149 | 5g | $21 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2933399990 |
3-(Trifluoromethyl)-2-pyridinecarbonitrile price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FC54380 | 2-Cyano-3-trifluoromethylpyridine | 406933-21-9 | 250mg | $150 | 2026-06-04 | Buy |
| Biosynth | FC54380 | 2-Cyano-3-trifluoromethylpyridine | 406933-21-9 | 100mg | $150 | 2026-06-04 | Buy |
| Biosynth | FC54380 | 2-Cyano-3-trifluoromethylpyridine | 406933-21-9 | 50mg | $150 | 2026-06-04 | Buy |
| Biosynth | FC54380 | 2-Cyano-3-trifluoromethylpyridine | 406933-21-9 | 500mg | $190 | 2026-06-04 | Buy |
| Apolloscientific | PC200149 | 3-(Trifluoromethyl)pyridine-2-carbonitrile >98% | 406933-21-9 | 5g | $21 | 2026-06-04 | Buy |
3-(Trifluoromethyl)-2-pyridinecarbonitrile Chemical Properties,Uses,Production
Synthesis
65753-47-1
406933-21-9
The general procedure for the synthesis of 3-trifluoromethyl-2-pyridinecarbonitrile from 2-chloro-3-trifluoromethylpyridine was as follows: 2-chloro-3-trifluoromethylpyridine (5 g, 28.9 mmol) was dissolved in dimethylformamide (40 ml) under the protection of nitrogen, and zinc cyanide (2 g, 17.4 mmol), zinc powder (85 mg, 1.3 mmol) and 1,1'- diphenylphosphine ferrocene palladium(II) dichloride complex with dichloromethane (460 mg, 0.63 mmol). The reaction mixture was heated to reflux and kept for 4 hours. After completion of the reaction, it was cooled to room temperature, diluted with ethyl acetate and washed with saturated saline. The aqueous phase was back-extracted with ethyl acetate, the organic phases were combined, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure. Purification by fast column chromatography (eluent: hexane solution of 20% ethyl acetate) afforded 3-trifluoromethyl-2-pyridinecarbonitrile (4.67 g, 98% yield) as a yellow oil.1H NMR (400 MHz, CDCl3) δ 8.59 (1H, dd, J=4.4,1.2 Hz), 8.05-8.02 (1H, m), 7.40- 7.37 (1H, m) ppm.
References
[1] Patent: WO2004/74290, 2004, A1. Location in patent: Page 45
[2] Patent: US2004/53929, 2004, A1
3-(Trifluoromethyl)-2-pyridinecarbonitrile Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| HaBo Hong Kong Co., Limited. | +86-25-18512596065 | info@habotech.com | CHINA | 933 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
| Changzhou Carman Chemical Co., Ltd. | 15061933924 | CHINA | 514 | 58 | |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Shanghai Rlavie Technology Co ltd | +86-021-67759270 +8617717059219 | sales@rlavie.com | China | 1030 | 58 |
| Blocksynth Pharmaceutical Technology Co.,Ltd | 0086-19817745290; +8619817745290 | bd@blocksynth.com | China | 5973 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
| CD Chemical Group Limited | +8615986615575 | info@codchem.com | China | 17259 | 58 |
View Lastest Price from 3-(Trifluoromethyl)-2-pyridinecarbonitrile manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2022-01-04 | 3-Trifluoromethyl-pyridine-2-carbonitrile
406933-21-9
|
1g | 98%min | 100kgs/month | Shanghai Rlavie Technology Co ltd | ||
 |
2020-01-05 | 2-Cyano-3-trifluoromethylpyridine
406933-21-9
|
$9.80 | 1g | ≥99% | 100kg | Career Henan Chemical Co |
-
- 3-Trifluoromethyl-pyridine-2-carbonitrile
406933-21-9
- 98%min
- Shanghai Rlavie Technology Co ltd
-
- 2-Cyano-3-trifluoromethylpyridine
406933-21-9
- $9.80
- ≥99%
- Career Henan Chemical Co
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