ChemicalBook >> CAS DataBase List >>4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-1H-INDAZOLE

4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-1H-INDAZOLE

4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-1H-INDAZOLE structure

CAS No.: 885618-33-7

Chemical Name:: 4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-1H-INDAZOLE

Synonyms: 2-dioxaborolan-2-;1H-indazol-4-boronic;Indazole-4-boronic acid p...;2-dioxaborolan-2-yl)-1H-indazole;Pinacol ester indazole-4-boronic acid;1H-Indazole-4-boronic acid picol ester;1H-indazol-4-boronic acid pinacol ester;1H-Indazole-4-boronic acid pinacol ester;1H-Indazol-4-ylboronic Acid Pinacol Ester;1H-Indazole-4-boronic acid pinacol ester, 95%,

CBNumber:: CB71501910

Molecular Formula:: C13H17BN2O2

Molecular Weight:: 244.1

MDL Number:: MFCD08059267

MOL File:: 885618-33-7.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 02:42:13

Product description	Number	Pack Size	Price
4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-indazole Asreported	291297	100mg	$363
4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-indazole Asreported	291297	250mg	$463
4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-indazole Asreported	291297	500mg	$623
4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-indazole Asreported	291297	1g	$914
4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-indazole Asreported	291297	2g	$1257
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4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-1H-INDAZOLE Properties

Melting point	139-142℃
storage temp.	Inert atmosphere,2-8°C
form	solid
color	White to off-white
InChI	InChI=1S/C13H17BN2O2/c1-12(2)13(3,4)18-14(17-12)10-6-5-7-11-9(10)8-15-16-11/h5-8H,1-4H3,(H,15,16)
InChIKey	YRPXZCWDXBNPBD-UHFFFAOYSA-N
SMILES	N1C2=C(C(B3OC(C)(C)C(C)(C)O3)=CC=C2)C=N1

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H332-H335

Precautionary statements

P261-P280-P305+P351+P338

HS Code

2933998090

NFPA 704

	0
0		0

4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-1H-INDAZOLE price More Price(74)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Usbiological	291297	4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-indazole Asreported	885618-33-7	100mg	$363	2026-06-03	Buy
Usbiological	291297	4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-indazole Asreported	885618-33-7	250mg	$463	2026-06-03	Buy
Usbiological	291297	4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-indazole Asreported	885618-33-7	500mg	$623	2026-06-03	Buy
Usbiological	291297	4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-indazole Asreported	885618-33-7	1g	$914	2026-06-03	Buy
Usbiological	291297	4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-indazole Asreported	885618-33-7	2g	$1257	2026-06-03	Buy

Product number	Packaging	Price	Buy
291297	100mg	$363	Buy
291297	250mg	$463	Buy
291297	500mg	$623	Buy
291297	1g	$914	Buy
291297	2g	$1257	Buy

4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-1H-INDAZOLE Chemical Properties,Uses,Production

Synthesis

73183-34-3

186407-74-9

4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-1H-INDAZOLE

885618-33-7

To a solution of 4-bromo-1H-indazole (500 mg, 2.54 mmol) and bis(pinacolato)diboron (1.5 eq, 3.81 mmol) in dimethyl sulfoxide (DMSO, 20 mL) was added dry potassium acetate (3.0 eq, 7.61 mmol, 747 mg) and PdCl2(dppf)2 (3 mol%, 0.076 mmol, 62 mg). The reaction mixture was degassed with argon and the reaction was heated at 80 °C for 40 hours. After completion of the reaction, it was cooled to room temperature and the reaction mixture was partitioned between water (50 mL) and ether (3 x 50 mL). The organic layers were combined, washed with brine (50 mL), separated and dried over anhydrous magnesium sulfate (MgSO4). The crude product was purified by column chromatography using 30%-40% ethyl acetate/petroleum ether as eluent to give a non-separable 3:1 mixture of 1H-indazole-4-boronic acid pinacol ester (369 mg, 60%) and unreacted 4-bromo-1H-indazole (60 mg, 20%). The mixture was a yellow gel that solidified to an off-white solid upon standing.1H NMR (400 MHz, DMSO-d6) data were as follows:1H-indazole-4-boronic acid pinacol ester (70): δ 1.41 (12H, s), 7.40 (1H, dd, J = 8.4 Hz, 6.9 Hz), 7.59 (1H, d, J = 8.4 Hz), 7.67 (1H, d, J = 6.9 Hz), 10.00 (1H, br s), 8.45 (1H, s); 4-bromo-1H-indazole: δ 7.40 (1H, m), 7.18 (1H, t, J = 7.9 Hz), 7.50 (1H, d, J = 9.1 Hz), 7.77 (1H, d, J = 7.9 Hz), 8.09 (1H, s). The impurity peak appeared at δ 1.25.

References

[1] Patent: WO2007/42806, 2007, A1. Location in patent: Page/Page column 34-35
[2] Patent: WO2011/130628, 2011, A1. Location in patent: Page/Page column 128
[3] Patent: US2013/102595, 2013, A1. Location in patent: Paragraph 0173
[4] Patent: JP2015/187145, 2015, A. Location in patent: Paragraph 0171
[5] Bioorganic and Medicinal Chemistry, 2014, vol. 22, # 3, p. 1156 - 1162

4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-1H-INDAZOLE synthesis

Synthesis of 4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-1H-INDAZOLE from Bis(pinacolato)diboron and 4-Bromo-1H-indazole

4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-1H-INDAZOLE Preparation Products And Raw materials

Raw materials

4-Nitro-1H-indazole 3-Bromo-2-methylaniline 1-Acetyl-4-bromo-1H-indazole 1H-INDAZOL-4-AMINE 4-Bromo-1H-indazole

2-Methyl-3-nitroaniline Dimethyl sulfoxide Potassium Acetate Bis(pinacolato)diboron

1of2

Preparation Products

Indazole

4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-1H-INDAZOLE Suppliers

Global( 143)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	+86-13017695106 +86-13676922317	jiuyitime@fdachem.com	China	16512	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29815	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58
Fuxin Pharmaceutical	+86-021-021-50872116 +8613122107989	contact@fuxinpharm.com	China	10000	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
PharmOrgSyn Laboratories Co., Ltd.	+86-021-38228826 +86-13916602830	sales@pharmorgsyn.cn	China	139	58

Supplier	Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	58
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Accela ChemBio Inc.	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Fuxin Pharmaceutical	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
PharmOrgSyn Laboratories Co., Ltd.	58

View Lastest Price from 4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-1H-INDAZOLE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-04-17	4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole 885618-33-7	$22.00-88.00	1kg	99%	50kg	ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
	2019-07-10	4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-1H-INDAZOLE 885618-33-7	$1.00	1KG	98%	150KG	Career Henan Chemical Co

4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole
885618-33-7
$22.00-88.00
99%
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-1H-INDAZOLE
885618-33-7
$1.00
98%
Career Henan Chemical Co

4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-1H-INDAZOLE Spectrum

4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-1H-INDAZOLE(885618-33-7)¹HNMR

885618-33-7(4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-1H-INDAZOLE)Related Search:

1-Methyl-1H-indazole-4-boronic acid pinacol ester Indazole-4-boronic acid, hydrochloride 6-FLUORO-4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-1H-INDAZOLE 4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-1H-INDAZOLE

1H-Indazole, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)- 1H-Indazol-4-ylboronic Acid Pinacol Ester 1H-Indazole-4-boronic acid pinacol ester Indazole-4-boronic acid p... 2-dioxaborolan-2-yl)-1H-indazole 4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1h-indazole 3-hydroxy-2,3-dimethylbutan-2-yl hydrogen 1H-indazol-4-ylboronate 1H-indazol-4-boronic acid pinacol ester Pinacol ester indazole-4-boronic acid 2-dioxaborolan-2- 1H-Indazole-4-boronic acid picol ester 1H-Indazole-4-boronic acid pinacol ester, 95%, 1H-indazol-4-boronic Indazole-4-boronic acid pinacol ester - [I0255] 885618-33-7 Indazoles